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The protein encoded by CCR3 is a receptor for C-C type chemokines. Zusätzlich bieten wir Ihnen CCR3 Antikörper (340) und CCR3 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
, C-C chemokine receptor type 3
, CC chemokine receptor 3
, b-chemokine receptor
, eosinophil CC chemokine receptor 3
, eosinophil eotaxin receptor
, MIP-1 alpha RL2
, MIP-1 alphaRL2
, chemokine (C-C) receptor 1,-like 2
, chemokine (C-C) receptor 3
, macrophage inflammatory protein 1-alpha receptor-like 2
, probable C-C chemokine receptor type 3
, C-C chemokine receptor 3
, eotaxin receptor CCR3