Collagen, Type I, alpha 2 Proteine (COL1A2)

COL1A2 encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Zusätzlich bieten wir Ihnen Collagen, Type I, alpha 2 Antikörper (119) und Collagen, Type I, alpha 2 Kits (78) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
COL1A2 1278 P08123
COL1A2 12843 Q01149
Ratte COL1A2 COL1A2 84352 P02466
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Top Collagen, Type I, alpha 2 Proteine auf antikoerper-online.de

Showing 9 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Hund Unkonjugiert SDS-PAGE analysis of Dog COL1A2 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$668.03
Details
Hefe Kaninchen His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,678.50
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$656.00
Details
Escherichia coli (E. coli) Huhn Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$653.82
Details
Escherichia coli (E. coli) Rind (Kuh) Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$653.82
Details
Escherichia coli (E. coli) Kaninchen Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$653.82
Details

COL1A2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu Collagen, Type I, alpha 2 (COL1A2) Interaktionspartnern

Human Collagen, Type I, alpha 2 (COL1A2) Interaktionspartner

  1. Structural basis of homo- and heterotrimerization of COL1A1 (zeige COL1A1 Proteine)/ COL1A2 has been reported.

  2. Osteogenesis imperfecta with ectopic mineralizations in dentin and cementum and a COL1A2 mutation has been reported in a Thai adult patient and his preschool daughter.

  3. Mutations in the COL1A1 (zeige COL1A1 Proteine) and COL1A2 genes associated with osteogenesis imperfecta (OI) types I or III.

  4. High COL1A2 expression is associated with Gastric Cancer.

  5. The aim of this study is to determine whether EcoRI, Del38 and PvuII polymorphisms of COL1A2 are associated with the development of osteoporosis and osteopenia in post-menopausal Polish women. The analyzed COL1A2 polymorphisms seem to be related to osteoporosis development. The COL1A2 polymorphism may be a genetic risk factor related to the development of osteoporosis.

  6. the efficacy of pamidronate treatment does not seem to be related to the genotype of type I collagen in patients with osteogenesis imperfecta.

  7. COL1A2 gene mutation is associated with osteogenesis imperfecta.

  8. We evaluated the association of a 7-base pair (7-bp) indel polymorphism (rs3917) in the 3'UTR of COL1A2 with the risk of sudden cardiac death in a Chinese population. Our data provided initial evidence that rs3917 was highly relevant to SCD (zeige SCD Proteine) susceptibility, and this indel may become a potential marker for molecular diagnosis and genetic counseling of SCD (zeige SCD Proteine).

  9. meta-analysis suggests COL1A2 rs42524 is a significant risk factor for Intracranial Aneurysm susceptibility.

  10. mutations of the COL1A1 (zeige COL1A1 Proteine) and COL1A2 genes probably underlie the disease in the four families

Cow (Bovine) Collagen, Type I, alpha 2 (COL1A2) Interaktionspartner

  1. In advanced stage granulomas in Mycobacterium bovis-infected cattle, there was an increase in the expression of type I procollagen

  2. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

Mouse (Murine) Collagen, Type I, alpha 2 (COL1A2) Interaktionspartner

  1. miR (zeige MLXIP Proteine)-26b-5p interacted with 3'UTRs of Col1a2 and CTGF (zeige CTGF Proteine), and circ_000203 could block the interactions of miR (zeige MLXIP Proteine)-26b-5p and 3'UTRs of Col1a2 and CTGF (zeige CTGF Proteine).

  2. mouse with a Gly610 to cysteine (Cys (zeige DNAJC5 Proteine)) substitution in the procollagen alpha2(I) chain show misfolded procollagen accumulation in the endoplasmic reticulum leads to an unusual form of cell stress.

  3. these results indicate that mutant collagen alpha2(I) chain affects both bone quantity and composition.

  4. Activation of COL1A2 transcription by HIF-1alpha (zeige HIF1A Proteine) occurred in the absence of hypoxia and is strongly enhanced by TGF-beta (zeige TGFB1 Proteine) signaling.

