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The protein encoded by CLK4 belongs to the CDC2-like protein kinase (CLK) family. Zusätzlich bieten wir Ihnen CLK4 Antikörper (41) und CLK4 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.
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Clk1, Clk2 and Clk4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint.
Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.
Clk1/4 expression induced by stress-responsive splicing serves to maintain the phosphorylation state of SR proteins.
The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
dual specificity protein kinase CLK4
, protein serine threonine kinase Clk4
, CDC-like kinase 4
, CDC-like kinase 4b