anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Antikörper

CACNA2D1 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human CACNA2D1 CACNA2D1 781 P54289
Anti-Maus CACNA2D1 CACNA2D1 12293 O08532
Anti-Ratte CACNA2D1 CACNA2D1 25399  
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Top anti-CACNA2D1 Antikörper auf antikoerper-online.de

Showing 10 out of 78 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Meerschweinchen Maus Unkonjugiert FACS, ICC, IF, IHC, IHC (fro), IHC (p), WB Immunocytochemistry/Immunofluorescence: CACNA2D1 Antibody (20A) [ABIN266954] - Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Dihydropyridine Receptor alpha-2 monoclonal antibody at a dilution of 1:100 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody and nuclei with DAPI (blue) is shown. Flow Cytometry: CACNA2D1 Antibody (20A) [ABIN266954] - Analysis of C6 cells compared to an isotype control (blue). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  CACNA2D1  Sample Type:  Fetal Muscle  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  1ug/ml  Peptide Concentration:  5ug/ml  Lysate Quantity:  25ug/lane/Lane  Gel Concentration:  0.12 WB Suggested Anti-CACNA2D1 Antibody Titration:  0.12ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN190770 (0.03µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: CACNA2D1 Antibody [NBP1-86683] - Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Immunohistochemistry-Paraffin: CACNA2D1 Antibody  - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB Skeletal muscle 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Kaninchen Unkonjugiert FACS, WB Western blot analysis of CACNA2D1 Antibody (N-term) (ABIN652644) in mouse brain tissue lysates (35 µg/lane). CACNA2D1 (arrow) was detected using the purified polyclonal antibody. CACNA2D1 Antibody (N-term) (ABIN652644) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, WB AP17917PU-N CACNA2D1 Antibody (N-term) Flow Cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis of CACNA2D1 Antibody (N-term) in mouse brain tissue lysates (35ug/lane). CACNA2D1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert ELISA, WB Immunohistochemistry: CACNA2D1 Antibody [ABIN253173] - ABIN253173 (0.03ug/ml) staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: CACNA2D1 Antibody [ABIN2531731] - Analysis of CACNA2D1 using this antibody at 0.03ug/ml in human brain (cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$462.00
Details

Am meisten referenzierte anti-CACNA2D1 Antikörper

  1. Guinea Pig Monoclonal CACNA2D1 Primary Antibody für FACS, ICC - ABIN266954 : Rasmussen, Møller, Knaus, Jensen, Olesen, Jørgensen: Subcellular localization of the delayed rectifier K(+) channels KCNQ1 and ERG1 in the rat heart. in American journal of physiology. Heart and circulatory physiology 2004 (PubMed)
    Show all 8 Pubmed References

  2. Cow (Bovine) Polyclonal CACNA2D1 Primary Antibody für WB - ABIN2776091 : Stotz, Barr, McRory, Chen, Jarvis, Zamponi: Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal CACNA2D1 Primary Antibody für ELISA, WB - ABIN253173 : Neely, Hess, Costigan, Keene, Goulas, Langeslag, Griffin, Belfer, Dai, Smith, Diatchenko, Gupta, Xia, Amann, Kreitz, Heindl-Erdmann, Wolz, Ly, Arora, Sarangi, Dan, Novatchkova, Rosenzweig, Gibson et al.: A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. ... in Cell 2010 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal CACNA2D1 Primary Antibody für ELISA, WB - ABIN190770 : Hullin, Matthes, von Vietinghoff, Bodi, Rubio, DSouza, Friedrich Khan, Rottländer, Hoppe, Mohacsi, Schmitteckert, Gilsbach, Bünemann, Hein, Schwartz, Herzig: Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failure. in PLoS ONE 2007 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal CACNA2D1 Primary Antibody für IHC, IHC (p) - ABIN4286770 : Han, Du, Zhao, Li, Chen, Zhang, Liu, Suo, Bian, Xing, Zhang: PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells. in Nature communications 2015 (PubMed)

Weitere Antikörper gegen CACNA2D1 Interaktionspartner

Human Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Interaktionspartner

  1. we report an additional patient with the 7q21.11 deletion syndrome and provide evidence that haploinsufficiency for a single gene may not be the disease mechanism. In vitro studies of the interaction between PCLO (zeige PCLO Antikörper) and CACNA2D1 will be required to examine the hypothesis that combined haploinsufficiency for these two synaptic proteins results in neuronal dysfunction

  2. detected a joint effect of SNP and G x E interaction in BMP2 (zeige BMP2 Antikörper) and CACNA2D1 for depressive state.

  3. All three patients present with epilepsy and intellectual disability pinpointing the CACNA2D1 gene as an interesting candidate gene for these clinical features.

  4. Compound mutation of CACNA2D1 and RANGRF (zeige RANGRF Antikörper) genes were found. To the best of our knowledge, this is the first comprehensive description of the concurrence of these two mutations and histiocytoid cardiomyopathy.

  5. High prevalence of CACNA2D1, SCN5A (zeige SCN5A Antikörper), and CACNB2 (zeige CACNB2 Antikörper) genetic variants in the Danish population previously associated with Brugada syndrome has been found in new exome data.

  6. Functional expression of CACNA2D1 is inhibited by prion protein (zeige PRNP Antikörper) expression with competition at glycosylphosphatidylinositol.

