anti-Chromobox Homolog 5 (CBX5) Antikörper

Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human CBX5 CBX5 23468 P45973
Anti-Ratte CBX5 CBX5 300266  
Anti-Maus CBX5 CBX5 12419 Q61686
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Top anti-CBX5 Antikörper auf antikoerper-online.de

Showing 10 out of 301 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185491 (0.03µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185491 (2.5µg/ml) staining of paraffin embedded Human Uterus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert ChIP, IHC (p), IP, IHC, PLA, WB Immunohistochemistry-Paraffin: HP1 alpha Antibody [ABIN2582353] - Human prostate carcinoma. Antibody used at a dilution of 1:5,000 (0.2ug/ml). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-CBX5 Antibody Titration:  1.25ug/ml  Positive Control:  Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IC, IF, IP, IHC, WB Immunofluorescent analysis of HP1 alpha staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of HP1 alpha staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB CBX5 Antibody (Center) (ABIN657701) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the CBX5 antibody detected the CBX5 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert ChIP, ICC, IF   100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$495.83
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HP1 alpha (Phospho-Ser92) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with insulin 0.01U/ml 15', using HP1 alpha (Ab-92) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using HP1 alpha (Ab-92) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HeLa/A549/K562 cells, using CBX5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to CBX5 on HeLa cell (antibody concentration 10 µg/mL).  CBX5 monoclonal antibody (M01), clone 1E11-3A10 Western Blot analysis of CBX5 expression in HeLa NE. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details

Am meisten referenzierte anti-CBX5 Antikörper

  1. Human Polyclonal CBX5 Primary Antibody für ChIP, IHC (p) - ABIN258235 : Bawa-Khalfe, Lu, Zuo, Huang, Dere, Lin, Yeh: Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CBX5 Primary Antibody für ChIP, ICC - ABIN2668529 : Shestakova, Mansuroglu, Mokrani, Ghinea, Bonnefoy: Transcription factor YY1 associates with pericentromeric gamma-satellite DNA in cycling but not in quiescent (G0) cells. in Nucleic acids research 2004 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal CBX5 Primary Antibody für IF, WB - ABIN2452033 : Wang, Koyama, Nishida, Haraguchi, Reith, Tsukamoto: The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells. in Molecular and cellular biology 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CBX5 Primary Antibody für IHC (p), IHC - ABIN250893 : Rohr, Lecestre, Chasserot-Golaz, Marban, Avram, Aunis, Leid, Schaeffer: Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cells. in Journal of virology 2003 (PubMed)

Weitere Antikörper gegen CBX5 Interaktionspartner

Human Chromobox Homolog 5 (CBX5) Interaktionspartner

  1. KDM2A (zeige KDM2A Antikörper)-SF forms distinct nuclear heterochromatic bodies in an HP1a (zeige TFF1 Antikörper) dependent manner

  2. Data suggest that SUMOylated heterochromatin protein 1-alpha (HP1alpha)alpha is a critical epigenetic-regulator of DNA-repair in breast cancer (BCa (zeige BLNK Antikörper)) that could define chemotherapy responsiveness.

  3. findings suggest that heterochromatin-mediated gene silencing may occur in part through sequestration of compacted chromatin in phase-separated HP1 (zeige DEFA1 Antikörper) droplets, which are dissolved or formed by specific ligands on the basis of nuclear context

  4. Data show that SALL4 (zeige SALL4 Antikörper) promotes the expression of Glut1 (zeige SLC2A1 Antikörper) and open chromatin through a HP1alpha-dependent mechanism.

  5. Identify a nucleosome interaction module within KDM2A (zeige KDM2A Antikörper) consisting of a CXXC type zinc finger, a PHD (zeige PDC Antikörper) domain and a newly identified Heterochromatin Protein 1 (HP1 (zeige DEFA1 Antikörper)) interaction motif that mediates direct binding between KDM2A (zeige KDM2A Antikörper) and HP1 (zeige DEFA1 Antikörper). This nucleosome interaction module enables KDM2A (zeige KDM2A Antikörper) to decode nucleosomal H3K9me3 modification in addition to CpG methylation signals.

  6. These data suggests that up-regulated HP1A (zeige TFF1 Antikörper) and H3K9me3 in glioma cells are functionally associated with glioma pathogenesis and progression.

  7. Loss of HP1alpha and gamma isoforms inhibits the upregulation of Suv39h1 (zeige SUV39H1 Antikörper) and H3K9me3 that is observed under stress conditions.

