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The protein encoded by BANK1 is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. Zusätzlich bieten wir Ihnen BANK1 Antikörper (27) und BANK1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
The pre-B-cell receptor (pre-BCR (zeige BCR ELISA Kits)) signaling molecules BLNK (zeige BLNK ELISA Kits), BTK (zeige BTK ELISA Kits) and BANK1 were positively regulated by the ZFP521 gene, leading to enhancement of the pre-BCR (zeige BCR ELISA Kits) signaling pathway.
Following CpG stimulation of B-cells, BANK1 loss reduced p38 (zeige CRK ELISA Kits) phosphorylation (but not ERK (zeige EPHB2 ELISA Kits) or JNK (zeige MAPK8 ELISA Kits)), IL-6 (zeige IL6 ELISA Kits) secretion, & MNK1 (zeige MKNK1 ELISA Kits)/2 and eIF4E (zeige EIF4E ELISA Kits) phosphorylation. It had no effect on IL-6 (zeige IL6 ELISA Kits) mRNA stability. BANK1 does not affect release of eIF4E (zeige EIF4E ELISA Kits) by phospho-4E-BP1 (zeige EIF4EBP1 ELISA Kits).
BANK attenuates CD40 (zeige CD40 ELISA Kits)-mediated Akt (zeige AKT1 ELISA Kits) activation, thereby preventing hyperactive B cell responses.
Confirm the association of rs548234/ATG5, rs2736340/BLK and rs10516487/BANK1 with systemic lupus erythematosus in Chinese Han and reinforced our hypothesis of their epistasis effect in regulating B-cell signaling in SLE.
The results of this study suggesting a mechanism for the involvement of BANK1 in the BOLD response to working memory
Single-nucleotide polymorphism in BANK1 gene is associated with sclerotic graft-versus-host disease.
The SLE susceptibility variants in the BANK1 gene may contribute to lupus by altering B cell signaling, increasing FOXO1 (zeige FOXO1 ELISA Kits) levels, and enhancing memory B cell development
The systemic lupus erythematosus variant Ala71Thr of BLK (zeige BLK ELISA Kits) severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain (zeige ITSN1 ELISA Kits) function.
Data show that single-nucleotide polymorphism rs3733197 located in the coding region of BANK1 (B-cell scaffold protein with ankyrin repeats 1) was significantly associated with serum LDL cholesterols.
Authors identified a novel balanced reciprocal translocation, t(4;14)(q24;q32.) Sequence analysis identified the partner gene as BANK1.
Our study confirms evidence for epistasis between BLK (zeige BLK ELISA Kits) and BANK1 in systemic lupus erythematosis from a Chinese population for the first time.
Our findings suggest the existence of association between BANK1 gene and autoimmune thyroid diseases
BANK1 and IL15 (zeige IL15 ELISA Kits) as new T1D genetic susceptibility factors.
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
B-cell scaffold protein with ankyrin repeats
, B-cell scaffold protein with ankyrin repeats 1
, B-cell scaffold protein with ankyrin repeats 1 delta 2 transcript
, B-cell scaffold protein with ankyrin repeats-like
, b-cell scaffold protein with ankyrin repeats-like