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APPBP2 encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family.
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It facilitates the regulator of calcineurin 1 (zeige RCAN1 Antikörper)-mediated apoptosis by downregulating proteasome subunits.
Association of the herpes simplex virus type 1 Us11 gene product with the cellular kinesin light-chain-related protein PAT1 results in the redistribution of both polypeptides.
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.
, amyloid beta precursor protein-binding protein 2
, amyloid protein-binding protein 2
, protein interacting with APP tail 1
, amyloid beta precursor protein (cytoplasmic tail) binding protein 2
, amyloid beta precursor protein-binding protein 2-like
, amyloid protein-binding protein 2-like