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Involved in the cell-cell adhesion.
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Cell adhesion molecule 4 (cadm4) is essential for restricting the size of the zebrafish cardiac outflow tract.
There was a significant association between RNase 5 (zeige ANG ELISA Kits) and histological differentiation in colon adenocarcinomas, but no association between RNase 5 (zeige ANG ELISA Kits) and Necl 4 in gastric or colon adenocarcinomas
Low CADM4 expression is associated with bone marrow metastasis in neuroblastoma.
The results suggest that Necl-4 enhances VEGF (zeige VEGFA ELISA Kits)-induced activation of PLCgamma-c-Raf (zeige RAF1 ELISA Kits)-MEK (zeige MAP2K1 ELISA Kits)-ERK (zeige EPHB2 ELISA Kits) pathway without affecting the phosphorylation and internalization of VEGFR2 (zeige KDR ELISA Kits).
Necl-4 serves as a novel regulator for contact inhibition of cell movement and proliferation cooperatively with the VEGF receptor and PTPN13
results indicate that Necl-4 serves as a tumor suppressor by inhibiting the ErbB2 (zeige ERBB2 ELISA Kits)/ErbB3 (zeige ERBB3 ELISA Kits) signaling and hemidesmosome disassembly
Loss or decrease of CADM4 expression seems to play an important role in breast cancer invasiveness, and it is associated with poorer biological parameters.
Cadm4 regulates the growth of the myelin unit and the organization of the underlying axonal membrane.
CADM4, as well as 4.1B (zeige EPB41L3 ELISA Kits) is expressed specifically in human proximal tubules.
TSLL2 is expressed at the cell-cell attachment sites in the renal tubules, the transitional epithelia of the bladder, and the glandular epithelia of the prostate, and is a tumor-suppressor candidate in prostate cancer.
Necl-4 is dispensable for axonal myelination in the developing nervous system.
findings imply that 4.1G plays a role in spermatogenesis by mediating cell-cell adhesion between spermatogenic and Sertoli cells through its interaction with NECL4 on Sertoli cells
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor- suppressor activity (By similarity).
cell adhesion molecule 4
, immunoglobulin superfamily, member 4C
, cell adhesion molecule 4-like
, TSLC1-like 2
, TSLC1-like protein 2
, immunoglobulin superfamily member 4C
, nectin-like 4
, nectin-like protein 4
, SynCAM 4
, membrane glycoprotein Tsll2
, urokinase plasminogen activator receptor