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Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2\; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009].. Zusätzlich bieten wir Ihnen Cyclin Y Kits (17) und Cyclin Y Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal Cyclin Y Primary Antibody für IHC, IHC (p) - ABIN4288911
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
CycY/Eip63E form a cyclin (zeige PCNA Antikörper)/Cdk (zeige CDK4 Antikörper) complex that is essential for several developmental processes.
findings revealed an unrecognized role of Caprin-2 (zeige CAPRIN2 Antikörper) in facilitating LRP5 (zeige LRP5 Antikörper)/6 constitutive phosphorylation at G2/M through forming a quaternary complex with CDK14 (zeige CDK14 Antikörper), Cyclin Y, and LRP5 (zeige LRP5 Antikörper)/6.
we believe that CCNY has biological effect in breast cancer (BC) development, and its inhibition via an RNA interference lentiviral system may provide a therapeutic option for BC
CCNY was significantly upregulated in ovarian cancer cell lines and tissues. Significant association was observed between CCNY expression and clinicopathological stage and lymph node metastasis. It significantly exacerbated proliferation, migration, and invasion of A2780 cells, in vitro and in nude mice. It significantly increased c-Myc (zeige MYC Antikörper), cyclin D1 (zeige CCND1 Antikörper), PFTK1 (zeige CDK14 Antikörper), ki67 (zeige MKI67 Antikörper), and OGT (zeige OGT Antikörper) protein expressions in xenograft tumor tissues.
Activation of PCTAIRE-1 (zeige CDK16 Antikörper) is mediated through interaction with the phosphorylated form of cyclin Y in complex with 14-3-3 (zeige YWHAQ Antikörper).
Our findings highlight a PFTK1 (zeige CDK14 Antikörper)-CCNY complex in activating noncanonical Wnt (zeige WNT2 Antikörper) signaling in HCC (zeige FAM126A Antikörper) cells.
Human cyclin Y (CCNY) is a phosphoprotein in vivo and phosphorylation of CCNY by CDK14 (zeige CDK14 Antikörper) triggers its ubiquitination and degradation.
Cyclin Y regulates the expression and membrane trafficing of PCTAIRE (zeige CDK16 Antikörper) kinases (PCTK). (Review)
CCNY (zeige CDK16 Antikörper)binding to CDK16 required a region upstream of the kinase domain and was found to be inhibited by phosphorylation of serine 153, a potential PKA phosphorylation site.
these results validated the role of CCNY as a clinically relevant human oncoprotein
CCNY might play an important role in glioma tumorigenisis.
Here we show that Cyclin Y-like 1 (Ccnyl1) and Cyclin Y (Ccny) have overlapping function and are crucial for mouse embryonic development and mammary stem/progenitor cell functions. Double knockout of Ccnys results in embryonic lethality at E16.5
these results provide a new link between CCNY and lipid metabolism in mice.
CDK16 (zeige CDK16 Antikörper) isolated from testis was unphosphorylated, interacted with CCNY, and exhibited kinase activity.
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2\; MIM 116940) (Li et al., 2009
, drosophila cyclin Y
, cyclin box protein 1
, cyclin fold protein 1
, cyclin-box carrying protein 1