anti-Crystallin, gamma C (CRYGC) Antikörper

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. Zusätzlich bieten wir Ihnen CRYGC Proteine (10) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CRYGC 24277 P02529
CRYGC 1420 P07315
CRYGC 12966 Q61597
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Top anti-CRYGC Antikörper auf

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CRYGC Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: OVCAR-3 cell lysate 100 μL 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB WB Image Sample(30 ug whole cell lysate) A:A431, 12% SDS PAGE antibody diluted at 1:1000 100 μL 3 bis 4 Tage
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
Human Maus Unkonjugiert WB 100 μL 11 bis 14 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of MCF7 and U251MG cells, using CRYGC antibody. 100 μL 11 bis 13 Tage
Human Kaninchen Unkonjugiert ELISA, WB 100 μL 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB Crystallin Gamma C antibody used at 1 ug/ml to detect target protein. 50 μg 9 bis 11 Tage
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL 11 bis 12 Tage
Human Kaninchen HRP IHC (p), WB   100 μL 14 bis 21 Tage
Human Kaninchen Cy7 IF (p)   100 μL 14 bis 21 Tage

Am meisten referenzierte anti-CRYGC Antikörper

  1. Human Polyclonal CRYGC Primary Antibody für IF (p), IHC (p) - ABIN1714542 : Aoki, Ogino, Tomita, Hara, Kunisada: Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells. in PLoS ONE 2016 (PubMed)

Weitere Antikörper gegen CRYGC Interaktionspartner

Human Crystallin, gamma C (CRYGC) Interaktionspartner

  1. Identification of a novel CRYGC exon 2 mutation in a pedigree affected with congenital cataracts

  2. Study identified eight different mutations in CRYGC associated with autosomal dominant congenital nuclear cataracts (ADCC) in a cohort of Chinese family and shows that CRYGC mutations are responsible for 4.1% of ADCC families in the cohort. The results expand the spectrum of CRYGC mutations as well as their associated phenotypes.

  3. We examined a cohort of Chinese patients with congenital cataracts and studied the phenotypes and genotypes. Extralenticular abnormalities, such as microcornea and ocular coloboma, can also be found in patients with congenital cataracts. The phenotype of congenital cataracts associated with macular and optic disc coloboma was reported for the first time in this study.

  4. the G129C mutation in gammaC-crystallin, which is associated with autosomal dominant congenital nuclear cataract, perturbed the unfolding process by promoting the accumulation of two distinct aggregation-prone intermediates under mild denaturing conditions.

  5. Exome sequencing in developmental eye disease leads to identification of causal variants in GJA8, CRYGC, PAX6 and CYP1B1.

  6. We confirm that congenital cataract is associated with a CRYGC gene mutation.

  7. identified a CRYAA mutation in family A and a CRYGC mutation in family B with congenital cataract

  8. A nonsense mutation c.471G>A in CRYGC is associated with autosomal dominant congenital nuclear cataracts and microcornea in a Chinese pedigree.

  9. Molecular modeling and spectroscopic studies indicated that the mutation impaired the tertiary structure of gamma C crystallin by modifying the H-bonding network in the C-terminal domain.

  10. Transgenic expression of mutant CRYGC5bpd gamma-crystallin at near-physiological levels causes lens opacities and fiber cell defects, confirming the pathogenicity of this mutation.

  11. Two novel nonsynonymous variations and four reported variations in CRYAB, CRYGC, CRYGD, and GJA8, were observed.

  12. The T5P mutation obviously changes conformation and decreases conformational stability.

  13. calculation of the standard free-energy by equilibrium unfolding transition in guanidine hydrochloride

  14. In gammaD-crystallin, methylation is exclusively at Cys 110, whereas in gammaC- and gammaB-crystallins, the principal methylation site is Cys 22 with minor methylation at Cys 79

  15. the loss of interactions of T5P mutant of the gammaC-crystallin with other crystallins may play a larger role than the protection afforded by chaperone-like activity in Coppock-like cataract.

  16. This is the first case of phenotypic heterogeneity in the primary congenital cataract specifically associated with the R168W mutation in the CRYGC gene.

  17. Identification of a novel nonsense mutation in CRYGC in a Chinese family with autosomal dominant congenital nuclear cataracts and microcornea.

  18. Report a new nonsense mutation (Y56X) in CRYGD and a prev'ly reported missense mutation (R12C) in CRYAA associated with nuclear autosomal dominant congenital cataract in Brazilian families. A new polymorphism (S119S) in CRYGC was observed in one family.

Mouse (Murine) Crystallin, gamma C (CRYGC) Interaktionspartner

  1. a 1-bp deletion in gammaC-crystallin leads to cataract.

  2. presence of measurable interactions between MIP26 and all crystallins, with the extent of interactions decreasing from alphaA- and alphaB-crystallin to betaB2- and gammaC-crystallin.

Cow (Bovine) Crystallin, gamma C (CRYGC) Interaktionspartner

  1. The results are consistent with the hypothesis that short-range, weak, attractive interactions between alpha- and gamma-crystallins are necessary for maximum transparency of the lens.

CRYGC Antigen-Profil

Protein Überblick

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Genbezeichner und Symbole assoziert mit CRYGC

  • crystallin, gamma C (Crygc) Antikörper
  • crystallin gamma C (CRYGC) Antikörper
  • crystallin gamma C L homeolog (crygc.L) Antikörper
  • crystallin, gamma C (CRYGC) Antikörper
  • crystallin gamma C (Crygc) Antikörper
  • gamma-crystallin C (LOC100069179) Antikörper
  • ccl Antikörper
  • Cryg Antikörper
  • Cryg-5 Antikörper
  • cryg3 Antikörper
  • CRYGC Antikörper
  • CTRCT2 Antikörper
  • Len Antikörper
  • MGC84008 Antikörper

Bezeichner auf Proteinebene für CRYGC

crystallin, gamma polypeptide 3 , gamma-C-crystallin , gamma-crystallin 2-1 , gamma-crystallin C , crystallin, gamma-3 , gamma-crystallin 3 , gammaC-crystallin , gamma-crystallin IIIA , crystallin, gamma C

24277 Rattus norvegicus
1420 Homo sapiens
12966 Mus musculus
281722 Bos taurus
444574 Xenopus laevis
709553 Macaca mulatta
737363 Pan troglodytes
100126770 Canis lupus familiaris
100337641 Cavia porcellus
100354942 Oryctolagus cuniculus
100069179 Equus caballus
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