anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F) Antikörper

CACNA1F encodes a member of the alpha-1 subunit family\; a protein in the voltage-dependent calcium channel complex. Zusätzlich bieten wir Ihnen Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit Proteine (9) und Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CACNA1F 778 O60840
CACNA1F 114493  
CACNA1F 54652  
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Top anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit Antikörper auf antikoerper-online.de

Showing 10 out of 31 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded rat muscle tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CACNA1F Polyclonal Antibody, Unconjugated  at 1:300 overnight at 4°C, followed by a conjugated secondary and DAB staining Paraformaldehyde-fixed, paraffin embedded rat muscle tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CACNA1F Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a biotin conjugated secondary for 20 minutes and Cy3 streptavidin at 1:500 for 40 minutes and DAPI staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$417.45
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: Cav1.4 Antibody  - Immunohistochemical staining of human retina shows strong cytoplasmic positivity in photoreceptor cell segments. 100 μL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$417.45
Details
Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$417.45
Details
Human Kaninchen FITC IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$417.45
Details

Am meisten referenzierte anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit Antikörper

  1. Human Polyclonal CACNA1F Primary Antibody für IF (p) - ABIN1390134 : Haumann, Junghans, Anstötz, Frotscher: Presynaptic localization of GluK5 in rod photoreceptors suggests a novel function of high affinity glutamate receptors in the mammalian retina. in PLoS ONE 2017 (PubMed)

  2. Human Polyclonal CACNA1F Primary Antibody für ELISA, WB - ABIN560136 : Mizutani, Yamamura, Muramatsu, Kiyota, Nishimura, Suzuki, Ohya, Imaizumi: Spontaneous and nicotine-induced Ca2+ oscillations mediated by Ca2+ influx in rat pinealocytes. in American journal of physiology. Cell physiology 2014 (PubMed)

Weitere Antikörper gegen Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit Interaktionspartner

Human Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F) Interaktionspartner

  1. CaV1.4 channels are indeed modulated by PKA phosphorylation within the inhibitor of Ca(2 (zeige CA2 Antikörper)+)-dependent inactivation (ICDI) motif.

  2. AED, iCSNB, and X-linked cone-rod dystrophy 3 are designations that refer to a broad, continuous spectrum of clinical appearances caused in the majority by a variety of mutations in CACNA1F.

  3. exon 47 encodes structural determinants that regulate CDI and voltage-dependent activation of Cav1.4, and is necessary for modulation of channel activation by CaBP4 (zeige CABP4 Antikörper).

  4. Studies indicate a role for L-type calcium channel Cav1.3 and Cav1.4 in cochlear inner hair cells (IHCs) and retinal photoreceptors (PRs).

  5. a single nucleotide change c.1555C>T in exon 13 of the CACNA1F gene, leading to the substitution of arginine by tryptophan (p.R519W) in a Chinese individual affected by retinitis pigmentosa, is identified.

  6. novel heterozygous missense mutation (c.1555C>T, p.R519W) in CACNA1F gene, which is probably associated with XLRP.

  7. analysis of Cav1.4 complexes alpha11.4, beta2, and alpha2delta4 in HEK293T cells and in mouse retina

  8. Data on Cav1.4 deficient mice and human female carriers of mutations in CACNA1F are consistent with a phenotype of mosaic congenital stationary night blindness type 2A.

  9. Mutation in Cav1.4 gene is associated with congenital stationary night blindness type 2.

  10. Our data independently confirm CACNA1F as the causative gene for CORDX3-like phenotypes and detailed clinical characterization of the family expands the knowledge about the phenotypic spectrum of deleterious CACNA1F alterations.

Zebrafish Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F) Interaktionspartner

  1. CACNA1F exhibited small spot-like staining beneath the RIM2 (zeige RIMS2 Antikörper) and RIBEYE (zeige CTBP2 Antikörper) structures.

Mouse (Murine) Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F) Interaktionspartner

  1. Results show that genetic deletion of the synaptic Cav1.4 L-type voltage-gated calcium channels impairs calpain activation and leads to a short-term preservation of photoreceptors in the rd1 (zeige PDE6B Antikörper) mouse.

