Ataxin 10 Proteine (ATXN10)

ATXN10 encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis.

alle Proteine anzeigen Gen GeneID UniProt
Human ATXN10 ATXN10 25814 Q9UBB4
Ratte ATXN10 ATXN10 170821 Q9ER24
Maus ATXN10 ATXN10 54138 P28658
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Hefe Cynomolgus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,340.33
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,340.33
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,340.33
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Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,371.50
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Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$688.00
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Escherichia coli (E. coli) Maus Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
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Weitere Proteine zu Ataxin 10 (ATXN10) Interaktionspartnern

Human Ataxin 10 (ATXN10) Interaktionspartner

  1. Polymorphism in ATXN10 gene is associated with spinocerebellar ataxia type 10.

  2. Inheritance patterns of ATCCT repeat interruptions in spinocerebellar ataxia type 10 expansions of ataxin-10 has been reported.

  3. Single molecule real time sequencing of long tandem nucleotide repeats in spinocerebellar ataxia ATXN10 reveals unique insight of repeat expansion structure in three unrelated patients.

  4. This is the first description of a family with two SCA mutations with affected subjects having a combined SCA2 (zeige LY6E Proteine) and SCA10 phenotype.

  5. Inhibition of Aurora B or expression of the S12A mutant renders reduced interaction between Ataxin-10 and polo-like kinase 1 (Plk1), a kinase previously identified to regulate Ataxin-10 in cytokinesis.

  6. Data suggest precursor mRNA for SCA10 (crystalized using two model AUUCU SCA10 repeats) exhibits the following conformation: the two asymmetric RNA molecules are antiparallel to each other and the interaction is stabilized by multiple hydrogen bonds.

  7. the presence of repeat interruptions in SCA10 repeat expansion may have a role in epilepsy phenotype

  8. The SCA10 pentanucleotide repeat expansion was not found among a group of Cypriot ataxia patients. All had 10-19 ATTCT repeats. Controls had 11-20 repeats, with 14 being the most common number.

  9. Plk1 phosphorylates Ataxin-10 on Ser (zeige SIGLEC1 Proteine) 77 and Thr (zeige TRH Proteine) 82.

  10. The expansion of the attct repeat in intron 9 of atxn10 is may caused Spinocerebellar ataxia type 10.

Mouse (Murine) Ataxin 10 (ATXN10) Interaktionspartner

  1. Ataxin-10, encoded by the SCA10 gene, interacts with O-linked N-acetylglucosamine in vivo and is modified by O-linked glycosylation in the insulinoma (zeige RPS15 Proteine) MIN6 cell line.

Ataxin 10 (ATXN10) Protein Überblick

Protein Überblick

This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of a pentanucleotide repeat in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit Ataxin 10 Proteine (ATXN10)

  • ataxin 10 (ATXN10)
  • ataxin 10 (atxn10)
  • ataxin 10 (Atxn10)
  • AI325283 Protein
  • Ataxin-10 Protein
  • atxn10 Protein
  • C77170 Protein
  • E46 Protein
  • E46L Protein
  • HUMEEP Protein
  • MGC97716 Protein
  • Sca10 Protein
  • si:dkeyp-15g12.2 Protein
  • TEG-169 Protein
  • Tex169 Protein

Bezeichner auf Proteinebene für Ataxin 10 Proteine (ATXN10)

ataxin 10 , MGC97716 protein , Spinocerebellar ataxia type 10 protein homolog , ataxin-10 , brain protein E46 homolog , spinocerebellar ataxia type 10 protein , ataxin 10 homolog , neuronal beta-catenin-like protein , spinocerebellar ataxia 10 homolog , spinocerebellar ataxia type 10 protein homolog , brain protein E46 , spinocerebellar ataxia 10 , testis expressed gene 169 , spinocerbellar ataxia type 10 protein-like protein

GENE ID SPEZIES
418245 Gallus gallus
470238 Pan troglodytes
474467 Canis lupus familiaris
548542 Xenopus (Silurana) tropicalis
713805 Macaca mulatta
100034473 Danio rerio
100171821 Pongo abelii
100607798 Nomascus leucogenys
25814 Homo sapiens
170821 Rattus norvegicus
54138 Mus musculus
767990 Bos taurus
414389 Sus scrofa
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