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The protein encoded by AP3M1 is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. Zusätzlich bieten wir Ihnen AP3M1 Antikörper (43) und und viele weitere Produktgruppen zu diesem Protein an.
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Structural basis for the recognition of tyrosine-based sorting signals by the mu3A subunit of the AP-3 adaptor complex
Data indicate that AP-3 facilitates PAR1 (zeige MARK2 Proteine) interaction with ALIX (zeige PDCD6IP Proteine).
results demonstrate that the intact and stable AP-3 complex is required for HIV-1 assembly and release, and the involvement of the AP-3 complex in late stages of the HIV-1 replication cycle is independent of clathrin-mediated endocytosis
The present results suggest that AP3 complex genes might not play a major role in the pathogenesis of schizophrenia.
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.
AP-3 adapter complex mu3A subunit
, AP-3 complex subunit mu-1
, adapter-related protein complex 3 mu-1 subunit
, clathrin adaptor complex AP3, mu-3A subunit
, mu-adaptin 3A
, adaptor-related protein complex AP-3, mu 1 subunit
, clathrin adaptor protein mu3A
, HA1 47 kDa subunit homolog 1
, Mu-adaptin 3A
, adaptor-related protein complex AP-3 mu 1 subunit
, clathrin assembly protein assembly protein complex 1 medium chain homolog 1
, clathrin coat assembly protein AP47 homolog 1
, clathrin coat-associated protein AP47 homolog 1
, clathrin-associated adaptor protein homolog (p47A)
, golgi adaptor AP-1 47 kDa protein homolog 1