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Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and. Zusätzlich bieten wir Ihnen Cleavage and Polyadenylation Specific Factor 2, 100kDa Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal CPSF2 Primary Antibody für ICC, IF - ABIN256695
Tran, Saran, Williamson, Pierce, Dittrich-Breiholz, Wiehlmann, Koch, Whetton, Tamura: THOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100). in Nucleic acids research 2014
Show all 2 Pubmed References
Human Polyclonal CPSF2 Primary Antibody für ICC, IF - ABIN4300324
Kolev, Yario, Benson, Steitz: Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation. in EMBO reports 2008
Cow (Bovine) Polyclonal CPSF2 Primary Antibody für WB - ABIN2779108
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
Cpsf2,Ppil2 (zeige PPIL2 Antikörper), and SNAP-25 (zeige SNAP25 Antikörper) are the most promising targets for the NSm protein of the virus during an infection.
CPSF2 may have a role in Papillary Thyroid Carcinoma
CPSF2 and SYMPK (zeige SYMPK Antikörper), are RBFOX2 (zeige RBM9 Antikörper) cofactors for both inclusion and exclusion of internal exons.
Decreased CPSF2 expression is associated with increased cellular invasion and cancer stem cell population, and more aggressive disease in papillary thyroid cancer.
Conserved residues in CPSF2 and CPSF-73 (zeige CPSF3 Antikörper) are required for assembly of the endonuclease activity that cleaves histone pre-mRNAs.
The data suggest a key role for CPSF100 in locating poly(A) sites and affecting transcription termination.
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing (By similarity).
cleavage and polyadenylation specific factor 2, 100kDa
, cleavage and polyadenylation specificity factor subunit 2
, cleavage and polyadenylation specific factor 2
, CPSF 100 kDa subunit
, cleavage and polyadenylation specific factor 2, 100kD subunit
, cleavage and polyadenylation specificity factor 100 kDa subunit
, CPSF 100kDa subunit