  5. Identify PDGFRbeta as a driver in activating Akt (zeige AKT1 Proteine)/mTORC1 nexus for high glucose-mediated expression of collagen I (alpha2) in proximal tubular epithelial cells, which contributes to tubulointerstitial fibrosis in diabetic nephropathy.

  6. Insulin receptor substrate-1 (zeige IRS1 Proteine) time-dependently regulates bone formation by controlling collagen Ialpha2 expression via miR (zeige MLXIP Proteine)-342

  7. Type I collagen was highly expressed in the spinal cord during the scar-forming phase and induced astrocytic scar formation via the integrin-N-cadherin (zeige CDH2 Proteine) pathway.

  8. evidence that FOXL2 (zeige FOXL2 Proteine) modulates Col1a2 transcription through interaction with a response element 65 Kb upstream of the transcription start site

  9. Data indicate that insulin-like growth factor 1 (IGF1 (zeige IGF1 Proteine)) could promote collagen I alpha 2 (COL1A2) expression and osteoblast differentiation in primary pre-osteoblasts by increasing La ribonucleoprotein domain family member 6 (Larp6 (zeige LARP6 Proteine)) expression via a posttranscriptional mechanism.

  10. The phosphorylation sequence matched that targeted by Casein Kinase 2, and inhibition of this kinase activity disrupted the ability of scleraxis to modulate the expression of its target genes while also attenuating TGFbeta (zeige TGFB1 Proteine)-induced expression of type I collagen and myofibroblast phenotype conversion marker genes

Pig (Porcine) Collagen, Type I, alpha 2 (COL1A2) Interaktionspartner

Zebrafish Collagen, Type I, alpha 2 (COL1A2) Interaktionspartner

  1. ven though in adult bone, skin and scales equal amounts of a1(col1a1a) a2(col1a2) and a3(col1a2)chains are present, the presented data suggest a tissue-specific stoichiometry and/or post-translational modification status for collagen type I

Collagen, Type I, alpha 2 (COL1A2) Protein Überblick

Protein Überblick

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Genbezeichner und Symbole assoziert mit COL1A2

  • collagen type I alpha 2 chain (COL1A2)
  • collagen type I alpha 2 L homeolog (col1a2.L)
  • collagen, type I, alpha 2 (Col1a2)
  • collagen type I alpha 2 chain (Col1a2)
  • collagen, type I, alpha 2 (col1a2)
  • AA960264 Protein
  • AI325291 Protein
  • alpha2(I) Protein
  • Col1a-2 Protein
  • Cola-2 Protein
  • Cola2 Protein
  • hm:zehn2357 Protein
  • OI4 Protein
  • oim Protein
  • wu:fa98d05 Protein
  • wu:fa99g10 Protein
  • wu:fb04c08 Protein
  • wu:fb11d06 Protein
  • zehn2357 Protein

Bezeichner auf Proteinebene für COL1A2

procollagen, type I, alpha 2 , alpha 2(I) collagen , alpha-2 type I collagen , alpha-2(1) collagen , collagen alpha 2(I) chain , collagen alpha-2(I) chain , alpha 2(I)-collagen , collagen I, alpha-2 polypeptide , collagen of skin, tendon and bone, alpha-2 chain , type I procollagen , COL1A2 gene exons 8 through 12 , type I procollagen pro-alpha 2 chain , alpha 2(I) procollagen , collagen I alpha-2 polypeptide , collagen COL1A2 , osteogenesis imperfecta , alpha 2 type I collagen , collagen a2(I)

GENE ID SPEZIES
100860940 Capra hircus
380419 Xenopus laevis
396243 Gallus gallus
1278 Homo sapiens
403824 Canis lupus familiaris
282188 Bos taurus
100008997 Oryctolagus cuniculus
12843 Mus musculus
84352 Rattus norvegicus
100719158 Cavia porcellus
100626716 Sus scrofa
336471 Danio rerio
100135811 Oncorhynchus mykiss
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