  7. this study reports the identification and characterization of the human alpha2delta-1 subunit gene promoter region and its regulation by specific transcription factor 1 (zeige HNF1A Antikörper).

  8. In neocortical slices from transgenic mice having a point mutation (i.e., R217A) of the alpha2delta-1 subunit of voltage-sensitive calcium channels, pregabalin does not affect potassium-evoked glutamate (zeige GRIN1 Antikörper) release, yet inhibits this release in wild-type mice.

  9. Results show that mutation of CACNA2D1 gene causes a new varant of SCTS (zeige ANO6 Antikörper).

  10. CACNA2D1 is a novel Brugada Syndrome susceptibility gene.

Rabbit Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Interaktionspartner

  1. data support a model in which small neutral hydrophobic residues facilitate the post-translational cleavage of the CaValpha2delta1 subunit at the predicted membrane interface and further suggest that preventing GPI (zeige GPI Antikörper) anchoring of CaValpha2delta1 averts its cell-surface expression

  2. these findings provide evidence for a new role of Homer1 (zeige HOMER1 Antikörper) supporting the regulation of Cav1.2 (zeige CACNA1C Antikörper) channels by STIM1 (zeige STIM1 Antikörper).

Pig (Porcine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Interaktionspartner

Cow (Bovine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Interaktionspartner

  1. The objective of the present study was to identify polymorphisms of the CACNA2D1 gene, and to analyze associations between these polymorphisms and mastitis in several cattle breeds.

  2. CACNA2D1 gene is one of the potential candidate genes influencing carcass and meat quality traits.

Mouse (Murine) Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1) Interaktionspartner

  1. Loss of the Ca(2 (zeige CA2 Antikörper)+) channel alpha2delta-1 subunit function increases the susceptibility for developing diabetes in a sex-dependent manner.

  2. Linkage mapping, transcript covariance and pharmacological testing suggest that genetic variation affecting Cacna2d1 may contribute to individual differences in von Frey filament response.

  3. a TSP4 (zeige THBS4 Antikörper)/Cavalpha2delta1-dependent pathway activated by TSP4 (zeige THBS4 Antikörper) or peripheral nerve injury promotes exaggerated presynaptic excitatory input and evoked sensory neuron hyperexcitability and excitatory synaptogenesis.

  4. CaV2.2 (zeige CACNA1B Antikörper) and alpha2delta-1 are intimately associated at the plasma membrane

  5. These findings suggest that the alpha(2)delta(4) subunit participates in the modulation of L-type Ca(2 (zeige CA2 Antikörper)+) current regulating neurotransmitter release from photoreceptor terminals

  6. Expression of Cacna2d1 is enhanced in the amygdala in a model of innate anxiety.

  7. This study demonistrated that Cacna2d1 gene expression in mouse dorsal raphe nucleus

  8. association of calcium channel alpha2/delta subunit 1 and ATP5b (zeige ATP5B Antikörper) occurs in intracellular membranes and at the plasma membrane of developing muscle cells, where they form a signaling complex capable of accelerating the rate of decline of calcium transients

  9. mechanism of Cavalpha2delta1-mediated spinal sensitization in which elevated Cavalpha2delta1 causes increased pre-synaptic glutamate (zeige GRIN1 Antikörper) release that leads to reduced excitation thresholds of post-synaptic dorsal horn neurons to innocuous stimuli.

CACNA2D1 Antigen-Profil

Protein Überblick

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Genbezeichner und Symbole assoziert mit CACNA2D1

  • calcium voltage-gated channel auxiliary subunit alpha2delta 1 (CACNA2D1) Antikörper
  • calcium channel, voltage-dependent, alpha 2/delta subunit 1 (cacna2d1) Antikörper
  • calcium voltage-gated channel auxiliary subunit alpha2delta 1 (cacna2d1) Antikörper
  • calcium voltage-gated channel auxiliary subunit alpha2delta 1 (Cacna2d1) Antikörper
  • calcium channel, voltage-dependent, alpha2/delta subunit 1 (Cacna2d1) Antikörper
  • Ca(v)alpha2delta1 Antikörper
  • Cacna2 Antikörper
  • CACNA2D1 Antikörper
  • CACNL2A Antikörper
  • Cchl2a Antikörper
  • CCHLA2 Antikörper
  • DHSCCA Antikörper
  • DKFZp469K2211 Antikörper

Bezeichner auf Proteinebene für CACNA2D1

calcium channel, voltage-dependent, alpha 2/delta subunit 1 , voltage-dependent calcium channel subunit alpha-2/delta-1-like , calcium channel, L type, alpha 2 polypeptide , dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit , voltage-dependent calcium channel subunit alpha-2/delta-1 , voltage-gated calcium channel subunit alpha-2/delta-1 , dihydropryridine-sensitive calcium channel alpha-2 subunit , dihydropyridine-sensitive calcium channel alpha 2 , Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type)

GENE ID SPEZIES
463504 Pan troglodytes
708215 Macaca mulatta
100012746 Monodelphis domestica
100036724 Xenopus (Silurana) tropicalis
100171724 Pongo abelii
100463812 Ailuropoda melanoleuca
100566428 Anolis carolinensis
100595072 Nomascus leucogenys
781 Homo sapiens
100009105 Oryctolagus cuniculus
100728887 Cavia porcellus
768444 Gallus gallus
610342 Canis lupus familiaris
397377 Sus scrofa
282608 Bos taurus
12293 Mus musculus
25399 Rattus norvegicus
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