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The protein encoded by CEND1 is a neuron-specific protein. Zusätzlich bieten wir Ihnen Cell Cycle Exit and Neuronal Differentiation 1 Proteine (7) und und viele weitere Produktgruppen zu diesem Protein an.
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BM88/Cend1 participates in cell cycle control and neuronal differentiation mechanisms during neonatal SVZ neurogenesis and becomes crucial for the transition from neuroblasts to mature neurons when reaching high levels
data suggest that common reprogramming mechanisms exist driving the conversion of lineage-distant somatic cell types to neurons and reveal a critical role for CEND1 in NEUROG2 (zeige NEUROG2 Antikörper)-driven astrocytic reprogramming.
results suggest that functional interactions between BM88/Cend1, RanBPM and Dyrk1B (zeige DYRK1B Antikörper) affect the balance between cellular proliferation and differentiation in Neuro 2a cells
This study suggested that Cend1 is involved in Ahi1 (zeige AHI1 Antikörper)-associated hypothalamic neuronal differentiation in early development, giving us fresh insight into the mechanism behind the delayed development in Joubert syndrome.
Our results suggest that Cend1 is required for normal cerebellar development.
Transplantation of BM88/Cend1-overexpressing neural progenitor cells exerts beneficial effects on tissue regeneration by enhancing the number of generated neurons and restricting the formation of astroglial scar, in a mouse model of cortical brain injury.
BM88 is widely expressed in the embryonic CNS and PNS, in both nestin (zeige NES Antikörper)-positive neuroepithelial cells and post-mitotic betaIII-tubulin (zeige TUBB3 Antikörper) positive neurons.
Results implicate BM88 in the synchronization of cell cycle exit and differentiation of neuronal precursors in the developing nervous system.
BM88 plays an essential role in regulating cell cycle exit and differentiation of Neuro 2a cells toward a neuronal phenotype
The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene.
, cell cycle exit and neuronal differentiation protein 1
, cell cycle exit and neuronal differentiation 1