Chloride Channel Accessory 2 (CLCA2) ELISA Kits

The protein encoded by CLCA2 belongs to the calcium sensitive chloride conductance protein family. Zusätzlich bieten wir Ihnen CLCA2 Antikörper (17) und CLCA2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human CLCA2 CLCA2 9635 Q9UQC9
Anti-Maus CLCA2 CLCA2 229933 Q8BG22
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Weitere ELISA Kits für CLCA2 Interaktionspartner

Human Chloride Channel Accessory 2 (CLCA2) Interaktionspartner

  1. CLCA2 links junctional adhesion molecule (zeige AMICA1 ELISA Kits) EVA1 (zeige MPZL2 ELISA Kits), to cytosolic signaling proteins that modulate proliferation and differentiation.

  2. CLCA2 expression is higher in squamous cell carcinoma of the lung compared with adenocarcinoma.

  3. Variants in CLCA2 were associated with an ileal involvement phenotype of Crohn's disease.

  4. These results strongly suggest that CLCA2 is involved in the p53 tumor suppressor (zeige TP53 ELISA Kits) network and has a significant effect on cell migration and invasion.

  5. hCLCA2 is required for epithelial differentiation, and its loss during tumor progression contributes to metastasis.

  6. the reduced expression of CLCA2 was frequently observed in various kinds of cancers including prostate cancer

  7. Expression of hSK4 as well as hCACC-2 and hCACC-3 but not hCACC-1 was demonstrated by reverse transcriptase PCR on native nasal tissues.

  8. immunohistochemistry clearly demonstrated colocalisation between hCLCA2 and integrin beta4

  9. human CLCA2 protein and mRNA expression are elevated during epithelial stratification, suggesting that this protein plays a role in the growth of multi-layered corneal epithelia during both natural development and tissue cultivation.

  10. hCLCA2 Is a p53 (zeige TP53 ELISA Kits)-Inducible Inhibitor of Breast Cancer Cell Proliferation.

Mouse (Murine) Chloride Channel Accessory 2 (CLCA2) Interaktionspartner

  1. Stat3 (zeige STAT3 ELISA Kits)-mediated regulation of expression of members of the calcium-activated chloride channel (zeige CLCA4 ELISA Kits) regulator (zeige CLNS1A ELISA Kits) (CLCA) family of proteins during involution and mammary carcinogenesis.

  2. basal NF-kappaB (zeige NFKB1 ELISA Kits) activity is involved in the Ca(2 (zeige CA2 ELISA Kits)+)-dependent regulation of mCLCA2 expression in a mouse keratinocyte line

  3. The results imply that mCLCA5 may play a role in maturation and keratinization of squamous epithelial cells.

  4. results establish mCLCA5 as the mouse ortholog of hCLCA2, demonstrate that mCLCA5 is a detachment-sensitive growth inhibitor, and suggest a mechanism whereby these channels may antagonize mammary tumor progression, metastases [CLCA5]

CLCA2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.

Genbezeichner und Symbole assoziert mit CLCA2

  • chloride channel accessory 2 (CLCA2) Antikörper
  • calcium-activated chloride channel regulator 2 (LOC100081268) Antikörper
  • chloride channel accessory 2 (Clca2) Antikörper
  • 4732440A06 Antikörper
  • AI586120 Antikörper
  • CACC Antikörper
  • CaCC-3 Antikörper
  • CACC3 Antikörper
  • Clca2 Antikörper
  • CLCRG2 Antikörper

Bezeichner auf Proteinebene für CLCA2

calcium-activated chloride channel regulator 2 , chloride channel accessory 2 , calcium-activated chloride channel regulator 2-like , CLCA family member 2, chloride channel regulator , calcium-activated chloride channel family member 2 , calcium-activated chloride channel protein 3 , calcium-activated chloride channel-2 , chloride channel regulator 2 , chloride channel, calcium activated, family member 2 , hCLCA2 , hCaCC-3 , calcium-activated chloride channel family member 5 , mCLCA5

GENE ID SPEZIES
534256 Bos taurus
711959 Macaca mulatta
100339003 Oryctolagus cuniculus
100385716 Callithrix jacchus
100471268 Ailuropoda melanoleuca
100511753 Sus scrofa
100081268 Ornithorhynchus anatinus
9635 Homo sapiens
229933 Mus musculus
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