Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
STS1 encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. Zusätzlich bieten wir Ihnen Cbl-Interacting Protein Sts-1 Antikörper (26) und Cbl-Interacting Protein Sts-1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Data suggest that Sts1 (suppressor of T-cell receptor signaling-1) negatively regulates TCR (T-cell receptor) signaling in activated T-lymphocytes via dephosphorylation of ZAP70 (zeige ZAP70 ELISA Kits).
The results show that the interaction between STS-1 and ShcA (zeige SHC1 ELISA Kits) is regulated in response to EGF receptor (zeige EGFR ELISA Kits) activation.
The study reveals a role of CBL (zeige CBL ELISA Kits) in restricting myeloid proliferation of human AML1 (zeige RUNX1 ELISA Kits)-ETOinduced leukemia, and identifies UBASH3B as a potential target for pharmaceutical intervention.
targeting Aurora B (zeige AURKB ELISA Kits) to microtubules by UBASH3B is necessary for the timing and fidelity of chromosome segregation in human cells
These results show that TULA-2 is a target of miR (zeige MLXIP ELISA Kits)-148a-3p
This recovery involves the phosphorylation of p70 (zeige ANXA6 ELISA Kits) independent of mTOR (zeige FRAP1 ELISA Kits).
results demonstrate the importance of STS-1 in regulating IFN-alpha (zeige IFNA ELISA Kits)-induced autophagy in B cells
UBASH3B is a functional target of anti-invasive microRNA200a that is down-regulated in triple negative breast cancer. Importantly, the oncogenic potential of UBASH3B is dependent on its tyrosine phosphatase activity.
Ablation of TULA-2 resulted in hyperphosphorylation of Syk (zeige SYK ELISA Kits) and its downstream effector phospholipase C (zeige PLC ELISA Kits)-gamma2 as well as enhanced GPVI (zeige GP6 ELISA Kits)-mediated platelet functional responses.
Sts-1 and Sts-2 bind to Cbl (zeige CBL ELISA Kits) and inhibit endocytosis of receptor tyrosine kinases
Data suggest that Sts1 (suppressor of T-cell receptor signaling-1) negatively regulates TCR (T-cell receptor) signaling in activated T-lymphocytes via dephosphorylation of Zap70 (zeige ZAP70 ELISA Kits).
Sts-1 and Sts-2 are not required for the immune control of murine herpesvirus 68 in a normal course of gammaherpesvirus infection.
The absence of TULA-2 and also the relative level of TULA-2 expression modulates FcgammaRIIA-mediated platelet reactivity and heparin-induced thrombocytopenia in vivo.
dephosphorylation of Tyr (zeige TYR ELISA Kits)(P)(346) may be considered an important "checkpoint" in the regulation of Syk (zeige SYK ELISA Kits) activation process. Putative biological functions of TULA-2-mediated dephosphorylation of Tyr (zeige TYR ELISA Kits)(P)(346) may include deactivation of receptor-activated Syk (zeige SYK ELISA Kits) or suppression of Syk (zeige SYK ELISA Kits) activation by suboptimal stimulation.
Biochemical analysis identified STS-1 and STS-2 as direct phosphatases of FLT3 (zeige FLT3 ELISA Kits) and c-KIT (zeige KIT ELISA Kits).
results demonstrate the importance of STS-1 in regulating IFN-alpha (zeige IFNA ELISA Kits)-induced autophagy in B cells.
The lack of TULA-2 facilitates T-cell responses to TCR/CD3 (zeige CD3E ELISA Kits) stimulation, thus exacerbating T-cell-dependent inflammation.
TULA-2 negatively regulates osteoclast differentiation and function.
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase (zeige YES1 ELISA Kits) Syk (zeige SYK ELISA Kits) interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.
This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
Cbl-interacting protein Sts-1
, SH3 domain-containing 70 kDa protein, suppressor of T-cell receptor signaling 1, nm23-phosphorylated unknown substrate
, T-cell ubiquitin ligand 2
, cbl-interacting protein p70
, nm23-phosphorylated unknown substrate
, suppressor of T-cell receptor signaling 1
, tyrosine-protein phosphatase STS1/TULA2
, ubiquitin-associated and SH3 domain-containing protein B