anti-Chloride Channel 3 (CLCN3) Antikörper

CLCN3 encodes a member of the voltage-gated chloride channel (ClC) family. Zusätzlich bieten wir Ihnen Chloride Channel 3 Proteine (7) und Chloride Channel 3 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CLCN3 1182 P51790
CLCN3 84360 P51792
CLCN3 12725 P51791
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Showing 10 out of 105 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-CLCN3 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-CLCN3 Polyclonal Antibody, Unconjugated (ABIN1386131) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert WB CLCN3 Antibody (Center)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the CLCN3 antibody detected the CLCN3 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Ratte Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 5 bis 6 Tage
Human Kaninchen Unkonjugiert IHC, WB CLCN3 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Neural cells (arrows) in Human Brain. Magnification is at 400X CLCN3 antibody used at 1.25 ug/ml to detect target protein. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: CLCN3 Antibody [NBP1-91790] - Lane 1: Mouse liver tissue lysate Lane 2: Rat liver tissue lysate. Recommended dilution: 1:250 - 1:500 Immunohistochemistry-Paraffin: CLCN3 Antibody [NBP1-91790] - Staining of human hippocampus shows moderate cytoplasmic positivity in neuronal cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Maus Unkonjugiert IHC, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Maus HRP ICC, IF, IHC, WB Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Clcn3 Monoclonal Antibody, Clone S258-5 . Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Clcn3 Monoclonal Antibody  at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane, Endosome, Endosome membrane, Cytoplasmic Vesicle, Secretory Vesicle Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) Clcn3 Antibody (D) Composite. Western Blot analysis of Rat Brain Membrane showing detection of ~90 kDa CIcn3 protein using Mouse Anti-CIcn3 Monoclonal Antibody, Clone S258-5 . Lane 1: Molecular Weight Ladder. Lane 2: Rat Brain Membrane. Load: 15 µg. Block: 2% BSA and 2% Skim Milk in 1X TBST. Primary Antibody: Mouse Anti-CIcn3 Monoclonal Antibody  at 1:200 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:1000 for 1 hour RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: ~90 kDa. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage

CLCN3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Chloride Channel 3 Antikörper

  1. Mammalian Monoclonal CLCN3 Primary Antibody für WB - ABIN1304600 : Gaurav, Bewtra, Agrawal: Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics. in Immunity, inflammation and disease 2015 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CLCN3 Primary Antibody für IF (p), IHC (p) - ABIN1386131 : Larrouture, Nelson, Robinson, Liu, Tourkova, Schlesinger, Blair: Chloride-hydrogen antiporters ClC-3 and ClC-5 drive osteoblast mineralization and regulate fine-structure bone patterning in vitro. in Physiological reports 2015 (PubMed)

  3. Rat (Rattus) Polyclonal CLCN3 Primary Antibody für WB - ABIN1742509 : Eckenstaler, Lessmann, Brigadski: CAPS1 effects on intragranular pH and regulation of BDNF release from secretory granules in hippocampal neurons. in Journal of cell science 2016 (PubMed)

  4. Cow (Bovine) Polyclonal CLCN3 Primary Antibody für IHC, WB - ABIN2776327 : Salazar, Love, Styers, Werner, Peden, Rodriguez, Gearing, Wainer, Faundez: AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Chloride Channel 3 Interaktionspartner

Human Chloride Channel 3 (CLCN3) Interaktionspartner

  1. ClC-3 is a potential target of 17beta-estradiol and is modulated by the ERalpha (zeige ESR1 Antikörper) in breast cancer cells.

  2. Study provided novel and compelling evidence for the functional role of the unique CLC-3, which are significantly upregulated during ischemia, in the protection of the heart under stress

  3. ClC-3 promotes endometriotic cell migration and invasion.

  4. these results demonstrated that ClC-3 is involved in the proliferation and migration of osteosarcoma cell

  5. Data indicate that cytoplasmic chloride channel-3 (ClC-3) plays an active and key role in tumor metastasis and may be a valuable prognostic biomarker and a therapeutic target to prevent tumor spread.

  6. CLC3 is required in the activation and migration of human blood eosinophils.

  7. Authors summarize the function of CLC-3 in cancer and discuss the mechanisms by which CLC-3 contributes to proliferation, apoptosis and drug resistance in cancer cells. [Review]

  8. swelling-activated Cl currents and CLC-3 play a role in pulmonary artery smooth muscle cell proliferation, but CLC-3 channels do not underlie swelling in these cells

  9. ClC-3 deficiency inhibited Ang II (zeige AGT Antikörper)-induced EPC (zeige TCF21 Antikörper) apoptosis via suppressing ROS (zeige ROS1 Antikörper) generation derived from NADPH oxidase (zeige NOX1 Antikörper).

  10. our data suggest that the ClC-3 chloride channel (zeige CLCA1 Antikörper) is an important target of cyclin D1 (zeige CCND1 Antikörper). Cyclin D1 (zeige CCND1 Antikörper) may regulate the functional activities of the chloride channel (zeige CLCA1 Antikörper) via CDK4 (zeige CDK4 Antikörper) and CDK6 (zeige CDK6 Antikörper), and/or the expression of the chloride channel (zeige CLCA1 Antikörper).

