Chromosome 4 Open Reading Frame 49 Proteine (C4orf49)

Plays a role in the trafficking of mitochondria along microtubules.

alle Proteine anzeigen Gen GeneID UniProt
Maus C4orf49 C4orf49 67749 Q8VI64
Human C4orf49 C4orf49 84709 Q8TDB4
Ratte C4orf49 C4orf49 689931  
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Top Chromosome 4 Open Reading Frame 49 Proteine auf antikoerper-online.de

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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,649.05
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Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
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Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$6,616.87
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Wheat germ Human GST tag   10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$328.90
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Weitere Proteine zu Chromosome 4 Open Reading Frame 49 (C4orf49) Interaktionspartnern

Mouse (Murine) Chromosome 4 Open Reading Frame 49 (C4orf49) Interaktionspartner

  1. The ratio of motile mitochondria was remarkably decreased in the axons of MGARP-overexpressing cells.

  2. These results indicate that HUMMR does not play a key role in mitochondrial dysfunction in the APP (zeige APP Proteine)/PS1 (zeige PSEN1 Proteine) double transgenic Alzheimer disease mouse

  3. MGARP participates in hormone biosynthesis while being under the regulation of the hormones derived from the hypothalamic-pituitary-gonadal axis.

  4. Results identify a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) as one of the highly expressed proteins in retina [MGARP].

  5. HUMMR (Hypoxia Upregulated Mitochondrial Movement Regulator) is induced by HIF-1 and regulates mitochondrial distribution and movement in neurons during hypoxia

  6. OSAP is prominently expressed in steroidogenic tissues; results suggest that OSAP is involved in steroidogenesis, potentially through its ability to maintain mitochondrial abundance and morphology

Human Chromosome 4 Open Reading Frame 49 (C4orf49) Interaktionspartner

  1. The present study identified a proximal core sequence in the MGARP promoter that is composed of two enriched Sp1 (zeige PSG1 Proteine) binding motifs and established Sp1 (zeige PSG1 Proteine) as one major MGARP transactivator.

  2. Results identify a mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) as one of the highly expressed proteins in retina [MGARP].

  3. Results identify a novel mitochondria protein, hypoxia up-regulated mitochondrial movement regulator (HUMMR), which is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 alpha (HIF-1alpha (zeige HIF1A Proteine)).

  4. OSAP is prominently expressed in steroidogenic tissues; results suggest that OSAP is involved in steroidogenesis, potentially through its ability to maintain mitochondrial abundance and morphology

Chromosome 4 Open Reading Frame 49 (C4orf49) Protein Überblick

Protein Überblick

Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity).

Genbezeichner und Symbole assoziert mit C4orf49

  • mitochondria localized glutamic acid rich protein (Mgarp)
  • mitochondria localized glutamic acid rich protein (MGARP)
  • mitochondria-localized glutamic acid-rich protein (Mgarp)
  • 4930583H14Rik Protein
  • AI195347 Protein
  • C4orf49 Protein
  • CESP-1 Protein
  • HUMMR Protein
  • OSAP Protein
  • Qsap Protein

Bezeichner auf Proteinebene für C4orf49

corneal endothelium-specific protein 1 , hypoxia up-regulated mitochondrial movement regulator protein , mitochondria-localized glutamic acid-rich protein , ovary-specific acidic protein , protein MGARP , hypoxia up-regulated mitochondrial movement regulator

GENE ID SPEZIES
67749 Mus musculus
84709 Homo sapiens
689931 Rattus norvegicus
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