anti-Cholinergic Receptor, Muscarinic 2 (CHRM2) Antikörper

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. Zusätzlich bieten wir Ihnen Muscarinic Acetylcholine Receptor M2 Kits (55) und Muscarinic Acetylcholine Receptor M2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CHRM2 1129 P08172
CHRM2 243764 Q9ERZ4
CHRM2 81645 P10980
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Top anti-Muscarinic Acetylcholine Receptor M2 Antikörper auf antikoerper-online.de

Showing 10 out of 177 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from HeLa/MCF-7 cells, using CHRM2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of LOVO cells, using CHRM2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB CHRM2 Antibody (Center)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CHRM2 antibody detected the CHRM2 protein (arrow). Western blot analysis of CHRM2 (arrow) using rabbit polyclonal CHRM2 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CHRM2 gene. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of rat brain membranes: 1. Anti-M2 Muscarinic Receptor antibody, (1:200). 2. Anti-M2 Muscarinic Receptor antibody, preincubated with the control fusion protein antigen. Expression of M2 Muscarinic Receptor in mouse parieto-temporal cortex sections Immunohistochemical staining of mouse parieto-temporal cortex frozen sections (non-consecutive) using Anti-Kir3.2 (GIRK2) antibody, (1:100) and Anti-M2 Muscarinic Receptor antibody, (1:100). M2 Muscarinic Receptor staining (red) was dense in layer IV, with fibers climbing to layers II-III. Kir3.2 K+ channel staining (green) was dense in layers IV and I. Overlapping expression of Kir3.2 channel and M2 muscarinic Receptor is seen in cortical layers. 50 μL Anmelden zum Anzeigen 10 bis 11 Tage
$678.57
Details
Fledermaus Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody [NLS1331] - Analysis of anti-CHRM2 / M2 antibody with human brain, neurons and glia. Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody [NLS1331] - Analysis of anti-CHRM2 / M2 antibody with human brain, glioblastoma. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Hund Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti ChRM2 Polyclonal Antibody, Unconjugated (ABIN668646) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti ChRM2 Polyclonal Antibody, Unconjugated (ABIN668646) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody [NLS1333] - IHC analysis of brain, neurons and glia using this antibody at 6 ug/ ml. Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M2/CHRM2 Antibody [NLS1333] - Analysis of anti-CHRM2 / M2 antibody with human brain, glioblastoma. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Maus Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Meerschweinchen Maus Unkonjugiert Func, EIA, IHC (fro), IF, WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Anti-CHRM2 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048441 dilution 10 ug/ml. Anti-CHRM2 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048441 dilution 10 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p) Anti-CHRM2 antibody  ABIN1048440 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

CHRM2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Muscarinic Acetylcholine Receptor M2 Antikörper

  1. Rat (Rattus) Polyclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für WB - ABIN965894 : Zhou, Fryer, Jacoby: Structure of the human M(2) muscarinic acetylcholine receptor gene and its promoter. in Gene 2001 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für IHC, IHC (fro) - ABIN4336776 : Levey, Edmunds, Hersch, Wiley, Heilman: Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat. in The Journal of comparative neurology 1995 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für Func, IA - ABIN2192224 : Elies, Fu, Eftekhari, Wallukat, Schulze, Granier, Hjalmarson, Hoebeke: Immunochemical and functional characterization of an agonist-like monoclonal antibody against the M2 acetylcholine receptor. in European journal of biochemistry / FEBS 1998 (PubMed)
    Show all 2 Pubmed References

  4. Bat Polyclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für IHC (p) - ABIN270607 : Yankiwski, Noonan, Neff: The C-terminal domain of the Bloom syndrome DNA helicase is essential for genomic stability. in BMC cell biology 2002 (PubMed)

  5. Dog (Canine) Polyclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für IF (p), IHC (p) - ABIN668646 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

  6. Cow (Bovine) Polyclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für IHC (p) - ABIN4336774 : Strang, Renna, Amthor, Keyser: Muscarinic acetylcholine receptor localization and activation effects on ganglion response properties. in Investigative ophthalmology & visual science 2010 (PubMed)

  7. Mouse (Murine) Polyclonal Muscarinic Acetylcholine Receptor M2 Primary Antibody für ELISA, WB - ABIN4336778 : Hendershot, Bryan, Ewing, Claus, Hutchison: Preliminary evidence for associations of CHRM2 with substance use and disinhibition in adolescence. in Journal of abnormal child psychology 2011 (PubMed)

Weitere Antikörper gegen Muscarinic Acetylcholine Receptor M2 Interaktionspartner

Human Cholinergic Receptor, Muscarinic 2 (CHRM2) Interaktionspartner

  1. Results show reduced autonomic nervous system (ANS) activity in association with the CHRM2 rs8191992 polymorphism in patients with schizophrenia on high-dose antipsychotics. CHRM2 polymorphisms may play an important role in ANS activity in patients with schizophrenia.

