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CHD3 encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. Zusätzlich bieten wir Ihnen CHD3 Antikörper (80) und CHD3 Kits (20) und viele weitere Produktgruppen zu diesem Protein an.
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This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
, chromodomain helicase DNA binding protein 3
, similar to CHD3
, chromodomain-helicase-DNA-binding protein 3-like
, ATP-dependent helicase CHD3
, chromodomain-helicase-DNA-binding protein 3
, mi-2 autoantigen 240 kDa protein
, zinc finger helicase
, zinc-finger helicase (Snf2-like)
, Mi-2 alpha
, CHD3-like protein