Cathepsin E Proteine (CTSE)

The protein encoded by CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. Zusätzlich bieten wir Ihnen Cathepsin E Antikörper (67) und Cathepsin E Kits (16) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CTSE 1510 P14091
CTSE 13034 P70269
CTSE 25424 P16228
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Showing 10 out of 22 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
HEK-293 Cells Human His tag Human Cathepsin E, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$346.50
Details
Escherichia coli (E. coli) Human Unkonjugiert 25 μg Anmelden zum Anzeigen 10 bis 12 Tage
$470.28
Details
Human Cells Maus His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Hefe REACT_Bullfrog His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,946.17
Details
HEK-293 Cells Human His tag   0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
$618.75
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$295.00
Details
HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 12 bis 15 Tage
$504.74
Details
Mammalian Cells Maus His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
Details

CTSE Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) ,

Weitere Proteine zu Cathepsin E (CTSE) Interaktionspartnern

Human Cathepsin E (CTSE) Interaktionspartner

  1. Cathepsin E, mitochondrial fission, and caspase (zeige CASP3 Proteine) activation/apoptosis are linked in the pathogenesis of pulmonary emphysema.

  2. High Expression of Cathepsin E is associated with Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma.

  3. Decreased activity of cathepsin E produced by decidual macrophages might be responsible for the induction of miscarriages in some recurrent miscarriage patients.

  4. data demonstrate that CatE contributes to normal growth and development of mammary glands through proper trafficking and secretion of Wnt5a (zeige WNT5A Proteine)

  5. CTSE is a marker of both gastric differentiation and signet-ring cell carcinoma, which should shed light on the mechanism of gastric tumorigenesis.

  6. A comparative structure model of splice variant 2 was computed based on its alignment to the known structure of cathepsin E intermediate (Protein Data Bank code 1TZS) and used to rationalize its conformational properties and loss of activity.

  7. Emerging roles of cathepsin E in immune system cells and skin keratinocytes, and in host defense against cancer cells.

  8. These results suggest the possible involvement of cathepsin E in disruption of the structural and functional integrity of alpha 2-macroglobulin (zeige A2M Proteine) in the endolysosome system.

  9. Reduced expression of cathepsin E is observed in erythrocytes of humans with atopic dermatitis.

  10. crystal structure of an activation intermediate of cathepsin E at 2.35A resolution

Mouse (Murine) Cathepsin E (CTSE) Interaktionspartner

  1. Cathepsin E, mitochondrial fission, and caspase (zeige CASP3 Proteine) activation/apoptosis are linked in the pathogenesis of pulmonary emphysema.

  2. These results indicate that cathepsin E deficiency causes autophagy impairment concomitantly with increased aberrant mitochondria as well as increased oxidative stress.

  3. impaired adipose tissue development in high fat diet-induced CatE(-/-) mice was probably due to reduced infiltration of macrophages and may lead to hepatomegaly accompanied by hepatic steatosis and hypercholesterolemia

  4. L1 stimulation triggers sumoylation and cleavage of L1, thus generating the L1-70 fragment which is cleaved by cathepsin E

  5. Intradermal cathepsin E has pruritogenic activity, which is at least partly mediated by the production of endothelin-1 (zeige EDN1 Proteine).

  6. Low expression levels of MHC class II and cathepsin E might contribute to the defect in induction of Ag-specific T cells in NC mice.

  7. Results suggest that Sp1 (zeige SP1 Proteine) binding plays a particularly important role in the regulation of cathepsin E gene expression.

  8. the findings suggest that in keratinocytes CatE is functionally linked to the expression of terminal differentiation markers, thereby regulating epidermis formation and homeostasis.

  9. Development of atopic dermatitis in cathepsin E-deficient mouse model is initiated by systemic accumulation of interleukin (IL)-18 (zeige IL18 Proteine) and IL-1 beta (zeige IL1B Proteine), mainly due to their reduced turnover rates.

  10. Cathepsin E is expressed in mice myeloid dendritic cells, where it has an important nonredundant role in the class II major histocompatibility complex antigen processing pathway.

Cathepsin E (CTSE) Protein Überblick

Protein Überblick

The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

Genbezeichner und Symbole assoziert mit Cathepsin E Proteine (CTSE)

  • cathepsin E (CTSE)
  • cathepsin E (TP03_0056)
  • cathepsin E (Smp_184930)
  • cathepsin E (ctse)
  • hypothetical protein (PGTG_08035)
  • cathepsin E (Ctse)
  • A430072O03Rik Protein
  • C920004C08Rik Protein
  • CatE Protein
  • CE Protein
  • ce1 Protein
  • ce2 Protein
  • CEA Protein
  • CEB Protein
  • CTSE Protein
  • Ctsea Protein

Bezeichner auf Proteinebene für Cathepsin E Proteine (CTSE)

cathepsin E , erythrocyte membrane aspartic proteinase , slow-moving proteinase , procathepsin E

GENE ID SPEZIES
100055161 Equus caballus
457677 Pan troglodytes
488577 Canis lupus familiaris
696202 Macaca mulatta
771791 Gallus gallus
3500391 Theileria parva strain Muguga
8353731 Schistosoma mansoni
100145572 Xenopus (Silurana) tropicalis
100413525 Callithrix jacchus
10533656 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100603573 Nomascus leucogenys
1510 Homo sapiens
13034 Mus musculus
25424 Rattus norvegicus
100135509 Cavia porcellus
100009063 Oryctolagus cuniculus
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