Atrophin 1 (ATN1) ELISA Kits

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. Zusätzlich bieten wir Ihnen Atrophin 1 Antikörper (36) und Atrophin 1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ATN1 1822 P54259
ATN1 13498 O35126
ATN1 29515 P54258
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Top Atrophin 1 ELISA Kits auf antikoerper-online.de

Showing 3 out of 6 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
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Ratte < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
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Human < 0.19 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details

Weitere ELISA Kits für Atrophin 1 Interaktionspartner

Human Atrophin 1 (ATN1) Interaktionspartner

  1. Data indicate that the size of the expanded CAG repeats od dentatorubral-pallidoluysian atrophy protein (DRPLA) was inversely correlated with the age at onset.

  2. Epigenetic regulation of ATN1 by LSD1 (zeige KDM1A ELISA Kits) is required for cortical progenitor maintenance.

  3. Juvenile myoclonic epilepsy is not associated with the DRPLA gene in a European population.

  4. These data demonstrate that the expanded trinucleotide repeat within ATN-1 mRNA is a potential target for compounds designed to achieve allele-selective inhibition of ATN-1 protein, and one agent may allow the targeting of multiple disease genes.

  5. results suggest that expanded polyQ repeats in ATN1 may contribute to neurodegeneration via alterations in both protein aggregation and intracellular localization.

  6. This study demonistrated that hypoalbuminemia in early onset DRPLA revealed the possibility of multiorgan involvement.

  7. In cerebrum and cerebellum of DRPLA transgenic mouse lines at 4, 8, and 12 weeks it is demonstrated that both the number and expression levels of the altered genes are highly dependent on CAG repeat (zeige CELF3 ELISA Kits) length and age in both brain regions.

  8. This study demonistrated that Atn1 is response for Dentatorubral-pallidoluysian atrophy.

  9. This sttudy suggested that age-dependent and CAG repeat (zeige CELF3 ELISA Kits)-dependent intranuclear accumulation of mutant DRPLA leading to nuclear dysfunctions are suggested to be the essential pathophysiologic mechanisms in Dentatorubral-pallidoluysian atrophy.

  10. Atrophin-1 promote neurodegeneration with autophagic hallmarks both in neuronal photoreceptors and glial cells.

Mouse (Murine) Atrophin 1 (ATN1) Interaktionspartner

  1. These results support the model that poly-Q expanded Atrophin-1 proteins cause dentatorubral-pallidoluysian atrophy in a manner independent of any functional interaction with wild-type Atrophin-1 proteins.

  2. TLX interacts with atrophin1 (Atn1), a corepressor that is involved in human neurodegenerative dentatorubral-pallidoluysian atrophy (DRPLA) and that is essential for development of multiple tissues.

  3. Atrophin-1 and the short form of Atrophin-2 (zeige RERE ELISA Kits) can act as potent and evolutionarily conserved transcriptional activators.

  4. Fat1 and Atrs 1,2 act in concert after vascular injury but show further that distinct Atr isoforms have disparate effects on VSMC directional migration.

Atrophin 1 (ATN1) Antigen-Profil

Beschreibung des Gens

Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-23 copies to 49-75 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.

Genbezeichner und Symbole assoziert mit Atrophin 1 (ATN1) ELISA Kits

  • atrophin 1 (ATN1) Antikörper
  • atrophin 1 (Atn1) Antikörper
  • ATN1 Antikörper
  • Atr1 Antikörper
  • atrophin-1 Antikörper
  • B37 Antikörper
  • D12S755E Antikörper
  • Drpla Antikörper
  • HRS Antikörper
  • NOD Antikörper
  • RERE Antikörper

Bezeichner auf Proteinebene für Atrophin 1 (ATN1) ELISA Kits

atrophin-1 , dentatorubral-pallidoluysian atrophy protein , dentatorubral pallidoluysian atrophy , dentatorubral-pallidoluysian atrophy protein homolog , arginine-glutamic acid dipeptide (RE) repeats , atrophin 1

GENE ID SPEZIES
1822 Homo sapiens
13498 Mus musculus
29515 Rattus norvegicus
427946 Gallus gallus
451803 Pan troglodytes
513125 Bos taurus
722114 Macaca mulatta
100349239 Oryctolagus cuniculus
100599977 Nomascus leucogenys
611607 Canis lupus familiaris
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