Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteine (CEACAM1)

CEACAM1 encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily.

alle Proteine anzeigen Gen GeneID UniProt
Human CEACAM1 CEACAM1 634 P13688
Ratte CEACAM1 CEACAM1 81613 P16573
Maus CEACAM1 CEACAM1 26365 P31809
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Top Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) Proteine auf antikoerper-online.de

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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human Fc Tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
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Human Cells Human His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,649.05
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
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Human Cells Maus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
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Human Cells Ratte His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
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Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$280.50
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HEK-293 Cells Human His tag Human CEACAM-1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$275.00
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HEK-293 Cells Human Unkonjugiert   10 μg Anmelden zum Anzeigen 2 bis 3 Tage
$175.00
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HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
$394.90
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Weitere Proteine zu Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Interaktionspartnern

Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Interaktionspartner

  1. these data identify CEACAM1 as a clinically highly interesting target in multiple sclerosis pathogenesis and open new therapeutic avenues for the treatment of the disease.

  2. serum levels of CEACAM1 in healthy pregnant women were much lower than in non-pregnant women

  3. CEACAM1 overexpression significantly suppressed MM cell proliferation, induced cell apoptosis, and inhibited cell invasion and migration possibly through activation of caspase-3 (zeige CASP3 Proteine) and downregulation of MMP-2 (zeige MMP2 Proteine) and MMP-9 (zeige MMP9 Proteine).

  4. Data suggest that the serum level of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) may be used to discriminate gastrointestinal cancer patients from health controls.

  5. In this paper, a dual-target electrochemical aptasensor has been developed for simultaneous detection of carcinoembryonic antigen (zeige CEACAM5 Proteine) and mucin-1 (zeige MUC1 Proteine) based on metal ion electrochemical labels and Ru(NH3)6(3+) electronic wires

  6. Furthermore, the proposed aptasensor was successfully applied in determining CEA (zeige CEACAM5 Proteine) in serum samples, showing its superior prospects in clinical diagnosis.

  7. we show here that Human Metapneumovirus (HMPV)-infected cells upregulates CEACAM1 to restrict HMPV infection

  8. Helicobacter pylori HopQ binds the amino-terminal IgV-like domain of human CEACAM1, CEACAM3 (zeige CEACAM3 Proteine), CEACAM5 (zeige CEACAM5 Proteine) or CEACAM6 proteins, thereby enabling translocation of the major pathogenicity factor CagA (zeige S100A8 Proteine) into host cells.

  9. Here, the authors identify members of the carcinoembryonic antigen (zeige CEACAM5 Proteine)-related cell adhesion molecule (zeige MCAM Proteine) (CEACAM) family as receptors of Helicobacter pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CEACAM1, CEACAM3 (zeige CEACAM3 Proteine), CEACAM5 (zeige CEACAM5 Proteine) and CEACAM6.

  10. Data show that SOX9 (zeige SOX9 Proteine) regulates CEACAM1 primarily via Sp1 (zeige PSG1 Proteine) and ETS1 (zeige ETS1 Proteine).

Mouse (Murine) Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Interaktionspartner

  1. CEACAM1 controls epithelial-mesenchymal transition in vitro and in vivo by site-specific regulation of beta-catenin (zeige CTNNB1 Proteine) phosphorylation

  2. A 30-day high fat feeding regimen demonstrated that white adipose tissue-derived fatty acids repressed hepatic CEACAM1-dependent regulation of insulin (zeige INS Proteine) and lipid metabolism in 3-month-old male C57BL/6J mice.

  3. REVIEW: summarizes the vascular effects of CEACAM1 and focuses on its role in vascular morphogenesis and endothelial barrier regulation

  4. CEACAM1 exacerbates hypoxic cardiomyocyte injury and post-infarction cardiac remodeling by enhancing cardiomyocyte mitochondrial dysfunction and endoplasmic reticulum stress-induced apoptosis.

  5. The increase in total fat mass in Cc1(-/-) mice is mainly attributed to hyperphagia and reduced spontaneous physical activity. Although the contribution of the loss of CEACAM1 from anorexigenic proopiomelanocortin (zeige POMC Proteine) neurons in the arcuate nucleus is unclear, leptin (zeige LEP Proteine) resistance and elevated hypothalamic fatty-acid synthase (zeige FASN Proteine) activity could underlie altered energy balance in these mice.

  6. Ceacam1 is essential for normal integrin aIIbb3-mediated platelet function; the disruption of mouse Ceacam1 induced moderate integrin aIIbb3-mediated functional defects.

  7. hepatic CEACAM1 expression at fasting is mediated by Pparalpha (zeige PPARA Proteine)-dependent mechanisms.

  8. Gram-positive bacteria promote the mRNA expression of CEACAM1 or CEACAM20 in the small intestine. Inflammatory cytokines or butyrate likely participates in such effects of commensal bacteria.

  9. CEACAM1 is a crucial regulator of B-cell survival, influencing B-cell numbers and protective antiviral antibody responses

  10. High-fat diet amplifies the permissive effect of Ceacam1 deletion on renal expression of all renin (zeige REN Proteine)-angiotensin system components, PI3K phosphorylation, inflammation, and fibrosis.

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (Biliary Glycoprotein) (CEACAM1) Protein Überblick

Protein Überblick

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Genbezeichner und Symbole assoziert mit CEACAM1

  • carcinoembryonic antigen related cell adhesion molecule 1 (CEACAM1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (ceacam1)
  • carcinoembryonic antigen related cell adhesion molecule 1 (Ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 1 (Ceacam1)
  • carcinoembryonic antigen-related cell adhesion molecule 6 (LOC101103343)
  • bb-1 Protein
  • Bgp Protein
  • Bgp1 Protein
  • BGPI Protein
  • BGPR Protein
  • C-CAM Protein
  • Cc1 Protein
  • Ccam1 Protein
  • CD66a Protein
  • Cea-1 Protein
  • Cea-7 Protein
  • Cea1 Protein
  • Cea7 Protein
  • CEACAM1 Protein
  • hm:zeh0068 Protein
  • Hv-2 Protein
  • Hv2 Protein
  • mCEA1 Protein
  • Mhv-1 Protein
  • MHVR Protein
  • MHVR1 Protein
  • mmCGM1 Protein
  • mmCGM1a Protein
  • mmCGM2 Protein
  • zeh0068 Protein

Bezeichner auf Proteinebene für CEACAM1

CD66a antigen , antigen CD66 , carcinoembryonic antigen-related cell adhesion molecule 1 , ATP-dependent taurocolate-carrier protein , C-CAM 105 , CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin) , GP110 , bone gamma-carboxyglutamic acid (Gla) protein , cell-CAM 105 , ecto-ATPase , osteocalcin , pp120 , pp120/ecto-ATPase , BGP-1 , CEA-related cell adhesion molecule 1 , MHV-R , biliary glycoprotein 1 , biliary glycoprotein D , carcinoembryonic antigen 1 , carcinoembryonic antigen 7 , hepatitis virus (MHV-4) susceptibility , hepatitis virus receptor , murine hepatitis virus receptor , carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) , carcinoembryonic antigen-related cell adhesion molecule 6

GENE ID SPEZIES
634 Homo sapiens
114465 Danio rerio
612435 Canis lupus familiaris
81613 Rattus norvegicus
26365 Mus musculus
101103343 Ovis aries
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