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CDK5 Regulatory Subunit Associated Protein 3 Proteine (CDK5RAP3)

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. Zusätzlich bieten wir Ihnen CDK5 Regulatory Subunit Associated Protein 3 Antikörper (62) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CDK5RAP3 80279 Q96JB5
CDK5RAP3 80280 Q99LM2
CDK5RAP3 80278 Q9JLH7
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Top CDK5 Regulatory Subunit Associated Protein 3 Proteine auf antikoerper-online.de

Showing 7 out of 7 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$492.31
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,430.17
Details
Escherichia coli (E. coli) Human His tag   100 μL Anmelden zum Anzeigen 9 bis 11 Tage
$423.21
Details

CDK5RAP3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) Interaktionspartnern

Human CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) Interaktionspartner

  1. Our results demonstrated that CDK5RAP3 negatively regulates the Wnt/beta-catenin signaling pathway by repressing AKT phosphorylation, which leads to better survival of patients with gastric cancer.

  2. Prognostic analysis showed that the co-expression of CDK5RAP3 and DDRGK1 was an independent prognostic factor correlating with the overall survival of gastric cancer patients.

  3. CDK5RAP3 negatively regulates the beta-catenin signaling pathway by repressing GSK-3beta phosphorylation in gastric neoplasms.

  4. C53/LZAP protein bound indirectly to the microtubule (MT), and expression of the C53/LZAP cleavage product caused abnormal MT bundling and NE rupture.

  5. our findings provide the new evidence that overexpression of CDK5RAP3 promotes HCC metastasis via downregulation of p14(ARF).

  6. LZAP may play an important role in hepatocellular carcinoma progression

  7. our results strongly suggest that the binding of hepatitis viral pre-S2 LHBs with C53 is a novel negative regulator of the checkpoint response

  8. Data indicate that IC53 is a positive mediator for colon cancer progression, and IC53-rs2737 may serve as protection from the onset of colorectal cancer.

  9. Nuclear gamma-tubulin interacts with tumor suppressor protein C53 that is involved in regulation of DNA damage

  10. the ability of LZAP to alter p38 phosphorylation depended, at least partially, on the p38 phosphatase, Wip1

  11. Findings reveal that CDK5RAP3 is widely overexpressed in hepatocellular carcinoma and that overexpression of CDK5RAP3 promotes HCC metastasis through PAK4 activation.

  12. found that C53/LZAP and DDRGK1 became more susceptible to the proteasome-mediated degradation in RCAD knockdown cells, whereas their ubiquitination was significantly attenuated by RCAD overexpression

  13. IC53 is a novel gene, mainly expressed in vascular endothelial cells and mediates cell proliferation

  14. results strongly indicate that in response to genotoxic stress, Cdk5 activator-binding protein C53(C53) serves as an important regulatory component of DNA damage checkpoint through modulating cyclin dependent kinase 1-cyclin B1 function

  15. It is suggested that LZAP can regulate ARF biochemical and biological activity; additionally, LZAP has p53-dependent cell-cycle effects that are independent of ARF.

  16. it is concluded that CDK5RAP3, CCNB2, and RAGE genes may be used as a very reliable biomarkers of lung adenocarcinoma

  17. LZAP has a role in NF-kappaB regulation and tumor suppression.

  18. CDK5 regulatory subunit associated protein 3 promotes checkpoint kinase 1 activation and mitotic entry in both unperturbed cell-cycle progression and DNA damage response.

  19. Endothelium-specific overexpression of human IC53 downregulates endothelial nitric oxide synthase activity and elevates systolic blood pressure in mice.

Mouse (Murine) CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) Interaktionspartner

  1. Results suggest that C53 might play a role in regulating neuronal proliferation, migration and/or differentiation in embryonic development.

CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3) Protein Überblick

Protein Überblick

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.

Genbezeichner und Symbole assoziert mit CDK5RAP3

  • CDK5 regulatory subunit associated protein 3 (cdk5rap3)
  • CDK5 regulatory subunit associated protein 3 (CDK5RAP3)
  • CDK5 regulatory subunit associated protein 3 L homeolog (cdk5rap3.L)
  • CDK5 regulatory subunit associated protein 3 (Cdk5rap3)
  • 1810007E24Rik Protein
  • BC002318 Protein
  • C53 Protein
  • C81486 Protein
  • cdk5rap3 Protein
  • cdkrap3 Protein
  • fb33h04 Protein
  • fc09c05 Protein
  • HSF-27 Protein
  • IC53 Protein
  • id:ibd2920 Protein
  • LZAP Protein
  • MGC82350 Protein
  • MST016 Protein
  • OK/SW-cl.114 Protein
  • PP1553 Protein
  • wu:fb33h04 Protein
  • wu:fc09c05 Protein
  • zgc:86863 Protein

Bezeichner auf Proteinebene für CDK5RAP3

CDK5 regulatory subunit-associated protein 3 , lzap , CDK5 regulatory subunit associated protein 3 , CDK5 regulatory subunit-associated protein 3-like , CDK5 regulatory subunit associated protein IC53-2 , LXXLL/leucine-zipper-containing ARFbinding protein , ischemic heart CDK5 activator-binding protein C53 , OK/SW-cl.114 , CDK5 activator-binding protein C53 , CDK5 activator-binding protein C53

GENE ID SPEZIES
415195 Danio rerio
430350 Gallus gallus
455182 Pan troglodytes
496928 Xenopus (Silurana) tropicalis
735047 Xenopus laevis
100481577 Ailuropoda melanoleuca
695189 Macaca mulatta
80279 Homo sapiens
80280 Mus musculus
80278 Rattus norvegicus
480541 Canis lupus familiaris
509255 Bos taurus
100174141 Pongo abelii
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