  2. Data suggest that levels of CHRM2 are lower in Brodmann's area 24 from subjects with mood disorders, and it is possible that signalling by that receptor is also less in this cortical region; increasing levels of CHRM2 may be involved in the mechanisms of action of mood stabilisers and tricyclic antidepressants

  3. Report a significant association between CHRM2 (rs1824024) polymorphism and disease severity, lower lung function test values, frequent exacerbations, and poor response to anti-cholinergic drugs in COPD (zeige ARCN1 Antikörper) patients.

  4. Inactivation of M2 AChR/NF-kappaB (zeige NFKB1 Antikörper) signaling axis reverses epithelial-mesenchymal transition and suppresses migration and invasion in non-small cell lung cancer.

  5. CHRM2 gene expression was dysregulated in the anterior cingulate of bipolar patients.

  6. This study demonstrated that CD4 (zeige CD4 Antikörper)+ and CD8 (zeige CD8A Antikörper)+ T cells expressed M2 and M4 muscarinic receptors which density were significantly increased in asthmatic children in comparison with controls.

  7. The expressed the fusion proteins of the muscarinic acetylcholine receptor M2 subtype with a maltose-binding protein and various G protein alpha (zeige GNAO1 Antikörper) subunits in Escherichia coli.

  8. CHRM2 but not CHRM1 (zeige CHRM1 Antikörper) or CHRM3 (zeige CHRM3 Antikörper) polymorphisms are associated with asthma susceptibility in Mexican patients.

  9. High Muscarinic Receptor M2 expression is associated with peripartum cardiomyopathy.

  10. [(3)H]LY2119620 to probe specifically the human M2 and M4 muscarinic receptor (zeige CHRM5 Antikörper) allosteric binding sites.

Mouse (Murine) Cholinergic Receptor, Muscarinic 2 (CHRM2) Interaktionspartner

  1. The three receptor sets considered (mAChR (zeige CHRM3 Antikörper), AR and TrkB (zeige NTRK2 Antikörper) receptors) intervene in modulating the conditions of the competition between nerve endings.

  2. In the present study, the functional coupling of Gi/o protein-coupled receptors to GalR1 (zeige GALR1 Antikörper), and the CB1 (zeige CNR1 Antikörper) receptor subtype for endocannabinoids were analyzed in the 3xTg-AD mice model of Alzheimer's disease in the prodromal and advanced stages. In addition, the activity mediated by Gi/o protein-coupled M2/4 (zeige GSDMD Antikörper) muscarinic receptor (zeige CHRM5 Antikörper) subtypes was also analyzed in brain areas involved in anxiety and cognition.

  3. Muscarinic M2 receptors in the circular muscular layer of mouse ileum exert a previously undocumented function in gut (zeige GUSB Antikörper) motility via the regulation of gap junctions

  4. IL-17 (zeige IL17A Antikörper) production in the hearts of M2AChR mice is dependent on P2x7 (zeige P2RX7 Antikörper) expression in dilated cardiomyopathy.

  5. Expression of the M2 receptors mediating cholinergic contractile stimuli of the detrusor muscle was dysregulated in both Mras (zeige MRAS Antikörper)-/- males and females, although only males exhibited a urinary phenotype.

  6. These results demonstrate that M2R are dysfunctional and do not affect ACh levels in PRiMA knockout mice, likely because of down-regulation and/or loss of receptor-effector coupling.

  7. Data indicate taht m2R-RGS6 (zeige RGS6 Antikörper)-IKACh pathway sets heart rate variability independently from the autonomic input.

  8. M2-mediated contractions in the M3KO and WT strains were decreased by the Rho kinase (zeige ROCK2 Antikörper) (ROCK) inhibitor Y27632 as well as the ROCK, PKA and PKG (zeige PRKG1 Antikörper) inhibitor H89.

