Angiotensin II Receptor-Associated Protein Proteine (AGTRAP)

AGTRAP encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. Zusätzlich bieten wir Ihnen Angiotensin II Receptor-Associated Protein Antikörper (61) und Angiotensin II Receptor-Associated Protein Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
AGTRAP 57085 Q6RW13
Ratte AGTRAP AGTRAP 298646 Q642A2
AGTRAP 11610 Q9WVK0
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,493.38
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,262.31
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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AGTRAP Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Angiotensin II Receptor-Associated Protein (AGTRAP) Interaktionspartnern

Human Angiotensin II Receptor-Associated Protein (AGTRAP) Interaktionspartner

  1. A role for AT1 receptor-associated proteins in blood pressure regulation

  2. ATRAP, a directly interacting and functionally inhibiting molecule of AT1R, plays a protective role against the development of systemic insulin resistance via regulatory effects on adipose tissue function.

  3. The phosphatidylinositol transfer protein RdgBbeta binds 14-3-3 via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).

  4. the GG genotype of the AGTRAP rs11121816 T/G single nucleotide polymorphism was associated with increased mortality in two cohorts of patients who had septic shock.

  5. CSF angiotensin II, ACE, and ACE2 levels are decreased in neuromyelitis optica/NMO spectrum disorder patients with anti-AQP4 antibody, reflecting severe destruction of perivascular astrocytes

  6. Endogenous increases in angiotensin II during dehydration contribute to dehydration-associated sympathoexcitation.

  7. Small interfering RNA significantly attenuates angiotensin II type 1 receptor-stimulated inositol phosphate formation.

  8. cloned a new human gene cDNA that codes for a homolog of the murine Agtrap protein

  9. isolation of a novel protein, ARAP1, which promotes recycling of angiotensin(1A) to the plasma membrane in HEK-293 cells

  10. mRNA is detected in all human tissues; cellular hypertrophy in cultured rat vascular smooth muscle and renal proximal tubular cells.

  11. CAML is an important signal transducer for the actions of Ang II in regulating the calcineurin-NFAT pathway and the interaction of CAML with ATRAP may mediate the Ang II actions in vascular physiology

Mouse (Murine) Angiotensin II Receptor-Associated Protein (AGTRAP) Interaktionspartner

  1. high glucose-induced podocytes damage by activating miR-370 signaling targeted to inhibit the expression of AGTRAP.

  2. verexpression of ATRAP induced adiponectin expression both in adipose tissue and primary adipocyte. Our data revealed that adipose ATRAP plays an important role in preventing metabolic disorders and adiponectin possibly mediates the effects of adipose ATRAP.

  3. ATRAP plays an important role in inhibiting kidney aging, possibly through sirtuin1-mediated mechanism independent of blocking AT1R signaling, and further protecting normal life span.

  4. Results presented in this study suggested that the enhancement in adipose ATRAP plays a protective role against the development of diet-induced visceral obesity and insulin resistance through improvement of adipose inflammation and function via the suppression of overactivation of adipose AT1R signaling.

  5. Renal ATRAP downregulation is involved in the onset and progression of blood pressure elevation caused by renal mass reduction, and implicates ATRAP as a therapeutic target for hypertension in chronic kidney disease.

  6. These results implied that AngII could effectively induce EpiCs to differentiate into vascular smooth muscle-like cells through the AT1 receptor.

  7. ATRAP expression in brown adipose tissue does not influence the pathogenesis of dietary obesity or metabolic disorders.

  8. Identify Atrap as a novel regulatory protein of the cardiac Ca(2+)-ATPase SERCA2a. Suggest that Atrap enhances the activity of SERCA2a and, consequently, facilitates ventricular relaxation.

  9. These results suggest that increased formation of AT1R-P2Y6R heterodimers with age may increase the likelihood of hypertension induced by Ang II.

  10. although erythropoiesis and blood pressure are negatively controlled through the AT1 receptor inhibition in vivo, the pathways involved are complex and distinct

  11. Distal tubule-dominant enhancement of ATRAP inhibits pathological renal sodium reabsorption and blood pressure elevation in response to high salt loading.

  12. AT1R knockout mice were less vulnerable to controlled cortical impact-induced injury.

  13. The inhibition of degradation of angiotensin II type 1 receptor-associated protein (ATRAP) and inactivation of AT1R-mediated p38 MAPK and STAT3 signaling pathways, are involved cardiac hypertrophy.

  14. Activation of aortic vascular ATRAP partially inhibits the Nox4/p22(phox)-ROS-p38MAPK/JNK pathway and pathological aortic hypertrophy provoked by Ang II-mediated hypertension.

  15. ATRAP, a directly interacting and functionally inhibiting molecule of AT1R, plays a protective role against the development of systemic insulin resistance via regulatory effects on adipose tissue function.

  16. AGTRAP expression is regulated by USF1 and USF2

  17. renal tubule-dominant ATRAP activation provokes no evident effects on blood pressure at baseline but exerts an inhibitory effect on the pathological elevation of blood pressure in response to angiotensin II stimulation

  18. These data imply an involvement of AT1R in fetal development and of AT2R in adult function.

  19. angiotensin-receptor-associated-protein and TRPV2 channel have roles in Angiotensin-2-mediated Ca2+ signaling in the retinal pigment epithelium

  20. These results suggest that the stimulation of mouse iPS cells with AT(1)R may enhance LIF-induced DNA synthesis, by augmenting the generation of superoxide and activating JAK/STAT3, and that AT(1)R stimulation may enhance Col IV-induced differentiation into mesodermal progenitor cells via p38 MAPK activation.

Angiotensin II Receptor-Associated Protein (AGTRAP) Protein Überblick

Protein Überblick

This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit AGTRAP

  • angiotensin II receptor associated protein (AGTRAP)
  • angiotensin II receptor-associated protein (Agtrap)
  • angiotensin II, type I receptor-associated protein (Agtrap)
  • 3300002E14Rik Protein
  • AGTRAP Protein
  • AT1R Protein
  • Atrap Protein
  • D4Wsu124e Protein
  • DKFZp469M235 Protein
  • LOC100223570 Protein

Bezeichner auf Proteinebene für AGTRAP

angiotensin II receptor-associated protein , type-1 angiotensin II receptor-associated protein , Type-1 angiotensin II receptor-associated protein , AT1 receptor-associated protein , ATI receptor-associated protein , angiotensin II, type I receptor-associated protein , AT1 receptor , angiotensin II receptor, type I

GENE ID SPEZIES
419491 Gallus gallus
457954 Pan troglodytes
508521 Bos taurus
608333 Canis lupus familiaris
100174244 Pongo abelii
100223570 Taeniopygia guttata
57085 Homo sapiens
298646 Rattus norvegicus
11610 Mus musculus
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