  2. analysis of Cav1.4 complexes alpha11.4, beta2, and alpha2delta4 in HEK293T cells and in mouse retina

  3. CaBP4 (zeige CABP4 Antikörper) forms a collapsed structure around the IQ motif in Cav1.4 that may promote channel activation by disrupting an interaction between IQ and the inhibitor of Ca(2 (zeige CA2 Antikörper)+)-dependent inactivation domain

  4. the importance of proper Cav (zeige CA5A Antikörper) 1.4 function for efficient PR synapse maturation, and that dysregulation of Cav (zeige CA5A Antikörper) 1.4 channels in CSNB2 may have synaptopathic consequences

  5. model for vision impairment with Cav1.4 mutation

  6. Data on Cav1.4 deficient mice and human female carriers of mutations in CACNA1F are consistent with a phenotype of mosaic congenital stationary night blindness type 2A.

  7. In the absence of the CaV1.4 channel, photoreceptor synapses remain immature and are unable to stabilize.

  8. Complex regulation of voltage-dependent activation and inactivation properties of retinal voltage-gated Cav1.4 L-type Ca2 (zeige CA2 Antikörper)+ channels by Ca2 (zeige CA2 Antikörper)+-binding protein 4 (CaBP4 (zeige CABP4 Antikörper)).

  9. Proper targeting of synaptic proteins and PMCAs to photoreceptor terminals requires adequate expression of Cav1.4 subunit.

  10. Cacna1f ( G305X ) is a true knockout model for human congenital stationary night blindness 2 (CSNB2), with prominent defects in cone and rod function. Cacna1f ( nob2 ) is an incomplete knockout model for CSNB2.

Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F) Antigen-Profil

Protein Überblick

This gene encodes a member of the alpha-1 subunit family\; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2).

Genbezeichner und Symbole assoziert mit CACNA1F

  • calcium voltage-gated channel subunit alpha1 F (CACNA1F) Antikörper
  • calcium voltage-gated channel subunit alpha1 F (Cacna1f) Antikörper
  • voltage-dependent L-type calcium channel subunit alpha-1F (LOC465629) Antikörper
  • calcium channel, voltage-dependent, L type, alpha 1F subunit (cacna1fb) Antikörper
  • calcium channel, voltage-dependent, L type, alpha 1F subunit a (cacna1fa) Antikörper
  • calcium voltage-gated channel subunit alpha1 F (cacna1f) Antikörper
  • calcium channel, voltage-dependent, alpha 1F subunit (Cacna1f) Antikörper
  • A930034B14 Antikörper
  • AIED Antikörper
  • CACNA1F Antikörper
  • Cav1.4 Antikörper
  • Cav1.4alpha1 Antikörper
  • COD3 Antikörper
  • COD4 Antikörper
  • CORDX Antikörper
  • CORDX3 Antikörper
  • CSNB2 Antikörper
  • CSNB2A Antikörper
  • CSNBX2 Antikörper
  • JM8 Antikörper
  • JMC8 Antikörper
  • nerg1 Antikörper
  • nob2 Antikörper
  • OA2 Antikörper
  • Sfc17 Antikörper

Bezeichner auf Proteinebene für CACNA1F

voltage-dependent L-type calcium channel subunit alpha-1F , voltage-gated calcium channel subunit alpha Cav1.4 , calcium channel, voltage-dependent, alpha 1F subunit , calcium channel, voltage-dependent, L type, alpha 1F subunit , voltage-dependent L-type calcium channel subunit alpha-1F-like , L-type dihydropyridine-sensitive calcium channel alpha-1f subunit , LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1F

GENE ID SPEZIES
778 Homo sapiens
114493 Rattus norvegicus
465629 Pan troglodytes
480915 Canis lupus familiaris
509779 Bos taurus
559964 Danio rerio
715787 Macaca mulatta
793708 Danio rerio
100386041 Callithrix jacchus
100565753 Anolis carolinensis
54652 Mus musculus
100514745 Sus scrofa
Ausgewählte Anbieter für anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1F Subunit (CACNA1F) Antikörper
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