anti-Activated Leukocyte Cell Adhesion Molecule (ALCAM) Antikörper

ALCAM encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. Zusätzlich bieten wir Ihnen CD166 Kits (74) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ALCAM 214 Q13740
ALCAM 11658 Q61490
ALCAM 79559 O35112
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Top anti-CD166 Antikörper auf antikoerper-online.de

Showing 10 out of 247 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Biotin Func, FACS   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$522.50
Details
Human Maus Unkonjugiert Func, FACS   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$478.50
Details
Human Maus Unkonjugiert ELISA, IHC Figure 1: Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (A), kidney carcinoma (B), lung carcinoma (C) and breast carcinoma (D), showing cytoplasmic and membrane localization with DAB staining using ALCAM mouse mAb. Dilution: 1/200 - 1/1000 Figure 1: Western blot analysis using FRK mouse mAb against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY FRK cDNA (2). Dilution: 1:500~~2000 100 μL Anmelden zum Anzeigen 10 bis 11 Tage
$439.57
Details
Hund Ziege Unkonjugiert CyTOF, FACS, ICC, IHC, SimWes, WB Detection of ALCAM/CD166 in Canine PBMCs by Flow Cytometry. Canine peripheral blood mononuclear cells (PBMCs) treated with PMA and Calcium Ionomycin for 24 hours were stained with Goat Anti-Mouse/Rat/Canine ALCAM/CD166 Antigen Affinity-purified Polyclonal Antibody. Detection of ALCAM/CD166 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes either (A) activated or (B) resting were stained with Goat Anti-Mouse/Rat/Canine ALCAM/CD166 Antigen Affinity-purified Polyclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Maus Unkonjugiert ICC, FACS, IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus Unkonjugiert FACS, IHC, ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus PE FACS Detection of ALCAM/CD166 in Human Whole Blood Lymphocytes by Flow Cytometry. Human whole blood lymphocytes were stained with Mouse Anti-Human ALCAM/CD166 PE-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$328.90
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of CD166/ALCAM using anti- CD166/ALCAM antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat brain tissue lysates,   Lane 2: mouse brain tissue lysates,   Lane 3: A549 whole Cell lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- CD166/ALCAM antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CD166/ALCAM at approximately 100KD. The expected band size for CD166/ALCAM is at 65KD. IHC analysis of CD166/ALCAM using anti- CD166/ALCAM antibody . CD166/ALCAM was detected in paraffin-embedded section of mouse gaster tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti- CD166/ALCAM Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Maus Unkonjugiert ELISA, FACS, IF/ICC, IHC, WB 100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Western blot analysis using ALCAM mouse mAb against truncated Trx-ALCAM recombinant protein (1). Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 10 bis 11 Tage
$439.57
Details

Am meisten referenzierte anti-CD166 Antikörper

  1. Human Monoclonal CD166 Primary Antibody für FACS - ABIN4897157 : Soh, Zheng, Li Yeo, Yang, Ng, Wong, Zhang, Li, Nichane, Asmat, Wong, Wong, Su, Mantalaris, Lu, Xian, McKeon, Chen, Lim, Lim: CD166(pos) subpopulation from differentiated human ES and iPS cells support repair of acute lung injury. in Molecular therapy : the journal of the American Society of Gene Therapy 2012 (PubMed)
    Show all 10 Pubmed References

  2. Dog (Canine) Polyclonal CD166 Primary Antibody für CyTOF, FACS - ABIN4900087 : Stanton, Beier: Inhibition of p38 MAPK signaling in chondrocyte cultures results in enhanced osteogenic differentiation of perichondral cells. in Experimental cell research 2006 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal CD166 Primary Antibody für Func, IHC (fro) - ABIN2191863 : Zimmerman, Joosten, Torensma, Parnes, van Leeuwen, Figdor: Long-term engagement of CD6 and ALCAM is essential for T-cell proliferation induced by dendritic cells. in Blood 2006 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal CD166 Primary Antibody für Func, FACS - ABIN610439 : Bennett, Calakos, Scheller: Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. in Science (New York, N.Y.) 1992 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal CD166 Primary Antibody für Func, FACS - ABIN610440 : Faigle, Colucci-Guyon, Louvard, Amigorena, Galli: Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery. in Molecular biology of the cell 2000 (PubMed)
    Show all 5 Pubmed References

