Activated Leukocyte Cell Adhesion Molecule Proteine (ALCAM)

ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. Zusätzlich bieten wir Ihnen CD166 Antikörper (247) und CD166 Kits (75) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ALCAM 214 Q13740
ALCAM 11658 Q61490
ALCAM 79559 O35112
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Top CD166 Proteine auf antikoerper-online.de

Showing 10 out of 42 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Maus Fc Tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$272.80
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,626.01
Details
HEK-293 Cells Human His tag 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$590.00
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Human Cells Ratte Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Human Cells Cynomolgus His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$272.80
Details
Human Cells Cynomolgus Fc Tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Escherichia coli (E. coli) Human His tag Activated Leukocyte Cell Adhesion Molecule (ALCAM) (AA 28-516), (partial) protein (His tag) 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$242.00
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$640.00
Details

ALCAM Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , ,
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Mouse (Murine) , ,
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Rat (Rattus) , ,
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Am meisten referenzierte CD166 Proteine

  1. Mouse (Murine) CD166 Protein expressed in Human Cells - ABIN2007131 : Bowen, Patel, Li, Modrell, Malacko, Wang, Marquardt, Neubauer, Pesando, Francke: Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. in The Journal of experimental medicine 1995 (PubMed)
    Show all 5 Pubmed References

  2. Human CD166 Protein expressed in Wheat germ - ABIN1344804 : Delgado, Nugnes, Colombo, Troncoso, Fernández, Malchiodi, Frahm, Croci, Compagno, Rabinovich, Wolfenstein-Todel, Elola: Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011 (PubMed)

Weitere Proteine zu Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartnern

Zebrafish Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. Alcama mediates Edn1 (zeige EDN1 Proteine) signaling during zebrafish cartilage morphogenesis.

Xenopus laevis Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. The cell-adhesion molecule (zeige MCAM Proteine) Alcam is required for proper nephrogenesis and functions downstream of Fzd3 (zeige FZD3 Proteine) during embryonic kidney development.

Atlantic Salmon (Salmo salar) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. No significant association between ALCAM expression and survival data was observed for all tumors

Human Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. Activated leukocyte cell adhesion molecule (ALCAM) has been implicated in tumorigenesis.

  2. this study establishes for the first time that CD166 is the ligand of ILT3. Blockade of CD166 by ILT3.Fc inhibited progression of human tumor cell lines in NOD.Cg-Prkdc (zeige PRKDC Proteine) Il-2rg (zeige IL2RG Proteine)/SzJ mice, suggesting its potential immunotherapeutic value.

  3. These data indicate that cardiac surgery influences the expression of CD162 (zeige SELPLG Proteine), CD166 and CD195 and that the intensity of the immune system response, displayed as the change in the CD162 (zeige SELPLG Proteine), CD166, CD195 expression, varies, depending on the surgical technique used.

  4. These findings indicate that high ALCAM expression is associated with poor prognosis and advanced clinicopathological characteristics in CRC (zeige CALR Proteine) patients.

  5. ALCAM is a potential mediator in the late complications of diabetes in the kidney.

  6. we show that although the histological detection of ALCAM within the tumor tissue correlates strongly with tumor stage in BCa (zeige BLNK Proteine) (Figure (Figure2),2), it does not appear to be prognostic of overall survival. In contrast, urine ALCAM correlates with tumor stage and is a significant independent predictor of 3-year overall survival for patients after cystectomy.

  7. Our data indicate that Gal-8 interacts with ALCAM at the surface of breast cancer cells through glycosylation-dependent mechanisms. A novel heterophilic interaction between ALCAM and Gal-8 is demonstrated here, suggesting its physiologic relevance in the biology of breast cancer cells

  8. CD166 functions as a risk factor for cancers, and the alterations of its different functional isoforms were observed to correlate with specific or interplayed clinical outcomes.

  9. The results highlight the potential of ALCAM as a recurrent biomarker in early-stage endometrioid endometrial cancer and point to ALCAM as an important molecule in endometrial cancer dissemination by regulating cell migration, invasion, and metastasis.

