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CMTM7 belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. Zusätzlich bieten wir Ihnen CMTM7 Kits (20) und CMTM7 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Findings indicate the role of CMTM7 protein in the regulation of epidermal growth factor receptor (EGFR (zeige EGFR Antikörper))-AKT (zeige AKT1 Antikörper) proto-oncogene (zeige RAB1A Antikörper) protein signaling in tumor cells, and as a molecule related to Rab5 (zeige RAB5A Antikörper) GTP-binding protein (zeige HCAR3 Antikörper) activation.
Loss of CMTM7 by promoter CpG methylation is associated with neoplasms.
The CMTM7 expression may be related to survival of patients with non-smallcell lung cancer and a unique prognostic factor. CMTM7 may play an important role in NSCLC development.
CMTM7 functions to link sIgM and BLNK (zeige BLNK Antikörper) in the plasma membrane.
Bioinformatics based on CKLF2 (zeige CKLF Antikörper) cDNA and protein sequences in combination with experimental validation identified CKLFSF1 (zeige CMTM1 Antikörper)-8 gene clusters, between the SCY (zeige CELSR1 Antikörper) and the TM4SF (zeige TSPAN1 Antikörper) gene families. The 8 family members were cloned and characterized.
The reduction of B-1a cells in Cmtm7(flox/) mice was associated with reduced BCR (zeige BCR Antikörper) expression.
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified.
CKLF-like MARVEL transmembrane domain-containing protein 7
, chemokine-like factor super family 7
, chemokine-like factor super family member 7 variant 2
, chemokine-like factor superfamily 7
, chemokine-like factor superfamily member 7
, CKLF-like MARVEL transmembrane domain containing 7 L homeolog