  9. M2 receptor is co-localized with VGLUT2 on intraganglionic laminar endings of esophagus.

  10. Presence of M2 mAChR (zeige CHRM3 Antikörper) is sufficient and necessary to mediate the carbachol-induced membrane hyperpolarization and inhibition of SpECTs in laterodorsal tegmental nucleus neurons.

Zebrafish Cholinergic Receptor, Muscarinic 2 (CHRM2) Interaktionspartner

  1. cloning, characterization and expression patterns; results suggest that the M2 mAChR (zeige CHRM3 Antikörper) inhibits basal heart rate in zebrafish embryo and mediates carbachol-induced bradycardia

  2. The M(2) muscarinic receptor (zeige CHRM5 Antikörper) plays a specific role in the initiation of hypoxic bradycardia in fish.

Pig (Porcine) Cholinergic Receptor, Muscarinic 2 (CHRM2) Interaktionspartner

  1. Data suggest that both M(2) and M(3) muscarinic receptors mediate the contraction in both pig clasp (zeige CLASRP Antikörper) and sling fibers similar to human clasp (zeige CLASRP Antikörper) and sling fibers.

Cow (Bovine) Cholinergic Receptor, Muscarinic 2 (CHRM2) Interaktionspartner

  1. The original finding was the identification and purification of a vinpocetine and muscarinic antagonist-inhibited and CaM (zeige KRIT1 Antikörper)-activated plasma membrane-bound PDE1A (zeige PDE1A Antikörper), linked to M(2)AChR.

  2. airway M(2)Rs inhibit BK channels by a dual, Gbetagamma-mediated mechanism, a direct membrane-delimited interaction, and the activation of the phospholipase C (zeige PLC Antikörper)/protein kinase C (zeige PKC Antikörper) pathway

Rabbit Cholinergic Receptor, Muscarinic 2 (CHRM2) Interaktionspartner

  1. Data suggest that autoantibodies to beta-1 adrenergic receptor (ADRB1 (zeige ADRB1 Antikörper)) and muscarinic receptor M2 (CHRM2), along with elevated thyroxine (T4) levels, contribute to atrial tachyarrhythmia in Graves disease (GD); here, a rabbit model of GD is studied.

Muscarinic Acetylcholine Receptor M2 (CHRM2) Antigen-Profil

Protein Überblick

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

Genbezeichner und Symbole assoziert mit CHRM2

  • cholinergic receptor muscarinic 2 (CHRM2) Antikörper
  • cholinergic receptor, muscarinic 2, cardiac (Chrm2) Antikörper
  • cholinergic receptor, muscarinic 2a (chrm2a) Antikörper
  • muscarinic acetylcholine receptor M2-like (LOC100220676) Antikörper
  • cholinergic receptor, muscarinic 2 (Chrm2) Antikörper
  • cholinergic receptor muscarinic 2 (Chrm2) Antikörper
  • AChR-M2 Antikörper
  • Acm2 Antikörper
  • Chrm-2 Antikörper
  • chrm2 Antikörper
  • GPM2 Antikörper
  • HM2 Antikörper
  • M2 Antikörper

Bezeichner auf Proteinebene für CHRM2

7TM receptor , acetylcholine receptor, muscarinic 2 , muscarinic M2 receptor , muscarinic acetylcholine receptor M2 , AChR M2 , muscarinic acetylcholine receptor 2 , cholinergic receptor, muscarinic 2 , cardiac muscarinic acetylcholine receptor , muscarinic acetylcholine receptor m2 , m2 muscarinic acetylcholine receptor , Muscarinic acetylcholine receptor M2 , cholinergic receptor muscarinic 2 , muscarinic acetylcholine receptor M2-like , M2 muscarinic acetylcholine receptor , cholinergic receptor, muscarinic 2, cardiac , muscarinic receptor m2 , muscarinic receptor 2

GENE ID SPEZIES
1129 Homo sapiens
243764 Mus musculus
352938 Danio rerio
397498 Sus scrofa
403858 Canis lupus familiaris
418126 Gallus gallus
463758 Pan troglodytes
522170 Bos taurus
100220676 Taeniopygia guttata
100231098 Taeniopygia guttata
100342878 Oryctolagus cuniculus
100411083 Callithrix jacchus
100450243 Pongo abelii
100593190 Nomascus leucogenys
81645 Rattus norvegicus
100715343 Cavia porcellus
101102897 Ovis aries
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