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The protein encoded by CHI3L2 is similar to bacterial chitinases but lacks chitinase activity. Zusätzlich bieten wir Ihnen Chitinase 3-Like 2 Antikörper (74) und Chitinase 3-Like 2 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.
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This study suggests that CHI3L1 (zeige CHI3L1 Proteine) and CHI3L2 are associated with the progression of neurodegeneration in motor cortex and spinal cord of Amyotrophic Lateral Sclerosis patients.
This study shown that CHI3L2 is regulated differently in healthy and late onset Alzheimer"s disease brain depending on the sex.
This review comprehensively analyzes recent data about expression pattern, and involvement of human YKL-40 (zeige CHI3L1 Proteine), YKL-39 and SI-CLP (zeige CHID1 Proteine) in cancer. [review]
cerebrospinal fluid CHI3L1 (zeige CHI3L1 Proteine) and CHI3L2 and serum CHI3L1 (zeige CHI3L1 Proteine) might help to define multiple sclerosis disease stage
Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy.
YKL-39 possesses a chitinase-like fold, but lacks key active-site residues required for catalysis.
ERK1/2 phosphorylation by CHI3L2 inhibits cell mitogenesis and proliferation.
human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40 (zeige CHI3L1 Proteine)) is upregulated in osteoarthritic cartilage
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene.
chitinase-3-like protein 2
, chondrocyte protein 39