  8. we showed the essential role of HP1 (zeige DEFA1 Antikörper) in regulating HR through BRCA1/BARD1 (zeige BARD1 Antikörper)-mediated accumulation of FANCJ (zeige BRIP1 Antikörper) and CtIP (zeige RBBP8 Antikörper) at DSB sites. This mechanism may affect tumorigenesis and chemosensitivity and is thus of high clinical significance.

  9. We demonstrate that an hnRNPA1 (zeige HNRNPA1 Antikörper) and CBX5 bi-directional core promoter fragment does not comprise intrinsic capacity for specific CBX5 down-regulation in metastatic cells

  10. HP1alpha plays an important role in the differentiation and angiogenic function of Endothelial Progenitor Cells.

Mouse (Murine) Chromobox Homolog 5 (CBX5) Interaktionspartner

  1. HP1-alpha oligomerization is critical to the maintenance of heterochromatin and the tunable dynamics of this HP1 isoform.

  2. demonstrate an actin-driven differential modulation of core histone H2B and heterochromatin HP1alpha protein dynamics with chromatin

  3. the molecular behavior of HP1alpha throughout the cell cycle

  4. There is a functional link between prelamin A, HP1alpha, chromatin remodeling, DNA repair, and early senescence in Zmpste24 (zeige Zmpste24 Antikörper)-deficient mice, suggesting a potential therapeutic strategy for laminopathy-based premature aging via the intervention of HP1alpha.

  5. the TIF1beta (zeige TRIM28 Antikörper)-HP1 system functions as a critical repressive machinery that targets genes not normally activated in the hematopoietic compartment, thereby maintaining the transcriptional signature specific to HSCs.

  6. HP1 mobility in apoptotic cells appeared to be unique.

  7. Elimination of HP1alpha by siRNA interfered with centromere relocation from heterochromatin surrounding NPBs to pro-chromocenters at the two-cell stage but did not affect preimplantation develoment to the blastocyst stage.

  8. Depletion of Senp7 (zeige SENP7 Antikörper) delocalizes HP1 alpha from pericentric heterochromatin without affecting H3K9me3 levels.

  9. The interplay between MU2 (zeige AP2M1 Antikörper) and HP1a is dynamic and may be different in euchromatin and heterochromatin during DNA break recognition and repair.

  10. KAP1 (zeige TRIM28 Antikörper) and HP1 tether activation-induced cytidine deaminase (zeige AICDA Antikörper) (AID) to H3K9me3 residues at the donor switch region, thus linking AID to epigenetic modifications during class switch recombination.

CBX5 Antigen-Profil

Protein Überblick

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit CBX5

  • chromobox 5 (CBX5) Antikörper
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila) (cbx5) Antikörper
  • chromobox 5 (Cbx5) Antikörper
  • chromobox 5 S homeolog (cbx5.S) Antikörper
  • chromobox 5 (cbx5) Antikörper
  • 2610029O15Rik Antikörper
  • C75991 Antikörper
  • cbx5 Antikörper
  • HP1 Antikörper
  • Hp1a Antikörper
  • Hp1alpha Antikörper
  • id:ibd2026 Antikörper
  • MGC64354 Antikörper
  • wu:fc63e02 Antikörper
  • wu:fe47g12 Antikörper
  • wu:fi03h05 Antikörper
  • zgc:158601 Antikörper

Bezeichner auf Proteinebene für CBX5

HP1 alpha homolog , HP1-ALPHA , HP1Hs alpha , antigen p25 , chromobox homolog 5 (HP1 alpha homolog, Drosophila) , chromobox protein homolog 5 , heterochromatin protein 1 homolog alpha , heterochromatin protein 1-alpha , fc63e02 , chromobox-like protein 5 , chromobox-like protein 5 (HP1 alpha homolog, Drosophila) , HP1 alpha , chromobox homolog 5 , heterochromatin protein 1 alpha , mHP1(alpha) , chromobox homolog 5 tv3

GENE ID SPEZIES
23468 Homo sapiens
563396 Danio rerio
538885 Bos taurus
477593 Canis lupus familiaris
467011 Pan troglodytes
300266 Rattus norvegicus
100307036 Ovis aries
380557 Xenopus laevis
394502 Xenopus (Silurana) tropicalis
12419 Mus musculus
100519426 Sus scrofa
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