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The protein encoded by CACNG7 is a type II transmembrane AMPA receptor regulatory protein (TARP).
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Human Polyclonal CACNG7 Primary Antibody für IP - ABIN528386
Zonouzi, Renzi, Farrant, Cull-Candy: Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells. in Nature neuroscience 2011
The results of this study suggested that TARPed synaptic receptors in granule cells require both gamma-2 and gamma-7 and reveal an unexpected basis for the loss of AMPAR-mediated transmission in stargazer (zeige CACNG2 Antikörper) mice.
Results suggest that TARPs (zeige RBM10 Antikörper) gamma-2 and gamma-7 cooperatively promote synaptic expression of cerebellar AMPA (zeige GRIA3 Antikörper) receptors, and the latter also promotes glial expression.
TARP gamma-7 causes AMPA (zeige GRIA3 Antikörper) receptors to "resensitize" upon continued glutamate (zeige GRIN1 Antikörper) application.
Gamma-7 is a new member of the transmembrane AMPA (zeige GRIA3 Antikörper) receptor regulatory protein (zeige TGFB1 Antikörper) (TARP (zeige TINAGL1 Antikörper)) family that can differentially influence AMPA (zeige GRIA3 Antikörper) receptors in cerebellar neurons. (TARP gamma-7)
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit.
calcium channel, voltage-dependent, gamma subunit 5
, calcium channel, voltage-dependent, gamma subunit 7
, voltage-dependent calcium channel gamma-7 subunit
, TARP gamma-7
, neuronal voltage-gated calcium channel gamma-7 subunit
, transmembrane AMPAR regulatory protein gamma-7
, voltage dependent calcium channel gamma 7 subunit