anti-Cbl Proto-Oncogene-Like 1, E3 Ubiquitin Protein Ligase (CBLL1) Antikörper

CBLL1 encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes.

Alle Antikörper anzeigen Gen GeneID UniProt
CBLL1 79872 Q75N03
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Top anti-Cbl Proto-Oncogene-Like 1, E3 Ubiquitin Protein Ligase Antikörper auf antikoerper-online.de

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$675.71
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Human Kaninchen Unkonjugiert IF, IHC, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$856.43
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$240.90
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Human Kaninchen Unkonjugiert IHC (fro), IF, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
$565.10
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CBLL1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human


Am meisten referenzierte anti-Cbl Proto-Oncogene-Like 1, E3 Ubiquitin Protein Ligase Antikörper

  1. Human Polyclonal CBLL1 Primary Antibody für IHC (fro), IF - ABIN2192196 : Fujita, Krause, Scheffner, Zechner, Leddy, Behrens, Sommer, Birchmeier: Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. in Nature cell biology 2002 (PubMed)

Weitere Antikörper gegen Cbl Proto-Oncogene-Like 1, E3 Ubiquitin Protein Ligase Interaktionspartner

Human Cbl Proto-Oncogene-Like 1, E3 Ubiquitin Protein Ligase (CBLL1) Interaktionspartner

  1. These results suggest that stabilization of delta-catenin (zeige CTNND2 Antikörper) by Hakai is dependent on Src (zeige SRC Antikörper).

  2. these observations suggest that the dimeric architecture of the HYB domain is essential for the phosphotyrosine-binding property of Hakai.

  3. By lowering Hakai abundance, miR (zeige MLXIP Antikörper)-203 also reduces Hakai-regulated-cell division.

  4. Hakai dimerization allows the formation of a phosphotyrosine-binding pocket that recognizes specific phosphorylated tyrosines and flanking acidic amino acids of Src (zeige SRC Antikörper) substrates, such as E-cadherin (zeige CDH1 Antikörper), cortactin (zeige CTTN Antikörper) and DOK1 (zeige DOK1 Antikörper).

  5. Hakai mediates E-cadherin (zeige CDH1 Antikörper) ubiquitination and degradation triggered by Slit-Robo signaling during colorectal epithelial cell carcinogenesis.

  6. Together, these data do not support a requirement for CBLL1 during flavivirus entry and rather suggest an essential role of the ubiquitin/proteasome pathway for flavivirus genome amplification.

  7. Results suggest that Hakai is a novel corepressor of ERalpha (zeige ESR1 Antikörper) and may play a negative role in the development and progression of breast cancers.

  8. Results suggest that Hakai is an important regulator of cell proliferation and that Hakai may be an oncoprotein and a potential molecular target for cancer treatment.

Cbl Proto-Oncogene-Like 1, E3 Ubiquitin Protein Ligase (CBLL1) Antigen-Profil

Protein Überblick

This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant.

Genbezeichner und Symbole assoziert mit CBLL1

  • Cbl proto-oncogene like 1 (CBLL1) Antikörper
  • HAKAI Antikörper
  • RNF188 Antikörper

Bezeichner auf Proteinebene für CBLL1

Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 , Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1 , E-cadherin binding protein E7 , E3 ubiquitin-protein ligase Hakai , RING finger protein 188 , c-Cbl-like protein 1 , casitas B-lineage lymphoma-transforming sequence-like protein 1

GENE ID SPEZIES
79872 Homo sapiens
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