Alkaline Ceramidase 1 Proteine (ACER1)

Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Zusätzlich bieten wir Ihnen ACER1 Antikörper (43) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ACER1 125981 Q8TDN7
ACER1 171168 Q8R4X1
Ratte ACER1 ACER1 301118  
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Showing 3 out of 3 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
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Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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ACER1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Alkaline Ceramidase 1 (ACER1) Interaktionspartnern

Human Alkaline Ceramidase 1 (ACER1) Interaktionspartner

  1. upregulation of haCER1 and AC mediates the Ca2 (zeige CA2 Proteine)+(o)-induced growth arrest and differentiation of keratinocytes by generating sphingosine and its phosphate

Mouse (Murine) Alkaline Ceramidase 1 (ACER1) Interaktionspartner

  1. Loss of Acer1 elevated the levels of various ceramides and sphingoid bases in the skin and caused progressive hair loss in mice.

  2. In conclusion, the present study unraveled ceramidase as a crucial player in sphingosine-induced platelet activation following GPVI (zeige GP6 Proteine)-dependent signaling.

ACER1 Protein Überblick

Protein Überblick

Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006

Genbezeichner und Symbole assoziert mit Alkaline Ceramidase 1 Proteine (ACER1)

  • alkaline ceramidase 1 (ACER1)
  • alkaline ceramidase 1 (acer1)
  • alkaline ceramidase 1 (Acer1)
  • 2310024P18Rik Protein
  • AI662009 Protein
  • Alkcdase1 Protein
  • Asah3 Protein
  • Cer1 Protein
  • zgc:110285 Protein

Bezeichner auf Proteinebene für Alkaline Ceramidase 1 Proteine (ACER1)

N-acylsphingosine amidohydrolase (alkaline ceramidase) 3 , alkaline ceramidase 1 , N-acylsphingosine amidohydrolase 3 , acylsphingosine deacylase 3 , alkCDase 1 , alkaline CDase 1 , alkaline cdase 1 , maCER1

GENE ID SPEZIES
518021 Bos taurus
611739 Canis lupus familiaris
699093 Macaca mulatta
100127603 Xenopus (Silurana) tropicalis
100357548 Oryctolagus cuniculus
468681 Pan troglodytes
550266 Danio rerio
125981 Homo sapiens
171168 Mus musculus
301118 Rattus norvegicus
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