  10. MiR (zeige MLXIP Proteine)-148a and miR (zeige MLXIP Proteine)-152 can sensitize tamoxifen-resistant MCF-7 breast cancer cells to tamoxifen via downregulating ALCAM.

Mouse (Murine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. Our data demonstrate that ALCAM KO mice develop a more severe active experimental autoimmune encephalomyelitis, which can be explained by an increased permeability of their BBB. This loss in BBB integrity is due to a dysregulation of junctional molecules caused by the lack of ALCAM at the level of the TJ molecules.

  2. demonstrates for the first time the in vivo contribution of ALCAM to angiogenesis and reveals a novel role of stromally expressed ALCAM in supporting tumor growth and metastatic spread

  3. Our results indicate that the loss of CD166 impacts hematopoietic stem cell numbers

  4. Data indicate that the CD166/AKT (zeige AKT1 Proteine) axis modulates tumorigenesis via promotion of phosphorylation and facilitation of degradation, ubiquitination and cytosolic accumulation of FOXO (zeige FOXO3 Proteine) proteins in liver cancer cells.

  5. ALCAM stably interacts with actin by binding to syntenin-1 (zeige SDCBP Proteine) and ezrin (zeige EZR Proteine).

  6. CD166/ALCAM (ALCAM) is a close structural and functional homolog of RAGE (zeige AGER Proteine); it shows that binding of S100B (zeige S100B Proteine) to CD166/ALCAM induces dose- and time-dependent expression of NF-kappaB (zeige NFKB1 Proteine) family members in wild type and RAGE (zeige AGER Proteine)-deficient mouse endothelial cells.

  7. Activated Leukocyte Cell Adhesion Molecule (ALCAM) or CD166 expression on osteoblasts is directly correlated with Runx2 (zeige RUNX2 Proteine) expression and high hematopoiesis enhancing activity.

  8. Behavioral deficits caused by prolonged IFN alpha (zeige IFNA Proteine) treatment were not prevented by blocking ALCAM, which is involved in immune cell entry to the brain.

  9. novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network.

  10. The presence of CD166 on prostate stem/progenitors and castration resistant sub-populations suggest that it is a cell surface molecule with the potential for targeted delivery of human prostate cancer therapeutics.

Pig (Porcine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.

CD166 (ALCAM) Protein Überblick

Protein Überblick

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Genbezeichner und Symbole assoziert mit ALCAM

  • activated leukocyte cell adhesion molecule a (alcama)
  • activated leukocyte cell adhesion molecule L homeolog (alcam.L)
  • activated leukocyte cell adhesion molecule (ALCAM)
  • activated leukocyte cell adhesion molecule (alcam)
  • CD166 antigen homolog (cd166)
  • activated leukocyte cell adhesion molecule (Alcam)
  • AI853494 Protein
  • ALCAM Protein
  • BEN Protein
  • CD166 Protein
  • DM-GRASP Protein
  • JC7 Protein
  • MEMD Protein
  • MuSC Protein
  • SC1 Protein

Bezeichner auf Proteinebene für ALCAM

CD166 antigen homolog A , DM-GRASP homolog , neurolin , neurolin-a , zn5 / zn-5 antigen , zn8 / zn-8 antigen , activated leukocyte cell adhesion molecule , CD166 antigen , DM-GRASP II , CD166 antigen-like , CD166 antigen homolog , HB2 , KG-CAM , SB-10 antigen , activated leucocyte cell adhesion molecule , BEN glycoprotein , SC1 glycoprotein

GENE ID SPEZIES
30194 Danio rerio
444425 Xenopus laevis
460565 Pan troglodytes
703777 Macaca mulatta
780210 Xenopus (Silurana) tropicalis
100061848 Equus caballus
100173616 Pongo abelii
100473255 Ailuropoda melanoleuca
100286453 Salmo salar
100015168 Monodelphis domestica
100598547 Nomascus leucogenys
214 Homo sapiens
11658 Mus musculus
79559 Rattus norvegicus
281614 Bos taurus
396092 Gallus gallus
100009305 Oryctolagus cuniculus
478550 Canis lupus familiaris
397269 Sus scrofa
100726386 Cavia porcellus
101114151 Ovis aries
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