anti-C-Type Lectin Domain Family 6, Member A (CLEC6A) Antikörper

Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 6, Member A Proteine (10) und C-Type Lectin Domain Family 6, Member A Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CLEC6A 56620 Q9JKF4
CLEC6A 93978 Q6EIG7
CLEC6A    
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Top anti-C-Type Lectin Domain Family 6, Member A Antikörper auf antikoerper-online.de

Showing 10 out of 159 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CLEC6A Antibody Titration:  0.2-1 ug/ml  Positive Control:  THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
€251.30
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Dectin 2 expression in SHSY5Y (A), NS-1 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
€423.91
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of Dectin-2/CLEC6A in Human Monocytes by Flow Cytometry. Human blood-derived monocytes were stained with Mouse Anti-Human Dectin-2/CLEC6A Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
€265.00
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
€479.85
Details
Human Maus APC FACS Detection of Dectin-2/CLEC6A in Human PBMC Monocytes by Flow Cytometry. Human peripheral blood mononuclear cell (PBMC) monocytes were stained with (A) Mouse Anti-Human CD14 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
€362.00
Details
Human Maus Unkonjugiert FACS, IHC, IHC (p), WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
€441.59
Details
Human Kaninchen Unkonjugiert WB CLEC6A Antibody (C-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the CLEC6A antibody detected the CLEC6A protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
€291.74
Details
Human Maus Fluorescein FACS Detection of Dectin-2/CLEC6A in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Dectin-2/CLEC6A Fluorescein-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
€260.00
Details
Human Maus PE FACS Detection of Dectin-2/CLEC6A in Human Blood Monocytes by Flow Cytometry. Human peripheral blood monocytes were stained with Mouse Anti-Human Dectin-2/CLEC6A PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
€311.00
Details
Human Maus Alexa Fluor 700 FACS Detection of Dectin-2/CLEC6A in Human PBMCs Monocytes by Flow Cytometry. Human peripheral blood mononuclear cell (PBMC) monocytes were stained with Mouse Anti-Human Dectin-2/CLEC6A Alexa Fluor 700-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
€332.00
Details

CLEC6A Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-C-Type Lectin Domain Family 6, Member A Antikörper

  1. Human Polyclonal CLEC6A Primary Antibody für IHC (fro), IHC (p) - ABIN315995 : Brasch, Mörig, Neumann, Proksch: Expression of antimicrobial peptides and toll-like receptors is increased in tinea and pityriasis versicolor. in Mycoses 2014 (PubMed)

  2. Human Monoclonal CLEC6A Primary Antibody für FACS - ABIN4897579 : Botting, Bertram, Baharlou, Sandgren, Fletcher, Rhodes, Rana, Plasto, Wang, Lim, Barnouti, Kohout, Papadopoulos, Merten, Olbourne, Cunningham, Haniffa, Harman: Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes. in Journal of leukocyte biology 2017 (PubMed)

  3. Human Monoclonal CLEC6A Primary Antibody für CyTOF, FACS - ABIN4900356 : Gringhuis, Wevers, Kaptein, van Capel, Theelen, Boekhout, de Jong, Geijtenbeek: Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2. in PLoS pathogens 2011 (PubMed)

Weitere Antikörper gegen C-Type Lectin Domain Family 6, Member A Interaktionspartner

Mouse (Murine) C-Type Lectin Domain Family 6, Member A (CLEC6A) Interaktionspartner

  1. Dectin-2 is a primary factor in activation of NLRP3 (zeige NLRP3 Antikörper) inflammasome during Histoplasma capsulatum infection.

  2. this report relates the potential of the Dectin-2/Card9 (zeige CARD9 Antikörper)-coupled pathway in ocular autoimmunity. Not only does it contribute to understanding of how innate immune receptors orchestrate T cell-mediated autoimmunity, it also reveals a previously unappreciated ability of fungal-derived signals to promote autoimmunity.

  3. a glycosylated protein with mannose-related structure is recognized by Dectin-2 in dendritic cells

  4. Dectin-2 does not play a major role in in phagocytosis and innate defense by phagocytes against Cryptococcus neoformans spores.

