anti-Arachidonate 5-Lipoxygenase (ALOX5) Antikörper

ALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. Zusätzlich bieten wir Ihnen ALOX5 Kits (67) und ALOX5 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ALOX5 240 P09917
ALOX5 11689 P48999
ALOX5 25290 P12527
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Top anti-ALOX5 Antikörper auf antikoerper-online.de

Showing 10 out of 200 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Huhn Maus Unkonjugiert IF, IP, IHC, WB Western blot analysis of 5-Lipoxygenase on SL-29 lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilultion of 5-Lipoxygenase. Immunofluorescence staining of A431 cells 150 μg Anmelden zum Anzeigen 6 bis 8 Tage
$305.54
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185698 (0.3µg/ml) staining of Rat Stomach lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-ALOX5 Picoband antibody,  IHC(P): Mouse Brain Tissue Anti-ALOX5 Picoband antibody,  IHC(P): Rat Brain Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using Arachidonate 5 Lipoxygenase (Ab-271) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Arachidonate 5 Lipoxygenase (Ab-271) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (fro), IHC (p), WB Immunohistochemistry: 5-Lipoxygenase Antibody [ABIN42769118] - Immunohistochemistry (IHC) analyzes of ALOX5 (E267) antibody in paraffin-embedded human skeletal muscle tissue. Western Blot: 5-Lipoxygenase Antibody [ABIN42769118] - Western blot (WB) analysis of ALOX5 (E267) antibody in extracts from HuvEc cells 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$490.19
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HuvEc cells, using Arachidonate 5 Lipoxygenase (Phospho-Ser271) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using Arachidonate 5 Lipoxygenase (Phospho-Ser271) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ICC, IF, SimWes, WB Detection of LOX5 in human peripheral leukocytes using ABIN258593 at 0.5(Lane 1) and 2.0 ug/ml (Lane 2). Simple Western: 5-Lipoxygenase Antibody [ABIN2585938] - Simple Western lane view shows a specific band for 5-Lipoxygenase in 0.5 mg/ml of Human Lung lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. * Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Human Placenta Tissue. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$332.00
Details
Rind (Kuh) Kaninchen Unkonjugiert SimWes, WB Detection of LOX5 in human peripheral leukocytes using ABIN258596 at 0.5(Lane 1) and 2.0 ug/ml (Lane 2). Simple Western: 5-Lipoxygenase Antibody [ABIN2585969] - Simple Western lane view shows a specific band for 5-Lipoxygenase in 0.5 mg/ml of Human Lung lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. * Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details

ALOX5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-ALOX5 Antikörper

  1. Chicken Monoclonal ALOX5 Primary Antibody für IF, IP - ABIN968116 : Hundley, Prasad, Beaven: Elevated levels of cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 5 Pubmed References

  2. Chicken Monoclonal ALOX5 Primary Antibody für IF, IP - ABIN968117 : Lepley, Fitzpatrick: 5-Lipoxygenase contains a functional Src homology 3-binding motif that interacts with the Src homology 3 domain of Grb2 and cytoskeletal proteins. in The Journal of biological chemistry 1994 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal ALOX5 Primary Antibody für IF (p), IHC (p) - ABIN669651 : Wang, Wang, Gao, Qu: The comparative study of acetyl-11-keto-beta-boswellic acid (AKBA) and aspirin in the prevention of intestinal adenomatous polyposis in APC(Min/+) mice. in Drug discoveries & therapeutics 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal ALOX5 Primary Antibody für ICC, IF - ABIN4276911 : Ohkubo, Ito, Minamino, Mishima, Hirata, Hosono, Shibuya, Yokomizo, Shimizu, Watanabe, Majima: Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ALOX5 Primary Antibody für IHC, ELISA - ABIN1532500 : Mancini, Ortiz, Croxatto, Gallo: Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet. in BMC ophthalmology 2013 (PubMed)

  6. Human Polyclonal ALOX5 Primary Antibody für ICC, IF - ABIN258593 : Lin, Lin, Wu, Chiu, Tang, Hour, Liou, Tu, Yang, Fu: 5-Lipoxygenase inhibitors attenuate TNF-α-induced inflammation in human synovial fibroblasts. in PLoS ONE 2014 (PubMed)

