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The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. Zusätzlich bieten wir Ihnen CEBPD Antikörper (63) und CEBPD Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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we found that ROS formation and expression of p47(phox) and p67(phox), subunits of NADPH oxidase, were increased in AppTg mice but attenuated in AppTg/Cebpd(-/-) mice. Cebpd can up-regulate p47(phox) and p67(phox) transcription via a direct binding on their promoters, which results in an increase in intracellular oxidative stress
tudy underscores how CEBPD functions at the junction of inflammation and lipid accumulation in M1 macrophages
astrocytic C/EBPdelta is integral to the inflammatory cascades leading to glial scar formation after spinal cord injury.
These findings demonstrate a critical function for the astrocytic CEBPD, and point to miR-135a antagonist as an attractive therapeutic target for the treatment of Alzheimer's disease.
This study demonstrates a novel role for CEBPd in protection from basal as well as radiation-induced oxidative stress and mitochondrial dysfunction thus promoting post-radiation survival.
Results show that C/EBPbeta (zeige CEBPB ELISA Kits) and C/EBPdelta actively regulate the promotor region of both splicing variants Ppargamma1sv and Ppargamma2 (zeige PPARG ELISA Kits) in mouse adipocytes.
C/EBPdelta facilitates bacterial dissemination to the brain and enhances the immune response in the blood compartment. This study suggests that C/EBPdelta plays a detrimental role during the initial development of blood-borne brain infection.
Taken together, these results suggested that alpha1B-adrenoceptor signaling is required for bone formation and regulated cellular proliferation through a mechanism relevant to the up-regulation of CCAAT/enhancer-binding protein delta in osteoblasts and, thus, provide new evidence for the physiological importance of alpha1B-adrenoceptor signalling in bone homeostasis
The C/EBPdelta in the brain drives the inflammatory response and contributes to bacterial dissemination during pneumococcal meningitis. C/EBPdelta does, however, not affect clinical parameters of the disease and does not confer a survival benefit.
CEBPA (zeige CEBPA ELISA Kits), CEBPB (zeige CEBPB ELISA Kits) and CEBPD regulate proliferation and differentiation of chondrocytes.
the EGFR (zeige EGFR ELISA Kits)/STAT3 (zeige STAT3 ELISA Kits) pathway contributed to CDDP-induced CEBPD expression in UCUB cells. Gefitinib and S3I-201 treatment significantly reduced the expression of CEBPD and enhanced the sensitivity of CDDP-resistant UCUB cells to CDDP and paclitaxel
These findings identify a molecular mechanism by which ERalpha (zeige ESR1 ELISA Kits) signaling reduces the aggressiveness of cancer cells, and demonstrate that C/EBPdelta can have different functions in different types of cancer.
CREB (zeige CREB1 ELISA Kits) overexpression increased CCAAT-enhancer-binding protein-delta (C/EBPdelta) levels to cause myeloid differentiation arrest, and the silencing of CREB (zeige CREB1 ELISA Kits)-C/EBPdelta axis restored myeloid terminal differentiation
Data suggest that proinflammatory cytokine interleukin-1beta (IL1B (zeige IL1B ELISA Kits)) up-regulates hepcidin (zeige HAMP ELISA Kits) expression in hepatocytes; inflammation induces IL1B (zeige IL1B ELISA Kits) production in Kupffer cells and hepatocytes; IL1B (zeige IL1B ELISA Kits) up-regulates CEBPD (CCAAT/enhancer binding protein delta) expression in hepatocytes; up-regulation of CEBPD expression up-regulates hepcidin (zeige HAMP ELISA Kits) transcription.
the C/EBPD binding site is required for RU486-mediated activation of the CHOP (zeige DDIT3 ELISA Kits) promoter.
Results suggest that CCAAT/enhancer binding protein delta (CEBPD) could be a useful diagnostic marker and therapeutic target in hepatocellular carcinoma (HCC).
CEBPD amplification and overexpression is associated with urothelial carcinoma.
Knock-down of C/EBPdelta expression in pericytes following immune stimulation increased chemokine (zeige CCL1 ELISA Kits) and adhesion molecule (zeige NCAM1 ELISA Kits) expression.
Elevated C/EBPdelta can induce the adipogenesis in the fibroblasts of cattle.
Xenopus C/EBP delta plays a role in apoptotic cell death of larval-type epithelium during the stomach remodeling.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11.
CCAAT/enhancer-binding protein delta
, c/EBP delta
, c/EBP-related protein 3
, nuclear factor NF-IL6-beta
, transcription factor CELF
, CCAAT/enhancer binding protein delta
, binding protein (C/EBP), delta
, CCAAT-enhancer binding protein delta
, X. C/EBP delta-2
, X. C/EBP delta-1
, C/EBP delta
, cebpd, CCAAT/enhancer binding protein (C/EBP), delta
, CCAAT/enhancer binding protein (C/EBP), delta