Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
CLCN2 encodes a voltage-gated chloride channel. Zusätzlich bieten wir Ihnen Chloride Channel 2 Antikörper (69) und Chloride Channel 2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Identification and characterization of the zebrafish ClC (zeige CLCF1 ELISA Kits)-2a/b/c chloride channel (zeige CLCA1 ELISA Kits) orthologs.
Genetic ablation of ClC-2 resulted in reduced gastric gland region, reduced parietal cell number, reduced H/K ATPase (zeige ATP4b ELISA Kits), reduced tubulovesicles and reduced stimulated acid secretion.
Data indicate that membrane protein MLC1 is crucial for proper localization of adhesion molecule (zeige NCAM1 ELISA Kits) GlialCAM (zeige HEPACAM ELISA Kits) and chloride channel (zeige CLCA1 ELISA Kits) ClC-2, and for changing ClC-2 currents.
Loss of ClC-2 is associated with increased development of DSS (zeige PMP22 ELISA Kits)-induced colitis.
The PCR data revealed the existence of two astrocytic subpopulations markedly differing in their gene expression levels for inwardly rectifying K+ channels (Kir4.1 (zeige KCNJ10 ELISA Kits)), K(2P) channels (TREK-1 (zeige KCNK2 ELISA Kits) and TWIK-1 (zeige KCNK1 ELISA Kits)) and Cl- channels (ClC2).
ClC-2 channels are required for colonic electroneutral absorption of NaCl and KCl.
permeant Cl(-) ions contribute to V(m)-dependent gating of the broadly distributed ClC-2 Cl() channel.
GABAA (zeige GABRg1 ELISA Kits) receptor-mediated synaptic inputs from basket cells were modulated by ClC-2. Our data reveal a previously unknown cell type-specific regulation of intracellular chloride homeostasis in the perisomatic region of hippocampal pyramidal neurons.
ClC-2 reduces barrier function in normal mucosa. Ultrastructural morphology of tight junctions and myosin light chain kinase (zeige MYLK ELISA Kits) appear to be important to the function of ClC-2 in normal mucosa.
these findings raise the possibility that ClC-2 expression plays a subtle neuroprotective role in the aging hippocampus
Heterozygous nmf240 mice present with a reduced electroretinography light peak component suggests that CLCN2 is necessary for the generation of this response component.
ClC-2-mediated intestinal Cl - secretion restores transepithelial resistance in ischemia-injured intestine.
The findings show that RGET691 of human ClC-2 (possible binding site) plays an important functional role in fatty acid activation of human ClC-2.
Hyperpolarization activates CLC-2 mainly by driving intracellular anions into the channel pores.
The extracellular domain of GlialCAM (zeige HEPACAM ELISA Kits) is necessary for cell junction targeting and for mediating interactions with itself or with MLC1 and ClC-2.
both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 (zeige FOSB ELISA Kits) are capable of carrying out basolateral sorting of ClC-2.
SPAK (zeige STK39 ELISA Kits) and OSR1 (zeige OXSR1 ELISA Kits) are powerful negative regulators of the cell volume regulatory Cl- channel ClC-2
Correlation between CLC-2 gene expression and the cytoskeleton in human trabecular meshwork cells.
Our observations substantiate the concept that ClC-2 is involved in brain ion and water homoeostasis
JAK2 (zeige JAK2 ELISA Kits) down-regulates ClC-2 activity and thus counteracts Cl(-) exit, an effect which may impact on cell volume regulation
This study demonistrated that the first auxiliary subunit of ClC-2 and suggests that ClC-2 may play a role in the pathology of MLC disease.
ClC-2 plays an important role in the modulation of tight junctions by influencing caveolar trafficking of tight junction protein occludin (zeige OCLN ELISA Kits).
This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
chloride channel 2
, novel protein similar to vertebrate chloride channel 2 (CLCN2)
, chloride channel protein 2
, PKA-activated chloride channel ClC-2G