  7. Human Polyclonal ALOX5 Primary Antibody für ELISA, WB - ABIN251668 : Kalayci, Birben, Sackesen, Keskin, Tahan, Wechsler, Civelek, Soyer, Adalioglu, Tuncer, Israel, Lilly: ALOX5 promoter genotype, asthma severity and LTC production by eosinophils. in Allergy 2005 (PubMed)

Weitere Antikörper gegen ALOX5 Interaktionspartner

Human Arachidonate 5-Lipoxygenase (ALOX5) Interaktionspartner

  1. Data suggest that the co-carcinogens benzidine and hydrogen peroxide induce expression of ALOX5 mRNA and protein in tracheobronchial epithelial cells; the co-carcinogens decrease cell proliferation but enhance apoptosis, actions inhibited by knockdown of ALOX5 by RNA interference. Benzidine appears to undergo metabolic activation to benzidine diimine by ALOX5.

  2. This study revealed that epistatic interaction among the ALOX5, ALOX5AP (zeige ALOX5AP Antikörper) and MPO (zeige MPO Antikörper) genes played a significant role in vulnerability to ischemic stroke.

  3. The anticancer effects by 13'-COOHs appeared to be partially independent of inhibition of COX-2/5-LOX. Using liquid chromatography tandem mass spectrometry, we found that 13'-COOHs increased intracellular dihydrosphingosine and dihydroceramides after short-time incubation in HCT-116 cells, and enhanced ceramides while decreased sphingomyelins during prolonged treatment

  4. ROS (zeige ROS1 Antikörper) production induced by the 5-LO pathway mediates the anti-cancer effects of docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine on head and neck squamous cell carcinoma cells.

  5. Specific inhibitors of COX-2 (zeige COX2 Antikörper) and 5-LOX decreased formation of HKD2 and HKE2 (zeige PFDN6 Antikörper) Platelets did not form HKs from exogenous 5S-hydroxyeicosatetraenoic acid, implying that COX-1 (zeige COX1 Antikörper) is not involved

  6. The observation that the coexpression of FLAP (zeige ALOX5AP Antikörper) with a subset of the 5-LOX mutants restores 5-LOX-wild-type (wt)-like levels of products formed in intact cells suggests a physical protein-protein interaction, beyond colocalization, of 5-LOX and FLAP (zeige ALOX5AP Antikörper).

  7. Polymorphisms in the 5-Lipoxygenase is associated with Incident Myocardial Infarction.

  8. our results define Alox5 as a key genetic effector of JAK2V617F in driving polycythemia vera (zeige IGF2BP3 Antikörper)

  9. Adipose tissue eicosapentaenoic acid and arachidonic acid and the ALOX-5 tandem repeat polymorphism did not significantly interact to affect the risk of myocardial infarction.

  10. coexpression of the isoforms inhibited or stimulated 5-LO-WT expression in transiently and stably transfected HEK293T cells suggesting that the isoforms have other functions than canonical leukotriene biosynthesis

Mouse (Murine) Arachidonate 5-Lipoxygenase (ALOX5) Interaktionspartner

  1. Our data showed that besides the high parasite burden and lack of microbicidal molecules, an imbalance with high COX-2 (zeige COX2 Antikörper) and 5-LOX eicosanoid expression and a lack of regulatory PPAR-gamma (zeige PPARG Antikörper) cytoplasm-to-nucleus translocation in macrophages were observed in mice that develop cerebral malaria.

  2. Data indicate that 5-lipoxygenase (5-LO)/leukotriene B4 (LTB4 (zeige PTGR1 Antikörper)) axis orchestrates graft-versus-host disease (GVHD) development and suggest it could be a target for the development of therapeutic strategies for GVHD treatment.

  3. Findings demonstrate that the up-regulation of the ALOX5 gene pathway is responsible for the development of the biochemical and behavioral sequelae of high Hcy brain levels in the context of a neurodegenerative phenotype.

