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Involved in the activation cascade of caspases responsible for apoptosis execution (By similarity). Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Jin, Strich, Cooper: Slt2p phosphorylation induces cyclin C nuclear-to-cytoplasmic translocation in response to oxidative stress. in Molecular biology of the cell 2014
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Lopez, Kelleher: Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells. in Experimental cell research 2010
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Gugliesi, De Andrea, Mondini, Cappello, Giovarelli, Shoenfeld, Meroni, Gariglio, Landolfo: The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity. in Journal of autoimmunity 2010
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drICE and dcp-1 function in cell death redundantly. However, dying neurons in a few clusters strictly required drICE but not dcp-1, but required drICE and dcp-1 when drICE activity was reduced via hypomorphic mutation.
Drosophila corazonin-producing interneuron programmed cell death utilizes dronc, strica, dcp-1, and ice
Autophagy suppresses Dcp-1-mediated apoptotic cell death, whereas Dcp-1 positively regulates autophagy, possibly through feedback regulation.
novel characteristic morphological features of egg chambers lacking both dcp-1 and pita functions in the germline cells; suggested an essential role of dcp-1 and/or pita during mid-oogenesis
A double-mutant analysis between drICE and death caspase-1 (dcp-1), another effector caspase, reveals that some cells (type I) strictly require drICE for apoptosis, whereas other cells (type II) require either drICE or dcp-1.
Data show that the effector caspase Dcp-1 and the inhibitor of apoptosis protein Bruce function to regulate both autophagy and starvation-induced cell death in Drosophila.
HeT-A mRNA is derepressed in mRNA degradation mutants dcp1, indicating that the enzyme also aid in removing full-length transcripts and/or decay intermediates.
Involved in the activation cascade of caspases responsible for apoptosis execution (By similarity). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Loss of zygotic DCP-1 function causes larval lethality and melanotic tumors.
, caspase 1
, death caspase-1