Caspase Recruitment Domain Family, Member 14 (CARD14) ELISA Kits

CARD14 encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Zusätzlich bieten wir Ihnen CARD14 Antikörper (52) und CARD14 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human CARD14 CARD14 79092 Q9BXL6
Anti-Maus CARD14 CARD14 170720 Q99KF0
Anti-Ratte CARD14 CARD14 688292  
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Weitere ELISA Kits für CARD14 Interaktionspartner

Human Caspase Recruitment Domain Family, Member 14 (CARD14) Interaktionspartner

  1. The serine/threonine kinase (zeige TLK2 ELISA Kits) ULK2 (zeige ULK2 ELISA Kits) binds to and phosphorylates CARMA2sh.

  2. MALT1 (zeige MALT1 ELISA Kits) deficiency or pharmacological inhibition of MALT1 (zeige MALT1 ELISA Kits) catalytic activity inhibits pathogenic mutant CARD14-induced cytokine and chemokine (zeige CCL1 ELISA Kits) expression in human primary keratinocytes.

  3. CARD14/MALT1 (zeige MALT1 ELISA Kits)-mediated signaling in keratinocytes has a role in psoriasis [review]

  4. The results indicate that the common CARD14 p.Arg820Trp variant might have a significant effect on the response to anti-TNF (zeige TNF ELISA Kits) therapies among patients with psoriasis. In addition, rare CARD14 missense variants could also predispose to a better response.

  5. Our findings, combined with the published literature, suggest that Pityriasis Rubra Pilaris Type V, both familial and sporadic, can be caused by CARD14 mutations.

  6. Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10 (zeige BCL10 ELISA Kits)-MALT1 (zeige MALT1 ELISA Kits)-dependent NF-kappaB (zeige NFKB1 ELISA Kits) activation

  7. genetic evidence suggests association of the CARD14 single nucleotide polymorphism rs11652075 and other rare mutations in this gene with psoriasis. To assess whether combined data support the relationship between CARD14 rs11652075 and susceptibility to this disease, we conducted a meta-analysis. Our results demonstrate a significant association between the CARD14 rs11652075 polymorphism and psoriasis.

  8. The authors observations provide further insights into the genetics of psoriasis and functional information on novel CARD14 mutational variants seen in cases from Tunisia and other populations.

  9. Genetic interactions of SNPs in CARD14, SENP1 (zeige SENP1 ELISA Kits) and VEGFA (zeige VEGFA ELISA Kits) might represent a functional mechanism in the pathogenesis of high altitude polycythemia.

  10. analysis of 105 individuals with generalized pustular psoriasis (GPP) identified a low-frequency variant (p.Asp176His) that causes constitutive CARD14 oligomerization

CARD14 Antigen-Profil

Beschreibung des Gens

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit CARD14

  • caspase recruitment domain family member 14 (CARD14) Antikörper
  • caspase recruitment domain family, member 14 (Card14) Antikörper
  • Bimp2 Antikörper
  • CARMA2 Antikörper
  • PRP Antikörper
  • PSORS2 Antikörper
  • PSS1 Antikörper

Bezeichner auf Proteinebene für CARD14

CARD-containing MAGUK protein 2 , bcl10-interacting maguk protein 2 , card-maguk protein 2 , carma 2 , caspase recruitment domain-containing protein 14 , bcl10-interacting MAGUK protein 2

GENE ID SPEZIES
79092 Homo sapiens
170720 Mus musculus
688292 Rattus norvegicus
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