CCHC-Type Zinc Finger, Nucleic Acid Binding Protein Proteine (CNBP)

CNBP encodes a nucleic-acid binding protein with seven zinc-finger domains. Zusätzlich bieten wir Ihnen CNBP Antikörper (107) und CNBP Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CNBP 7555 P62633
CNBP 64530 P62634
CNBP 12785 P53996
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Top CNBP Proteine auf antikoerper-online.de

Showing 8 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Anmelden zum Anzeigen 11 Days
$411.40
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,388.83
Details
Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,398.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,410.83
Details

CNBP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Rat (Rattus)

Mouse (Murine)

Am meisten referenzierte CNBP Proteine

  1. Human CNBP Protein expressed in Wheat germ - ABIN1349806 : Raheem, Olufemi, Bachinski, Vihola, Sirito, Holmlund-Hampf, Haapasalo, Li, Udd, Krahe: Mutant (CCTG)n expansion causes abnormal expression of zinc finger protein 9 (ZNF9) in myotonic dystrophy type 2. in The American journal of pathology 2010 (PubMed)

Weitere Proteine zu CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) Interaktionspartnern

Human CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) Interaktionspartner

  1. The authors report a previously unknown long noncoding RNA which, together with CNBP, is involved in the fine-tuned regulation of CCND1 mRNA stability, without which CCND1 exhibits, at most, partial expression.

  2. [CCTG]n repeat expansion, differently from the DM1 mutation, does not influence the methylation status of the CNBP gene and other molecular mechanisms are involved in the pathogenesis of Myotonic Dystrophy type 2..

  3. RNA sequence preferences of unconventional RNA-binding proteins, Nudt21 and CNBP, has been described.

  4. A second point is that DM mutations, although located in noncoding regions, may reduce the expression of mutant alleles, raising questions whether loss-of-function may contribute to the phenotype, or possibly impose a safety limit on knockdown therapies that create or aggravate a DMPK or CNBP deficiency state

  5. CNBP is supporting translation by resolving stable structures on mRNAs.

  6. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage.

  7. The cnbp overexpression rescued the Treacher Collins Syndrome phenotype in a dose-dependent manner by a reactive oxygen species-cytoprotective action that prevented the redox-responsive genes' upregulation but did not normalize the synthesis of ribosomal RNAs.

  8. High CNBP expression is associated with Medulloblastoma.

  9. CNBP overexpression caused increase of cell death and suppression of cell metastasis through its induction of G-quadruplex formation in the promoter of hnRNP K resulting in hnRNP K down-regulation

  10. Arginine methylation of CNBP in the RG motif does not change the subcellular localization but regulates its RNA binding activity.

  11. CNBP are novel antigens for SLE patients and the recognition of CNBP might be differentiated dependent on the level of arginine methylation.

  12. suggested a new possibility of CNBP as a potential anti-cancer target based on CNBP's biological function in c-myc transcription

  13. CNBP associates with the poly(A) binding protein and accumulates in stress granules.

  14. The co-segregation of Myotonic dystrophy type 2 with a recessive CLCN1 mutation provided the explanation for the unusual clinical findings for juvenile onset of myotonia in a 14-year-old female with Myotonic dystrophy type 2 and her affected mother

  15. Myotonic dystrophy 2(autosomal dominant, multisystem disorder caused by a CCTG tetranucleotide repeat expansion located in intron 1 of the zinc finger protein 9 gene (ZNF9 gene) on chromosome 3q 21.3.) described in Israeli Jewish European ancestry.

  16. CCTG repeat expansions in the CNBP gene are responsible for myotonic dystrophy type 2.

  17. Study concludes that DM2 patients from the Netherlands, including a North-African family, harbor a common haplotype surrounding the ZNF9 gene.

  18. These data suggest that Gis2 is functionally orthologous to ZNF9 and acts as a cap-independent translation factor.

  19. ZNF9 expression in myotonic dystrophy type 2 patients is altered at multiple levels.

  20. ZNF9 is abundantly expressed in human myofibres, where it is located in the sarcomeric I bands, and no modification of this pattern is observed in myotonic dystrophy type 2 muscles.

Mouse (Murine) CCHC-Type Zinc Finger, Nucleic Acid Binding Protein (CNBP) Interaktionspartner

  1. our study suggests that CNBP could maintain testicular development by inhibiting the Wnt/beta-catenin pathway, particularly by influencing Sertoli cells.

  2. A G-rich motif in the lncRNA Braveheart interacts with Cnbp to specify the cardiovascular lineage.

  3. data support a role for CNBP as a critical transcription factor and a key regulator of the prolonged expression of sustained cytokine IL-6 during persistent LPS stimulation or Gram-negative bacterial infection

  4. CNBP up-regulates tbx2b and smarca5, and down-regulates wnt5b gene expression.

  5. expression of APP(Swe) in murine tissue induces a decrease in CNBP expression.

  6. CNBP targets Myc in rostral head formation, is essential for forebrain induction and specification.

CNBP Protein Überblick

Protein Überblick

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CNBP

  • cellular nucleic acid-binding protein (ANI_1_1316064)
  • cellular nucleic acid-binding protein (AOR_1_1792194)
  • cellular nucleic acid-binding protein (PTRG_02341)
  • cellular nucleic acid-binding protein (PTRG_04792)
  • zinc finger protein Byr3 (SJAG_02043)
  • cellular nucleic acid-binding protein (VDBG_00279)
  • cellular nucleic acid-binding protein (VDBG_00590)
  • CCHC-type zinc finger nucleic acid binding protein (CNBP)
  • CCHC-type zinc finger, nucleic acid binding protein (Cnbp)
  • CCHC-type zinc finger nucleic acid binding protein L homeolog (cnbp.L)
  • cellular nucleic acid binding protein (Cnbp)
  • AA408710 Protein
  • An07g10270 Protein
  • cnbp1 Protein
  • cnbpa Protein
  • dm2 Protein
  • promm Protein
  • rnf163 Protein
  • xcnbp Protein
  • zcchc22 Protein
  • znf9 Protein

Bezeichner auf Proteinebene für CNBP

cellular nucleic acid-binding protein , zinc finger protein 9 , cellular nucleic acid binding protein , erythroid differentiation-related , sterol regulatory element-binding protein , zinc finger protein 273 , zinc finger protein 9 (a cellular retroviral nucleic acid binding protein) , cellular nucleic acid binding protein 1 , cellular nucleic acid binding protein a , DNA binding protein

GENE ID SPEZIES
4982296 Aspergillus niger CBS 513.88
5988418 Aspergillus oryzae RIB40
6340586 Pyrenophora tritici-repentis Pt-1C-BFP
6343034 Pyrenophora tritici-repentis Pt-1C-BFP
7047891 Schizosaccharomyces japonicus yFS275
9528787 Verticillium alfalfae VaMs.102
9534044 Verticillium alfalfae VaMs.102
100173703 Pongo abelii
7555 Homo sapiens
64530 Rattus norvegicus
476518 Canis lupus familiaris
399294 Xenopus laevis
504831 Bos taurus
395731 Gallus gallus
12785 Mus musculus
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