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Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Zusätzlich bieten wir Ihnen CBX6 Proteine (3) und CBX6 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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Findings indicate that chromobox 6 (CBX6) is an essential component of embryonic stem cells (ESCs) biology that contributes to the structural and functional complexity of the polycomb repressive complex 1 (PRC1) complex.
different CBX proteins are recruited to distinct chromatin regions through nonconserved interactions. Metaphase spreads revealed reciprocal patterns of chromosome association by CBX2 and CBX6
Data show that USP26 interacts with PRC1 components chromobox (CBX)-containing proteins CBX4 and CBX6.
our results represent the first evidence that CBX6 contributes to tumor progression and indicate that the protein may serve as a novel prognostic biomarker for hepatocellular carcinoma and as a therapeutic target in the treatment of the disease.
Data show that polycomb-group proteins BMI1, PHC3, CBX6 and CBX7 expression was significantly increased during imatinib treatment.
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
chromobox homolog 6
, chromobox protein homolog 6
, chromobox-like protein 6
, chromobox 6