anti-Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Antikörper

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human BLOC1S1 BLOC1S1 2647 P78537
Anti-Ratte BLOC1S1 BLOC1S1 288785 D3ZKU7
Anti-Maus BLOC1S1 BLOC1S1 14533 O55102
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Top anti-BLOC1S1 Antikörper auf antikoerper-online.de

Showing 10 out of 20 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  BLOC1S1  Sample Type:  Lung Tumor lysates  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: BLOC1S1 Antibody [NBP1-88583] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells. Immunohistochemistry-Paraffin: BLOC1S1 Antibody  - Staining of human duodenum shows cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen FITC ELISA, IHC, IHC (p), WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$581.17
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Human Kaninchen Biotin ELISA, IHC, IHC (p), WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$581.17
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Human Kaninchen HRP ELISA, IHC, IHC (p), WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$581.17
Details
Rind (Kuh) Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert ELISA, WB   150 μL Anmelden zum Anzeigen 13 bis 16 Tage
$753.50
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Human Kaninchen Unkonjugiert ELISA, WB   50 μL Anmelden zum Anzeigen 11 bis 16 Tage
$383.76
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Maus Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details

Weitere Antikörper gegen BLOC1S1 Interaktionspartner

Human Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Interaktionspartner

  1. Using cancer cell lines, the study shows that BLOC1S1 mRNA is specifically cleaved by IRE1 (zeige ERN1 Antikörper) at guanine 444, but only under conditions of IRE1 (zeige ERN1 Antikörper) hyperactivation.

  2. The Hermansky-Pudlak syndrome complex BLOC-1 and its cargo PI4KIIalpha interact with regulators of the actin cytoskeleton.

  3. BLOS1 interacts with KXD1.

  4. GCN5L1/BLOC1S1 regulates lysine acetylation in mitochondria.

  5. Quantitative proteomic studies expand the functional repertoire of the BLOC-1 complex and provide insight into putative molecular pathways of schizophrenia susceptibility.

  6. Together this study data provide evidence for the involvement of the BLOC-1 protein complex in SZ pathogenesis.

  7. Experimental investigation of five specific genes, AP3B1 (zeige AP3B1 Antikörper), ATP6AP1 (zeige ATP6AP1 Antikörper), BLOC1S1, LAMP2 (zeige LAMP2 Antikörper), and RAB11A (zeige RAB11A Antikörper), has confirmed novel roles for these proteins in the proper initiation of macroautophagy in amino acid-starved fibroblasts.

  8. Biogenesis of Lysosome-related Organelles co (zeige SNAPIN Antikörper)mplex-1 (BLOC-1) subunit 1 (BLOS1).

Mouse (Murine) Biogenesis of Lysosomal Organelles Complex-1, Subunit 1 (BLOC1S1) Interaktionspartner

  1. Data show that the mitochondrial enriched GCN5 (zeige KAT2A Antikörper)-like 1 protein (GCN5L1) controls hepatic glucose production by regulating FoxO1 (zeige FOXO1 Antikörper) protein levels.

  2. Acetylation of cardiac mitochondrial fatty acid oxidation enzymes by GCN5L1 significantly upregulates their activity in diet-induced obese mice.

  3. TDH, responsible for mitochondrial production of acetyl-CoA (zeige LPCAT1 Antikörper) in mouse embryonic stem cells, and the acetyltransferase GCN5L1 cooperate to acetylate Lys501 in KBP, allowing its recognition by and degradation via Fbxo15 (zeige FBXO15 Antikörper), an F-box protein (zeige FBXO30 Antikörper) transcriptionally controlled by the pluripotency core factors and repressed following differentiation.

  4. BLOS1 interacts with sorting nexin 2 (zeige SNX2 Antikörper) and the ESCRT-I (zeige VPS28 Antikörper) component TSG101 (zeige TSG101 Antikörper) to mediate the sorting of EGFR (zeige EGFR Antikörper) into endosomal compartments

  5. Here we show that genetic deletion of GCN5L1 has a direct positive effect on the expression and activity of Transcriptional Factor EB (TFEB (zeige TFEB Antikörper)), which acts as a master regulator of autophagy.

  6. Mutations in the human genes encoding Snapin (zeige SNAPIN Antikörper) and the BLOS proteins could underlie novel forms of Hermansky-Pudlak syndrome as seen in mouse models

  7. Defects in all the 5 known components of BLOC-1 (zeige PLDN Antikörper), including RP, cause severe Hermansky Pudlak syndrome in mice, suggesting that the subunits are nonredundant and that BLOC-1 (zeige PLDN Antikörper) plays a key role in organelle biogenesis.

  8. These results indicate that the BLOC-1 (zeige PLDN Antikörper) and AP-3 (zeige AP3B1 Antikörper) protein complexes affect the targeting of SNARE (zeige VTI1B Antikörper) and non-SNARE (zeige VTI1B Antikörper) AP-3 (zeige AP3B1 Antikörper) cargoes and suggest a function of the BLOC-1 (zeige PLDN Antikörper) complex in membrane protein sorting.

BLOC1S1 Antigen-Profil

Protein Überblick

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004

Genbezeichner und Symbole assoziert mit BLOC1S1

  • biogenesis of lysosomal organelles complex 1 subunit 1 (BLOC1S1) Antikörper
  • biogenesis of lysosomal organelles complex-1, subunit 1 (Bloc1s1) Antikörper
  • AI839753 Antikörper
  • BLOS1 Antikörper
  • Gcn5l1 Antikörper
  • MICoA Antikörper
  • RT14 Antikörper

Bezeichner auf Proteinebene für BLOC1S1

BLOC subunit 1 , BLOC-1 subunit 1 , GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1 , GCN5 general control of amino-acid synthesis 5-like 1 , GCN5-like protein 1 , MTA1-interacting coactivator , biogenesis of lysosome-related organelles complex 1 subunit 1 , biogenesis of lysosome-related organelles complex-1, subunit 1 , GCN5 general control of amino acid synthesis-like 1 , general control of amino acid synthesis, yeast homolog-like 1 , general control of amino acid synthesis-like 1

GENE ID SPEZIES
2647 Homo sapiens
615149 Bos taurus
288785 Rattus norvegicus
100190807 Pongo abelii
14533 Mus musculus
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