  4. This study demonstrates that LTB4 (zeige PTGR1 Antikörper) promotes macrophage phagocytosis of bacteria via BLT1, and that BLT2 (zeige LTB4R2 Antikörper) can fulfill this role in the absence of BL

  5. our results define Alox5 as a key genetic effector of JAK2V617F in driving polycythemia vera (zeige IGF2BP3 Antikörper)

  6. Homocysteine directly influences 5LO expression levels and establish a previously unknown cross talk between these two pathways.

  7. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (zeige YWHAZ Antikörper), lipoxygenase and cyclooxygenase.

  8. Data suggest that miR (zeige MLXIP Antikörper)-674-5p (microRNA-674-5p) serves as a negative regulator in 5-LO (arachidonate 5-lipoxygenase) mediated autoimmune liver injury; miR (zeige MLXIP Antikörper)-674-5p represses expression of 5-LO in hepatocytes in the presence of IL-6 (interleukin-6 (zeige IL6 Antikörper)) or TNFa (tumor necrosis factor-alpha (zeige TNF Antikörper)).

  9. Results establish a key role of 5-Lipoxygenase in the development of the tau pathology phenotype and demonstrate it to be a novel viable therapeutic target for the pharmacologic treatment of human tauopathy.

  10. GSAP (zeige PION Antikörper) cleavage via caspase-3 (zeige CASP3 Antikörper) is regulated and depend upon the availability of 5-Lipoxygenase in Alzheimer's disease.

Horse (Equine) Arachidonate 5-Lipoxygenase (ALOX5) Interaktionspartner

  1. [5-lipoxygenase; 5-lox] protein expression and enzyme activity of 5-LOX were significantly higher in horses harbouring encysted larvae in comparison with horses free of encysted larvae

  2. Increased PGE2 production led to reduction in 5-LO products in LPS (zeige IRF6 Antikörper)-treated equine whole blood via IL-1b (zeige IL1B Antikörper).

ALOX5 Antigen-Profil

Protein Überblick

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit ALOX5

  • arachidonate 5-lipoxygenase (ALOX5) Antikörper
  • arachidonate 5-lipoxygenase (Alox5) Antikörper
  • arachidonate 5-lipoxygenase a (alox5a) Antikörper
  • arachidonate 5-lipoxygenase (AFUA_4G02770) Antikörper
  • arachidonate 5-lipoxygenase (AOR_1_1362014) Antikörper
  • Arachidonate 5-lipoxygenase (lox5) Antikörper
  • 5-LO Antikörper
  • 5-LOX Antikörper
  • 5LO Antikörper
  • 5LPG Antikörper
  • 5LX Antikörper
  • AI850497 Antikörper
  • F730011J02 Antikörper
  • LOG5 Antikörper
  • lox5 Antikörper
  • LOX5A Antikörper
  • si:dkey-194n13.2 Antikörper

Bezeichner auf Proteinebene für ALOX5

LOX-5 , arachidonic 5-lipoxygenase alpha-10 isoform , arachidonic 5-lipoxygenase delta-10-13 isoform , arachidonic 5-lipoxygenase delta-13 isoform , arachidonic 5-lipoxygenase delta-p10 isoform , arachidonic acid 5-lipoxygenase , leukotriene A4 synthase , 5-lipoxygenase , 5 - Lipoxygenase , 5-LO , LOX2 , arachidonate 5-lipoxygenase , Arachidonate 5-lipoxygenase

GENE ID SPEZIES
240 Homo sapiens
11689 Mus musculus
25290 Rattus norvegicus
404074 Bos taurus
477753 Canis lupus familiaris
567204 Danio rerio
3503886 Aspergillus fumigatus Af293
5994193 Aspergillus oryzae RIB40
100194803 Salmo salar
100718093 Cavia porcellus
423769 Gallus gallus
100156205 Sus scrofa
100341714 Oryctolagus cuniculus
101117390 Ovis aries
101839970 Mesocricetus auratus
100062042 Equus caballus
Ausgewählte Anbieter für anti-ALOX5 (ALOX5) Antikörper
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