  6. Human Monoclonal CD166 Primary Antibody für IHC, ELISA - ABIN968954 : Fujiwara, Tatsumi, Kosaka, Sato, Higuchi, Yoshioka, Maeda, Ueda, Fujii: Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166). in The Journal of clinical endocrinology and metabolism 2003 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal CD166 Primary Antibody für CyTOF, ELISA (Capture) - ABIN4900083 : Ihnen, Kress, Kersten, Kilic, Choschzick, Zander, Müller, Mahner, Jänicke, Woelber, Milde-Langosch: Relevance of activated leukocyte cell adhesion molecule (ALCAM) in tumor tissue and sera of cervical cancer patients. in BMC cancer 2012 (PubMed)
    Show all 4 Pubmed References

  8. Human Polyclonal CD166 Primary Antibody für IHC, IHC (p) - ABIN4279141 : Ishiguro, Murakami, Mizuno, Fujii, Kondo, Usami, Taniguchi, Yokoi, Osada, Sekido: Membranous expression of activated leukocyte cell adhesion molecule contributes to poor prognosis and malignant phenotypes of non-small-cell lung cancer. in The Journal of surgical research 2012 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal CD166 Primary Antibody für IHC, ELISA - ABIN1098107 : Rauch, Rosenkranz, Böhm, Meyer-Kirchrath, Hohlfeld, Schrör, Rauch: Cholesterol induces apoptosis-associated loss of the activated leukocyte cell adhesion molecule (ALCAM) in human monocytes. in Vascular pharmacology 2011 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal CD166 Primary Antibody für FACS, IF (p) - ABIN673944 : Lee, Lee, Huang, Chang, Lin, Chien, Yang, Lin: Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells. in PLoS ONE 2014 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen CD166 Interaktionspartner

Zebrafish Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. Alcama mediates Edn1 (zeige EDN1 Antikörper) signaling during zebrafish cartilage morphogenesis.

Xenopus laevis Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. The cell-adhesion molecule (zeige MCAM Antikörper) Alcam is required for proper nephrogenesis and functions downstream of Fzd3 (zeige FZD3 Antikörper) during embryonic kidney development.

Atlantic Salmon (Salmo salar) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. No significant association between ALCAM expression and survival data was observed for all tumors

Human Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. These data indicate that cardiac surgery influences the expression of CD162 (zeige SELPLG Antikörper), CD166 and CD195 and that the intensity of the immune system response, displayed as the change in the CD162 (zeige SELPLG Antikörper), CD166, CD195 expression, varies, depending on the surgical technique used.

  2. These findings indicate that high ALCAM expression is associated with poor prognosis and advanced clinicopathological characteristics in CRC (zeige CALR Antikörper) patients.

  3. ALCAM is a potential mediator in the late complications of diabetes in the kidney.

  4. we show that although the histological detection of ALCAM within the tumor tissue correlates strongly with tumor stage in BCa (zeige BLNK Antikörper) (Figure (Figure2),2), it does not appear to be prognostic of overall survival. In contrast, urine ALCAM correlates with tumor stage and is a significant independent predictor of 3-year overall survival for patients after cystectomy.

  5. Our data indicate that Gal-8 interacts with ALCAM at the surface of breast cancer cells through glycosylation-dependent mechanisms. A novel heterophilic interaction between ALCAM and Gal-8 is demonstrated here, suggesting its physiologic relevance in the biology of breast cancer cells

  6. CD166 functions as a risk factor for cancers, and the alterations of its different functional isoforms were observed to correlate with specific or interplayed clinical outcomes.

  7. The results highlight the potential of ALCAM as a recurrent biomarker in early-stage endometrioid endometrial cancer and point to ALCAM as an important molecule in endometrial cancer dissemination by regulating cell migration, invasion, and metastasis.

  8. MiR (zeige MLXIP Antikörper)-148a and miR (zeige MLXIP Antikörper)-152 can sensitize tamoxifen-resistant MCF-7 breast cancer cells to tamoxifen via downregulating ALCAM.

  9. CHIP directly regulates the stability of CD166 protein through the ubiquitin proteasome system.

  10. ALCAM is overexpressed on the surface of Human T-lymphotropic virus type 1-infected lymphocytes, both in chronically infected cell lines and in primary infected CD4 (zeige CD4 Antikörper)(+) T lymphocytes.