  5. activation of CLRs Dectin-2 and Dectin-3 by fungi infections triggers them for ubiquitination and degradation in a Syk (zeige SYK Antikörper)-dependent manner.

  6. this study shows that in vitro, cytokine production by bone marrow-derived dendritic cells is dependent on dectin-2; in vivo, its deficiency compromises fungal clearance

  7. these data indicate that mannosylated O-antigens from several Gram-negative bacteria augment TLR4 (zeige TLR4 Antikörper) responses through interaction with Dectin-2.

  8. Dectin-2 leads to an increase in cardiac rupture, impairs wound healing, and aggravates cardiac remodeling after MI through the modulation of Th1 (zeige HAND1 Antikörper) differentiation.

  9. this study demonstrates the role of Dectin-2 as an essential trigger of host defense in a murine model of systemic candidiasis

  10. The results indicate differential roles for Dectin-2 and Mincle (zeige CLEC4E Antikörper) in the generation of adaptive immune responses to F. pedrosoi fungal infection in mice.

Human C-Type Lectin Domain Family 6, Member A (CLEC6A) Interaktionspartner

  1. Data suggest that the specificity and geometry of dectin-2/CLEC6A carbohydrate-binding site provide molecular mechanism for binding of dectin-2 to fungal mannans and also to bacterial lipopolysaccharides, capsular polysaccharides, and lipoarabinomannans that contain mannose-alpha-1--2-mannose disaccharide unit. (CLEC6A = C-type lectin (zeige MBL2 Antikörper) domain containing 6A)

  2. these data indicate that mannosylated O-antigens from several Gram-negative bacteria augment TLR4 (zeige TLR4 Antikörper) responses through interaction with Dectin-2.

  3. This study showed a genetic association between Dectin-2 and pulmonary cryptococcosis.

  4. human plasmacytoid dendritic cells directly recognize A. fumigatus hyphae via Dectin-2

  5. our data show a requirement for Dectin-2 in alveolar macrophage induction of cysteinyl leukotrienes and in the initiation of airway inflammation.

  6. The Dectin-2 possess a single extracellular conserved C-type lectin (zeige MBL2 Antikörper)-like domain and are capable of mediating intracellular signalling either directly, through integral signalling domains, or indirectly, by associating with signalling adaptor molecules.

  7. Thus, dectin-1 (zeige CLEC7A Antikörper) and dectin-2 control adaptive T(H)-17 immunity to fungi via Malt1 (zeige MALT1 Antikörper)-dependent activation of c-Rel (zeige NFkBP65 Antikörper).

  8. human DECTIN-2 has a role in innate immunity

C-Type Lectin Domain Family 6, Member A (CLEC6A) Antigen-Profil

Protein Überblick

Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functionnal receptor for alpha-mannans on C. albicans hypheas. Plays an important role in the host defense against C. albicans infection by inducing TH17 cell differentiation. Recognizes also, in a manose dependent manner, allergens from house dust mite and fungi, by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni altering adaptative immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and Syk-CARD9-NF-kappa-B-dependent pathway.

Genbezeichner und Symbole assoziert mit CLEC6A

  • C-type lectin domain containing 6A (CLEC6A) Antikörper
  • C-type lectin domain family 4, member n (Clec4n) Antikörper
  • CLEC4N Antikörper
  • Clec6a Antikörper
  • CLECSF10 Antikörper
  • Nkcl Antikörper

Bezeichner auf Proteinebene für CLEC6A

C-type lectin domain family 6, member A , C-type lectin domain family 6 member A , dectin-2 , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10 , C-type lectin superfamily member 10 , DC-associated C-type lectin 2 , dendritic cell-associated C-type lectin 2 , natural killer complex lectin , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 10 , dectin 2

GENE ID SPEZIES
678675 Ovis aries
735479 Pan troglodytes
56620 Mus musculus
93978 Homo sapiens
514979 Bos taurus
Ausgewählte Anbieter für anti-C-Type Lectin Domain Family 6, Member A (CLEC6A) Antikörper
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