Asparagine-Linked Glycosylation 1, beta-1,4-Mannosyltransferase Homolog (S. Cerevisiae) Proteine (ALG1)

The enzyme encoded by ALG1 catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. Zusätzlich bieten wir Ihnen Asparagine-Linked Glycosylation 1, beta-1,4-Mannosyltransferase Homolog (S. Cerevisiae) Antikörper (31) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ALG1 56052 Q9BT22
ALG1 208211 Q921Q3
Ratte ALG1 ALG1 360475  
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
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Hefe Schizosaccharomyces pombe His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
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Hefe Yeast His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,259.67
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ALG1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, , ,
Mouse (Murine)
,

Weitere Proteine zu Asparagine-Linked Glycosylation 1, beta-1,4-Mannosyltransferase Homolog (S. Cerevisiae) (ALG1) Interaktionspartnern

Human Asparagine-Linked Glycosylation 1, beta-1,4-Mannosyltransferase Homolog (S. Cerevisiae) (ALG1) Interaktionspartner

  1. evaluated the genetic association of WDR3 and ALG1 in schizophrenia. We examined 21 single nucleotide polymorphisms [SNPs; W1 (rs1812607)-W16 (rs6656360), A1 (rs8053916)-A10 (rs9673733)] from these genes using the Japanese case-control sample (1,808 schizophrenics and 2,170 matched controls). No significant genetic associations of these SNPs were identified. However, we detected a significant association of W4 (rs319471)

  2. Study presents molecular, clinical and biochemical findings in the largest collection of ALG1-CDG cases ever reported at a single time with 39 cases, bringing the total number to 57. This ranks it the third most common CDG type behind PMM2 (zeige PMM2 Proteine)-CDG and ALG6 (zeige ALG6 Proteine)-CDG. In addition, highly lethal genotype were identified and confirm the presence of a unique xeno-tetrasaccharide in ALG1-CDG patients.

  3. Was detected in the patient's ALG1-coding sequence.

  4. Family study defining the phenotype of deficiency of beta-1,4 mannosyltransferase (MT-1) congenital disorder of glycosylation (CDG), due to ALG1 gene mutations. Four novel ALG1 mutations were identified.

  5. DNA sequencing of ALG1 revealed nine different mutations, seven of which have not been previously reported. Clinical presentations of deficiency are severe, with dysmorphias, CNS involvement and ocular disturbances

Asparagine-Linked Glycosylation 1, beta-1,4-Mannosyltransferase Homolog (S. Cerevisiae) (ALG1) Protein Überblick

Protein Überblick

The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik.

Genbezeichner und Symbole assoziert mit ALG1

  • ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1)
  • asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase) (Alg1)
  • ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase (alg1)
  • ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase (Alg1)
  • Beta-mannosyltransferase (ALG1)
  • CDG1K Protein
  • hMat-1 Protein
  • HMAT1 Protein
  • HMT-1 Protein
  • HMT1 Protein
  • Mat-1 Protein
  • MT-1 Protein
  • wu:fi34b12 Protein
  • zgc:66221 Protein

Bezeichner auf Proteinebene für ALG1

GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase , GDP-mannose-dolichol diphosphochitobiose mannosyltransferase , asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase) , asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog , asparagine-linked glycosylation protein 1 homolog , beta-1,4 mannosyltransferase , beta-1,4-mannosyltransferase , chitobiosyldiphosphodolichol beta-mannosyltransferase , mannosyltransferase-1 , asparagine-linked glycosylation 1 homolog (S. cerevisiae, beta-1,4-mannosyltransferase) , hypothetical protein

GENE ID SPEZIES
56052 Homo sapiens
208211 Mus musculus
334161 Danio rerio
360475 Rattus norvegicus
3646537 Candida albicans SC5314
100723491 Cavia porcellus
416393 Gallus gallus
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