anti-Crystallin, gamma C (CRYGC) Antikörper

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte CRYGC CRYGC 24277 P02529
Anti-Human CRYGC CRYGC 1420 P07315
Anti-Maus CRYGC CRYGC 12966 Q61597
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Top anti-CRYGC Antikörper auf antikoerper-online.de

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CRYGC Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>OVCAR-3 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample(30 ug whole cell lysate) A:A431, 12% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
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Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
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Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Human Kaninchen Unkonjugiert WB Western Blot: gamma C Crystallin Antibody [NBP1-52908] - Titration: 0.2-1 ug/ml, Positive Control: OVCAR-3 cell lysate. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
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Human Kaninchen Unkonjugiert WB Crystallin Gamma C antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
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Human Maus Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

Am meisten referenzierte anti-CRYGC Antikörper

  1. Human Polyclonal CRYGC Primary Antibody für IF (p), IHC (p) - ABIN1714542 : Aoki, Ogino, Tomita, Hara, Kunisada: Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells. in PLoS ONE 2016 (PubMed)

Weitere Antikörper gegen CRYGC Interaktionspartner

Human Crystallin, gamma C (CRYGC) Interaktionspartner

  1. the G129C mutation in gammaC-crystallin, which is associated with autosomal dominant congenital nuclear cataract, perturbed the unfolding process by promoting the accumulation of two distinct aggregation-prone intermediates under mild denaturing conditions.

  2. Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8 (zeige GJA8 Antikörper), CRYGC, PAX6 (zeige PAX6 Antikörper) and CYP1B1 (zeige CYP1B1 Antikörper).

  3. We confirm that congenital cataract is associated with a CRYGC gene mutation.

  4. identified a CRYAA (zeige CRYAA Antikörper) mutation in family A and a CRYGC mutation in family B with congenital cataract

  5. A nonsense mutation c.471G>A in CRYGC is associated with autosomal dominant congenital nuclear cataracts and microcornea in a Chinese pedigree.

  6. Molecular modeling and spectroscopic studies indicated that the mutation impaired the tertiary structure of gamma C crystallin by modifying the H-bonding network in the C-terminal domain.

  7. Two novel nonsynonymous variations and four reported variations in CRYAB (zeige CRYAB Antikörper), CRYGC, CRYGD (zeige CRYGD Antikörper), and GJA8 (zeige GJA8 Antikörper), were observed.

  8. In gammaD-crystallin, methylation is exclusively at Cys (zeige DNAJC5 Antikörper) 110, whereas in gammaC- and gammaB-crystallins, the principal methylation site is Cys (zeige DNAJC5 Antikörper) 22 with minor methylation at Cys (zeige DNAJC5 Antikörper) 79

  9. the loss of interactions of T5P mutant of the gammaC-crystallin with other crystallins may play a larger role than the protection afforded by chaperone-like activity in Coppock-like cataract.

  10. This is the first case of phenotypic heterogeneity in the primary congenital cataract specifically associated with the R168W mutation in the CRYGC gene.

Mouse (Murine) Crystallin, gamma C (CRYGC) Interaktionspartner

  1. a 1-bp deletion in gammaC-crystallin leads to cataract.

  2. presence of measurable interactions between MIP26 (zeige MIP Antikörper) and all crystallins, with the extent of interactions decreasing from alphaA- and alphaB-crystallin (zeige CRYAB Antikörper) to betaB2- and gammaC-crystallin.

Cow (Bovine) Crystallin, gamma C (CRYGC) Interaktionspartner

CRYGC Antigen-Profil

Protein Überblick

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Genbezeichner und Symbole assoziert mit CRYGC

  • crystallin, gamma C (Crygc) Antikörper
  • crystallin gamma C (CRYGC) Antikörper
  • crystallin gamma C L homeolog (crygc.L) Antikörper
  • crystallin, gamma C (CRYGC) Antikörper
  • crystallin gamma C (Crygc) Antikörper
  • gamma-crystallin C (LOC100069179) Antikörper
  • ccl Antikörper
  • Cryg Antikörper
  • Cryg-5 Antikörper
  • cryg3 Antikörper
  • CRYGC Antikörper
  • CTRCT2 Antikörper
  • Len Antikörper
  • MGC84008 Antikörper

Bezeichner auf Proteinebene für CRYGC

crystallin, gamma polypeptide 3 , gamma-C-crystallin , gamma-crystallin 2-1 , gamma-crystallin C , crystallin, gamma-3 , gamma-crystallin 3 , gammaC-crystallin , gamma-crystallin IIIA , crystallin, gamma C

GENE ID SPEZIES
24277 Rattus norvegicus
1420 Homo sapiens
12966 Mus musculus
281722 Bos taurus
444574 Xenopus laevis
709553 Macaca mulatta
737363 Pan troglodytes
100126770 Canis lupus familiaris
100337641 Cavia porcellus
100354942 Oryctolagus cuniculus
100069179 Equus caballus
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