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CRTC3 is a member of the CREB regulated transcription coactivator gene family. Zusätzlich bieten wir Ihnen CRTC3 Kits (5) und CRTC3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal CRTC3 Primary Antibody für ICC, IHC - ABIN969068
Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: A new type of MAML2 fusion in mucoepidermoid carcinoma. in Genes, chromosomes & cancer 2008
Show all 2 Pubmed References
the existence of an unusual functional interplay between STATs and CREB (zeige CREB1 Antikörper) at the onset of adipogenesis through shared CRTC cofactors, is reported.
Three mouse CRTCs (Crtc1 (zeige CRTC1 Antikörper), Crtc2 (zeige CRTC2 Antikörper) and Crtc3) exhibit distinct patterns of 14-3-3 (zeige YWHAQ Antikörper) binding at three conserved sites corresponding to S70, S171 (zeige NUMB Antikörper), and S275 (in CRTC2 (zeige CRTC2 Antikörper)).
beta-agonists or catecholamines released during intense exercise induce Creb (zeige CREB1 Antikörper)-mediated transcriptional programs through activation of its obligate coactivators Crtc2 (zeige CRTC2 Antikörper) and Crtc3.
CRTC3 plays a selective role in mitochondrial biogenesis in response to rotenone
the cAMP response element binding (CREB) coactivator Crtc3 promotes obesity by attenuating beta-adrenergic receptor signalling in adipose tissue
revealing neither correlation between the cellular composition and CRTC1 (zeige CRTC1 Antikörper)-MAML2 (zeige MAML2 Antikörper) fusions nor presence of CRTC3-MAML2 (zeige MAML2 Antikörper) fusions in cutaneous hidradenoma
The CRTC3 polymorphism rs3862434 is associated with the plasma level of total cholesterol, and rs11635252 is associated with the risks of overweight and hypertriglyceridemia in a Chinese Han population.
Metaplastic Warthin tumor and metaplastic pleomorphic adenoma of salivary glands did not harbor CRTC1 (zeige CRTC1 Antikörper)-MAML2 (zeige MAML2 Antikörper) and CRTC3-MAML2 (zeige MAML2 Antikörper) fusion transcripts, respectively, or MAML2 (zeige MAML2 Antikörper) gene rearrangement.
mucoepidermoid carcinoma of the salivary glands positive for CRTC1 (zeige CRTC1 Antikörper)-MAML2 (zeige MAML2 Antikörper) or CRTC3-MAML2 (zeige MAML2 Antikörper) fusion formed a favourable tumour subset that was distinct from fusion-negative cases
As a common human CRTC3 variant with increased transcriptional activity is associated with adiposity in two distinct Mexican-American cohorts, results suggest that adipocyte CRTC3 may play a role in the development of obesity in humans
Mucoepidermoid carcinomas possessing CRTC3-MAML2 (zeige MAML2 Antikörper) fusion may be associated with favorable clinicopathological features and patients may be younger than those with CRTC1 (zeige CRTC1 Antikörper)-MAML2 (zeige MAML2 Antikörper) fusion or those with no detectable gene fusion.
transducer of regulated cyclic AMP-response element-binding protein 3 (zeige HSPB3 Antikörper) (TORC3), a co-activator of CREB (zeige CREB1 Antikörper), is involved in Tax (zeige CNTN2 Antikörper)-induced transcriptional activation from the HTLV-I LTR
These results strongly suggest that TORCs play a key role in linking these external signals to the transcriptional program of adaptive mitochondrial biogenesis by activating PGC-1alpha gene transcription.
BCL3 (zeige BCL3 Antikörper) functions as a repressor of HTLV-1 LTR-mediated transcription through interactions with TORC3
This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
transducer of regulated CREB protein 3
, CREB regulated transcription coactivator 3
, CREB-regulated transcription coactivator 3
, transducer of CREB protein 3
, transducer of regulated cAMP response element-binding protein 3
, CREB-regulated transcription coactivator 3-like
, transducer of regulated cAMP response element-binding protein (CREB) 3