Mouse (Murine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. Our data demonstrate that ALCAM KO mice develop a more severe active experimental autoimmune encephalomyelitis, which can be explained by an increased permeability of their BBB (zeige ALMS1 Antikörper). This loss in BBB (zeige ALMS1 Antikörper) integrity is due to a dysregulation of junctional molecules caused by the lack of ALCAM at the level of the TJ molecules.

  2. demonstrates for the first time the in vivo contribution of ALCAM to angiogenesis and reveals a novel role of stromally expressed ALCAM in supporting tumor growth and metastatic spread

  3. Our results indicate that the loss of CD166 impacts hematopoietic stem cell numbers

  4. Data indicate that the CD166/AKT (zeige AKT1 Antikörper) axis modulates tumorigenesis via promotion of phosphorylation and facilitation of degradation, ubiquitination and cytosolic accumulation of FOXO (zeige FOXO3 Antikörper) proteins in liver cancer cells.

  5. ALCAM stably interacts with actin by binding to syntenin-1 (zeige SDCBP Antikörper) and ezrin (zeige EZR Antikörper).

  6. CD166/ALCAM (ALCAM) is a close structural and functional homolog of RAGE (zeige AGER Antikörper); it shows that binding of S100B (zeige S100B Antikörper) to CD166/ALCAM induces dose- and time-dependent expression of NF-kappaB (zeige NFKB1 Antikörper) family members in wild type and RAGE (zeige AGER Antikörper)-deficient mouse endothelial cells.

  7. Activated Leukocyte Cell Adhesion Molecule (ALCAM) or CD166 expression on osteoblasts is directly correlated with Runx2 (zeige RUNX2 Antikörper) expression and high hematopoiesis enhancing activity.

  8. Behavioral deficits caused by prolonged IFN alpha (zeige IFNA Antikörper) treatment were not prevented by blocking ALCAM, which is involved in immune cell entry to the brain.

  9. novel role for ALCAM in stabilizing LEC-LEC interactions and in the organization and function of the LV network.

  10. The presence of CD166 on prostate stem/progenitors and castration resistant sub-populations suggest that it is a cell surface molecule with the potential for targeted delivery of human prostate cancer therapeutics.

Pig (Porcine) Activated Leukocyte Cell Adhesion Molecule (ALCAM) Interaktionspartner

  1. ALCAM up-regulation by hypercholesterolemia suggests a side-specific spatial role in the recruitment of leukocytes to aortic valve sclerosis sites.

CD166 (ALCAM) Antigen-Profil

Protein Überblick

This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Genbezeichner und Symbole assoziert mit ALCAM

  • activated leukocyte cell adhesion molecule a (alcama) Antikörper
  • activated leukocyte cell adhesion molecule L homeolog (alcam.L) Antikörper
  • activated leukocyte cell adhesion molecule (ALCAM) Antikörper
  • activated leukocyte cell adhesion molecule (alcam) Antikörper
  • CD166 antigen homolog (cd166) Antikörper
  • activated leukocyte cell adhesion molecule (Alcam) Antikörper
  • AI853494 Antikörper
  • ALCAM Antikörper
  • BEN Antikörper
  • CD166 Antikörper
  • DM-GRASP Antikörper
  • JC7 Antikörper
  • MEMD Antikörper
  • MuSC Antikörper
  • SC1 Antikörper

Bezeichner auf Proteinebene für ALCAM

CD166 antigen homolog A , DM-GRASP homolog , neurolin , neurolin-a , zn5 / zn-5 antigen , zn8 / zn-8 antigen , activated leukocyte cell adhesion molecule , CD166 antigen , DM-GRASP II , CD166 antigen-like , CD166 antigen homolog , HB2 , KG-CAM , SB-10 antigen , activated leucocyte cell adhesion molecule , BEN glycoprotein , SC1 glycoprotein

GENE ID SPEZIES
30194 Danio rerio
444425 Xenopus laevis
460565 Pan troglodytes
703777 Macaca mulatta
780210 Xenopus (Silurana) tropicalis
100061848 Equus caballus
100173616 Pongo abelii
100473255 Ailuropoda melanoleuca
100286453 Salmo salar
100015168 Monodelphis domestica
100598547 Nomascus leucogenys
214 Homo sapiens
11658 Mus musculus
79559 Rattus norvegicus
281614 Bos taurus
396092 Gallus gallus
100009305 Oryctolagus cuniculus
478550 Canis lupus familiaris
397269 Sus scrofa
100726386 Cavia porcellus
101114151 Ovis aries
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