Mouse (Murine) Chloride Channel 3 (CLCN3) Interaktionspartner

  1. Results have shown that the expression of ClC-3 was reduced in hypertrophic H9c2 cells, primary rat neonatal cardiomyocytes and myocardium of C57/BL/6 mice and that ClC-3 played an important role in beta-adrenergic cardiac hypertrophy.

  2. we conclude that the expression of ClC-3 chloride channels in osteoblasts helps them respond to PTH (zeige PTH Antikörper) stimulation, which mediates osteogenic differentiation.

  3. our findings show that Cl(-) channels can be activated by estrogen via ERa on the cell membrane and suggest that the ClC-3 Cl(-) channel may be one of the targets of estrogen in the regulation of osteoblast activity.

  4. ClC-3 is an endogenous inhibitor of neuropathic pain development and down-regulation of ClC-3 contributes to mechanical hypersensitivity.

  5. This study provides a new mechanism by which endophilin A2 (zeige SH3GL1 Antikörper) regulates ClC-3 channel activity, and sheds light on how ClC-3 is transported to cell membranes to play its critical role as a chloride channel (zeige CLCA1 Antikörper) in VSMCs function

  6. roles of AQP-3 (zeige AQP3 Antikörper) in AQP-3 (zeige AQP3 Antikörper) aquaglyceroporin and ClC-3 chloride channels complex

  7. ClC-3 plays a major role in hyperglycemia induced hippocampal neuronal apoptosis.

  8. Threonine532 phosphorylation in ClC-3 channels is required for angiotensin II-induced Cl(-) current and migration in cultured vascular smooth muscle cells

  9. Data suggest that ClC3/Clcn3 expression is up-regulated by mechanical stimulation (persistent static compression here) in osteoblastic cell line and appears to participate in mechanically sensitive osteogenesis and gene expression regulation.

  10. Our findings demonstrated that ClC-3 deficiency inhibits atherosclerotic lesion development, possibly via suppression of JNK (zeige MAPK8 Antikörper)/p38 MAPK (zeige MAPK14 Antikörper) dependent SR-A (zeige MSR1 Antikörper) expression and foam cell formation.

Guinea Pig Chloride Channel 3 (CLCN3) Interaktionspartner

  1. ClC-3 is specialized in mainly performing incomplete capacitive nontransporting cycles in intracellular membranes.

Xenopus laevis Chloride Channel 3 (CLCN3) Interaktionspartner

  1. A local enhancement of CIC (zeige CIC Antikörper)-3 expression at the leading edge of the wounded epidermis was found to be specific to closing wounds.

Chloride Channel 3 (CLCN3) Antigen-Profil

Protein Überblick

This gene encodes a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. This protein plays a role in both acidification and transmitter loading of GABAergic synaptic vesicles, and in smooth muscle cell activation and neointima formation. This protein is required for lysophosphatidic acid (LPA)-activated Cl- current activity and fibroblast-to-myofibroblast differentiation. The protein activity is regulated by Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) in glioma cells. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit CLCN3

  • chloride voltage-gated channel 3 (CLCN3) Antikörper
  • chloride voltage-gated channel 3 (Clcn3) Antikörper
  • chloride channel, voltage-sensitive 3 (Clcn3) Antikörper
  • chloride channel 3 (clcn3) Antikörper
  • H(+)/Cl(-) exchange transporter 5 (LOC5572287) Antikörper
  • chloride channel protein 3 (PTRG_03131) Antikörper
  • chloride channel protein 3 (BDBG_05668) Antikörper
  • chloride channel protein 3 (MCYG_04420) Antikörper
  • chloride channel, voltage-sensitive 3 (clcn3) Antikörper
  • chloride channel, voltage-sensitive 3 S homeolog (clcn3.S) Antikörper
  • clc-3 Antikörper
  • clc3 Antikörper
  • CLCN3 Antikörper
  • fb78c02 Antikörper
  • wu:fb78c02 Antikörper

Bezeichner auf Proteinebene für CLCN3

H(+)/Cl(-) exchange transporter 3 , chloride channel 3 , chloride channel protein 3 , chloride transporter ClC-3 , protein kinase C-regulated chloride channel , clC-3 , chloride channel Clc-3 , Chloride channel protein 3 , H(+)/Cl(-) exchange transporter 3-like , putative chloride channel ClC-3

1182 Homo sapiens
84360 Rattus norvegicus
12725 Mus musculus
422432 Gallus gallus
471346 Pan troglodytes
477354 Canis lupus familiaris
522719 Bos taurus
559340 Danio rerio
5572287 Aedes aegypti
6341356 Pyrenophora tritici-repentis Pt-1C-BFP
8503901 Ajellomyces dermatitidis SLH14081
9229794 Arthroderma otae CBS 113480
100008673 Oryctolagus cuniculus
100021050 Monodelphis domestica
100061225 Equus caballus
100074971 Ornithorhynchus anatinus
100135501 Cavia porcellus
100156049 Sus scrofa
100174300 Pongo abelii
100216107 Xenopus (Silurana) tropicalis
100380301 Salmo salar
100404608 Callithrix jacchus
100581879 Nomascus leucogenys
399089 Xenopus laevis
Ausgewählte Anbieter für anti-Chloride Channel 3 (CLCN3) Antikörper
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