C-Type Lectin Domain Family 1, Member B (CLEC1B) ELISA Kits

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1\; MIM 602894) and NKG2D (KLRC4\; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. Zusätzlich bieten wir Ihnen C-Type Lectin Domain Family 1, Member B Antikörper (130) und C-Type Lectin Domain Family 1, Member B Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CLEC1B 51266 Q9P126
Anti-Maus CLEC1B CLEC1B 56760 Q9JL99
Anti-Ratte CLEC1B CLEC1B 500336  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 1.22 ng/mL 1.229-300 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$480.70
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Weitere ELISA Kits für C-Type Lectin Domain Family 1, Member B Interaktionspartner

Human C-Type Lectin Domain Family 1, Member B (CLEC1B) Interaktionspartner

  1. CLEC-2 may have a role in unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma

  2. CLEC-2 and P2Y12 (zeige P2RY12 ELISA Kits) are required for CpG ODN-induced platelet activation and thrombosis, and might be targeted to prevent adverse events in patients at risk.

  3. the CHIP/CLEC-2 axis may play an important role in the modulation of immune response.

  4. Data (including data from studies using cells from knockout mice) suggest that CLEC2/CLEC2R signaling is dependent on thromboxane A2 generation and is potentiated by co-stimulation with different GNAQ agonists. (CLEC2 = C-type lectin CLEC2; CLEC2R = CLEC2 receptor; GNAQ = guanine nucleotide-binding protein G[q] subunit alpha)

  5. NZ-1 inhibits the hPDPN-CLEC-2 interaction and is also useful for anti-PA tag MAb.The minimum epitope of LpMab-13 was identified as Ala42-Asp49 of hPDPN using Western blot and flow cytometry. The combination of different epitope-possessing MAbs could be advantageous for the hPDPN-targeting diagnosis and therapy

  6. CLEC2 prevents expression of PI3K (zeige PIK3CA ELISA Kits) subunits, in a SYK (zeige SYK ELISA Kits)-dependent manner, to suppress the invasive activities of gastric cancer cells.

  7. CLEC-2 regulates Akt and MAPK downstream of PI3K and PKC, leading to phosphorylation and inhibition of GSK3alpha/beta, and enhanced platelet aggregation and secretion.

  8. Data (including data from studies using recombinant proteins) suggest that a diverse range of ligands activate platelets through activation/phosphorylation (zeige CD36 ELISA Kits) of C (zeige GP6 ELISA Kits)D36/GPVI (glycoprotein VI) and/or CLEC-2 (C-type lectin-like receptor-2).

  9. PI3K (zeige PIK3CA ELISA Kits) and Tec (zeige NR4A3 ELISA Kits) family kinases play a crucial role in the regulation of platelet activation and Syk (zeige SYK ELISA Kits) phosphorylation downstream of the CLEC-2 receptor

  10. fucoidan is a novel CLEC-2 receptor agonist that activates platelets through a SFK-dependent signaling pathway

Mouse (Murine) C-Type Lectin Domain Family 1, Member B (CLEC1B) Interaktionspartner

  1. CLEC-2 and P2Y12 (zeige P2RY12 ELISA Kits) are required for CpG ODN-induced platelet activation and thrombosis, and might be targeted to prevent adverse events in patients at risk.

  2. CLEC-2 was involved in hepatic regeneration after liver resection and was attributed to the interaction between platelets and sinusoidal endothelial cells.

  3. CLEC-2 deficiency may inhibit thrombus formation in tumor vessels and increase the density of functional vessels, thus improving oxygen and nutrient supply to tumors, indirectly promoting tumor proliferation

  4. these data suggest that the platelet CLEC-2-podoplanin (zeige PDPN ELISA Kits) signaling axis regulates the severity of lung inflammation in mice and is a possible novel target for therapeutic intervention in patients at risk of developing ARDS.

  5. a hemITAM signaling-independent role for CLEC-2 in hemostasis and thrombosis

  6. a novel mechanism of Deep vein thrombosis, whereby CLEC-2 and upregulation of podoplanin (zeige PDPN ELISA Kits) expression in the venous wall trigger thrombus formation

  7. A reciprocal interaction between CLEC-2 on megakaryocytes and PDPN (zeige PDPN ELISA Kits) on Bone marrow (BM) Fibroblastic reticular cell-like cells contributes to the periarteriolar megakaryopoietic microenvironment in mouse BM.

  8. A role for CLEC2 as a regulator of macrophage polarity and Kupffer cell polarity, lipid and glucose homeostasis

  9. Data indicate that C-type lectin-like receptor-2 (CLEC-2) is highly expressed on bone marrow megakaryocytes (Mks (zeige MKKS ELISA Kits)).

  10. Data (including data from studies in transgenic mice) suggest that a diverse range of ligands activate platelets through activation/phosphorylation of Cd36 (zeige CD36 ELISA Kits)/GPVI (zeige GP6 ELISA Kits) (glycoprotein VI) and/or Clec-2 (C-type lectin-like receptor-2).

C-Type Lectin Domain Family 1, Member B (CLEC1B) Antigen-Profil

Beschreibung des Gens

Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1\; MIM 602894) and NKG2D (KLRC4\; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000

Genbezeichner und Symbole assoziert mit CLEC1B

  • C-type lectin domain family 1 member B (CLEC1B) Antikörper
  • C-type lectin domain family 1, member b (Clec1b) Antikörper
  • C-type lectin domain family 1, member B (Clec1b) Antikörper
  • C-type lectin domain family 1, member B (CLEC1B) Antikörper
  • C-type lectin domain family 1 member B (Clec1b) Antikörper
  • 1810061I13Rik Antikörper
  • Clec-2 Antikörper
  • CLEC1B Antikörper
  • Clec2 Antikörper
  • CLEC2B Antikörper
  • CLEC9A Antikörper
  • PRO1384 Antikörper
  • QDED721 Antikörper
  • RGD1563517 Antikörper

Bezeichner auf Proteinebene für CLEC1B

C-type lectin domain family 1 member B , C-type lectin-like receptor 2 , C-type lectin-like receptor-2 , CLEC-2 , C-type lectin domain family 1, member B , c-type lectin domain family 1 member B-like , C-type lectin domain containing 9A , C-type lectin domain family 9 member A

GENE ID SPEZIES
51266 Homo sapiens
56760 Mus musculus
465283 Pan troglodytes
500336 Rattus norvegicus
784092 Bos taurus
100346882 Oryctolagus cuniculus
717404 Macaca mulatta
100726289 Cavia porcellus
100053758 Equus caballus
611394 Canis lupus familiaris
101119293 Ovis aries musimon
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