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ARMCX1 encodes a member of the ALEX family of proteins and may play a role in tumor suppression.
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It is suggested that the ALEX1 protein is associated with tumorigenesis in cervical cancer and we speculate that the ALEX1 may plays a role as an oncogene (zeige RAB1A Antikörper) in cervical cancer.
ALEX1 is a crucial tumor suppressor gene involved in cell proliferation and apoptosis in breast cancer.
Findings suggest that overexpression of ALEX1 (armadillo (zeige PKP1 Antikörper) repeat containing, X-linked [ARMCX]) plays a negative role in colorectal tumorigenesis.
Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB (zeige CREB1 Antikörper) and Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling.
Armcx1 is upregulated after axotomy in a model with robust regeneration. Armcx1 overexpression enhances mitochondrial transport in adult retinal ganglion cells. Armcx1 also promotes both neuronal survival and axon regeneration after injury, and these effects depend on its mitochondrial localization.
This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.
ARM protein lost in epithelial cancers on chromosome X 1
, arm protein lost in epithelial cancers, X chromosome, 1
, armadillo repeat-containing X-linked protein 1
, armadillo repeat containing, X-linked 1
, Armadillo repeat-containing X-linked protein 1
, armadillo repeat-containing X-linked protein 1-like