anti-Annexin A2 (ANXA2) Antikörper

Horse (Equine) Annexin A2 (ANXA2) Interaktionspartner

1. ANXA2 and MMP1 (zeige MMP1 Antikörper) might participate in remodeling during wound healing in the horse.

Cow (Bovine) Annexin A2 (ANXA2) Interaktionspartner

1. AnxA2 functions as a critical regulator for amino acid or hormone-induced milk synthesis and mammary gland epithelial cell proliferation via the PI3K-mTOR (zeige FRAP1 Antikörper)-SREBP-1c (zeige SREBF1 Antikörper)/Cyclin D1 (zeige CCND1 Antikörper) signaling pathway.

2. annexin A2-induced actin bundling is apparently essential for generating active exocytotic sites.

3. Calves that later developed pneumonia had significantly lower levels of annexin A1 (zeige ANXA1 Antikörper) and annexin A2, which are potential biomarkers of increased susceptibility to pneumonia in recently weaned and transported feedlot cattle.

4. Because annexins I and II are abundant and have functions important to the maintenance of placentation, the down-regulation of the annexin genes in the cultured NT (nuclear transfer) trophectoderm may be related to the frequent failures of NT pregnancies.

5. annexin II binds to CEACAM1 (zeige CEACAM1 Antikörper) in a breast neoplasm model

6. show for the first time that annexin A2 (AIIt) can undergo functional reactivation by glutaredoxin (zeige GRX1 Antikörper), therefore establishing that AIIt is regulated by reversible glutathionylation

7. AII (zeige NLRP3 Antikörper) does not bind 1,25-D(3) in a physiologically relevant manner

8. Data show that the mRNA-binding site of Annexin A2 resides in its domain IV.

9. The results showed that alkaline phosphatase (ALP) activity was significantly increased in matrix vesicles from calcified bovine vascular smooth muscle cells (BVSMCs) compared with noncalcified BVSMCs, as was annexin II and VI content and (45)Ca uptake.

Human Annexin A2 (ANXA2) Interaktionspartner

1. Results show that Anxa2-Tyr23 phosphorylation is necessary for proliferation, invasion, and metastasis of breast cancer cells in vitro and in vivo. Tyr23-phosphorylated Anxa2 binds to STAT3 (zeige STAT3 Antikörper) and serves as a key regulator of STAT3 (zeige STAT3 Antikörper) signaling.

2. annexin A2 can potentially predict the development of pre-eclampsia. The low annexin A2 levels (<0.89 ng/ml) together with higher blood pressure and proteinuria constitute a higher risk to develop preeclampsia.

3. Variants in the Annexin A2 (ANXA2) gene directly influence plasma LDL-C levels.

4. this study showed that Annexin A2 inhibition suppresses proliferation and invasion in ovarian cancer via beta-catenin (zeige CTNNB1 Antikörper)/EMT (zeige ITK Antikörper), proposing the potential role of Annexin A2 in the prevention and treatment of ovarian cancer

5. FNDC3B (zeige FNDC3B Antikörper) and ANXA2 expression correlate negatively with patient survival in hepatocellular carcinoma

6. UBAP2 (zeige UBAP2 Antikörper) formed a complex with Annexin A2 and promoted the degradation of Annexin A2 protein by ubiquitination, and then inhibited HCC (zeige FAM126A Antikörper) progression.

7. results indicate that ANXA2 plays an important role to enhance the malignant behaviors of Hepatocellular carcinoma cells, and the enhancement is closely based on its remodeling to cell structures

8. Thus, tight regulation of AnxA2 function is an integral aspect of cellular homeostasis. The presence of AnxA2 in cancer cell-derived exosomes, as well as the potential regulation of exosomal AnxA2 by phosphorylation or other PTMs (zeige PTMS Antikörper), are topics of great interes

9. Restoration of miR (zeige MLXIP Antikörper)-101 expression reversed chemoresistance of drug-resistant gastric cancer cells by inhibiting viability and enhancing apoptosis via targeting ANXA2.

10. Annexin 2A (ANXA2) is over-expressed in Glioblastoma (GBM) and positively correlates with patient outcome.

Pig (Porcine) Annexin A2 (ANXA2) Interaktionspartner

1. In conclusion, Annexin 2 is the novel host protein identified to interact with classical swine fever virus E2 and promote virus multiplication.

2. Amino acids R338, N359, G378 of NS5A were revealed to be pivotal for the ANXA2-NS5A interaction.

3. Taken together, these results indicate that Nsp9 binding partner ANXA2 is beneficial for porcine reproductive and respiratory syndrome virus replication.

4. Annexin A2 acts in exocytic apical membrane trafficking in small intestinal enterocytes and is proteolytically cleaved in situ by pancreatic proteinases once it has become externalized to the lumenal side of the brush border membrane. [annexin A2]

5. An octameric model is proposed for the annexin A2/p11(S100A10 (zeige S100A10 Antikörper)) complex, which exerts annexin A2 function. The proposed structure of the annexin A2/p11 (zeige S100A10 Antikörper) octamer sheds new light into annexin A2/p11 (zeige S100A10 Antikörper) interaction.

Mouse (Murine) Annexin A2 (ANXA2) Interaktionspartner

1. Our data indicate that hepatic overexpression of ANX1 (zeige ANXA1 Antikörper) and ANX2 inhibits APAP-induced expansion of liver injury

2. This study indicated that AnxA2 played complex roles in traversal of C. neoformans across host brain microvascular endothelial cells.

3. contributes to pulmonary microvascular integrity by enabling vascular endothelial cadherin (zeige CDH5 Antikörper)-related phosphatase activity, thereby preventing vascular leak during alveolar hypoxia

4. our studies show that this G-motif represents a novel and essential determinant for axonal localization of the Anxa2 mRNA mediated by the SMN (zeige STMN1 Antikörper) complex.

5. Despite comparable fungal burden, Anxa2(-/-) mice died more rapidly than wild-type mice when infected with Cryptococcus neoformans, and Anxa2(-/-) mice exhibited enhanced inflammatory responses

6. annexin A2 contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa (zeige F10 Antikörper).

7. Our findings reveal a previously undemonstrated function for AnxA2 in inflammatory response in polymicrobial sepsis models

8. Podxl (zeige PODXL Antikörper)-overexpression in neural stem/progenitor cells leads to an up-regulation of Annexin A2.

9. The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4 (zeige NLRC4 Antikörper)-mediated inflammasome activation.

10. Data show that annexin A2 (AnxA2) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (zeige TLR4 Antikörper))-initiated TRAM protein (zeige TRAM2 Antikörper)-TRIF (zeige RNF138 Antikörper) protein pathway occurring on endosomes.