Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Proteine (CSTF2T)

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Zusätzlich bieten wir Ihnen Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant Antikörper (37) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CSTF2T 83410 Q8C7E9
CSTF2T 23283 Q9H0L4
Ratte CSTF2T CSTF2T 309338  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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CSTF2T Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Interaktionspartnern

Mouse (Murine) Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Interaktionspartner

  1. Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice

  2. This demonstrates that tauCstF-64 is an important stage-specific regulator of Crem (zeige CREM Proteine) mRNA processing that modulates the spatial and temporal expression of downstream stage-specific genes necessary for the proper development of sperm in mice.

  3. The results suggest that tauCstF-64 plays a role in 3' end determination and transcription termination for a large range of germ cell-expressed genes.

  4. tauCstF-64 is required not only for expression of genes involved in morphological differentiation of spermatids but also for genes having products that function during interaction of motile spermatozoa with eggs.

  5. physiologically increased levels of CstF-64 (zeige CSTF2 Proteine) observed in LPS (zeige TLR4 Proteine)-stimulated RAW macrophages contribute to the changes in expression and alternative polyadenylation of a number of genes

  6. These results suggest the hypothesis that tauCstF-64 mRNA is regulated at the translational or post-translational level.

  7. tauCstF-64 promotes germ-cell-specific patterns of polyadenylation by binding to different downstream sequence elements.

  8. Targeted disruption of Cstf2t in mice causes aberrant spermatogenesis, specifically disrupting meiotic and postmeiotic development, resulting in male infertility resembling oligoasthenoteratozoospermia.

  9. The Cstf2t protein contributes to proteomic diversity by regulating alternative polyadenylation of neural mRNAs.

Human Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Interaktionspartner

  1. Studied expression levels of CstF-64 (zeige CSTF2 Proteine) in EV71-infected cells; showed reduction of CstF-64 (zeige CSTF2 Proteine) during virus infection correlated with production of viral 3C(pro). CstF-64 (zeige CSTF2 Proteine) was cleaved in vitro by 3C(pro) not by mutant 3C(pro) variants.

  2. Radiation hybrid mapping places the human tauCstF-64 gene at 10q22-q23, which is the site of a translocation that has been associated with human neurological problems and male infertility.

  3. structure of the RNA-binding domain of CstF-64 (zeige CSTF2 Proteine) containing an RNA recognition motif (RRM) augmented by N- and C-terminal helices

  4. upstream element in human papillomavirus type 16 interacted specifically with CstF-64 (zeige CSTF2 Proteine), hnRNP C1/C2 (zeige HNRNPC Proteine) & polypyrimidine tract binding protein (zeige PTBP1 Proteine), suggesting these factors were enhancing or regulating polyadenylation at the HPV-16 early polyadenylation signal

Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T) Protein Überblick

Protein Überblick

May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs.

Genbezeichner und Symbole assoziert mit CSTF2T

  • cleavage stimulation factor, 3' pre-RNA subunit 2, tau (Cstf2t)
  • cleavage stimulation factor subunit 2 tau variant (CSTF2T)
  • cleavage stimulation factor subunit 2, tau variant (Cstf2t)
  • 64kDa Protein
  • C77975 Protein
  • CstF-64T Protein
  • tauCstF-64 Protein
  • tCstF-64 Protein

Bezeichner auf Proteinebene für CSTF2T

CF-1 64 kDa subunit tau , CF-1 64 kDa subunit, tau , CSTF 64 kDa subunit tau , CSTF 64 kDa subunit, tau , cleavage stimulation factor 64 kDa subunit tau , cleavage stimulation factor 64 kDa subunit, tau , cleavage stimulation factor subunit 2 tau , cleavage stimulation factor subunit 2 tau variant , cleavage stimulation factor, 3' pre-RNA subunit 2, 64 kDa, tau , tauCstF-64 , cleavage stimulation factor, 3' pre-RNA subunit 2, tau

GENE ID SPEZIES
83410 Mus musculus
23283 Homo sapiens
783569 Bos taurus
309338 Rattus norvegicus
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