anti-ATPase Family, AAA Domain Containing 5 (ATAD5) Antikörper

Involved in DNA damage response. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ATAD5 79915 Q96QE3
ATAD5 237877 Q4QY64
ATAD5 303348  
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Top anti-ATPase Family, AAA Domain Containing 5 Antikörper auf antikoerper-online.de

Showing 10 out of 43 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IP, PLA, WB Western Blot and Immunoprecipitation: ATAD5/FRAG1 Antibody [ABIN252833] Detection of Human ATAD5/FRAG1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibody: Affinity purified rabbit anti-ATAD5/FRAG1 antibody ABIN252833 used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate.  Detection: Chemiluminescence with exposure times of 30 seconds (A and B). Proximity Ligation Assay: Atad5 Antibody [ABIN2528335] - The image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red) 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$619.30
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$639.83
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti ATAD5 Polyclonal Antibody,Unconjugated (ABIN872440) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Maus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using ATAD5 polyclonal antibody  shows detection of a band ~120 KDa corresponding to human ATAD5 (arrowhead) in various cell lysates. Lanes contain ~ 5 ug of HeLa nuclear extract (1), HeLa (2), A-431 (3), Jurkat (4) and HEK293 (5) whole cell lysates. After SDS-PAGE, transfer and blocking, the membrane was probed with the primary antibody diluted to 1:500. The membrane was then washed and reacted with a HRP conjugated Gt-a-Rabbit IgG [H&L] MX followed by ECL detection using a 2m exposure time. The expected molecular weight of ATAD5 is 120 KDa according to Kanellis P et al. 2003, although the predicted molecular weight is 207 KDa. The 50 KDa bands in Jurkat and 293 cell lysates are probably cross-reaction with other proteins. Both the 120 KDa and 50 KDa bands are not observed when antibody is pre-incubated with peptide (datanot shown). 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$576.53
Details
Maus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Ratte Ziege FITC ELISA   100 μL Anmelden zum Anzeigen 16 Days
$653.71
Details

Weitere Antikörper gegen ATPase Family, AAA Domain Containing 5 Interaktionspartner

Human ATPase Family, AAA Domain Containing 5 (ATAD5) Interaktionspartner

  1. Report rare ATAD5 missense mutations may contribute to genetic susceptibility breast cancer and epithelial ovarian carcinoma.

  2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia (zeige PALB2 Antikörper) pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review]

  3. Elg1 has an important role in maintaining chromosome integrity by regulating PCNA (zeige PCNA Antikörper) levels on chromatin, thereby acting as a PCNA (zeige PCNA Antikörper) unloading factor.

  4. ATAD5 regulates the cycle of DNA replication factories, probably through its PCNA (zeige PCNA Antikörper)-unloading activity.

  5. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis.

  6. Studies indicate that USP1 (zeige USP1 Antikörper) and ELG1 as regulators of PCNA (zeige PCNA Antikörper) ubiquitylation.

  7. Human ELG1 protein is stabilized and localized to form foci at sites of stalled DNA replications that are different from DNA double strand breaks foci.

  8. The Frag1 signal pathway, by linking replication stress surveillance with apoptosis induction, plays a central role in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis.

Mouse (Murine) ATPase Family, AAA Domain Containing 5 (ATAD5) Interaktionspartner

  1. Atad5+/m cells accumulate in the S phase, have decreased proliferation, and have reduced double-strand breaks, class switch recombination, and translocations

  2. Authors discuss many functions of Elg1 protein as embryonic lethal when lost in mice, as a tumor suppressor in mice and humans, interacts with human Fanconi Anemia (zeige PALB2 Antikörper) pathway and may contribute to some of the phenotypes associated with neurofibromatosis. [Review]

  3. loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis.

ATPase Family, AAA Domain Containing 5 (ATAD5) Antigen-Profil

Protein Überblick

Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis.

Genbezeichner und Symbole assoziert mit ATAD5

  • ATPase family, AAA domain containing 5 (ATAD5) Antikörper
  • ATPase family, AAA domain containing 5a (atad5a) Antikörper
  • ATPase family, AAA domain containing 5 (Atad5) Antikörper
  • atad5 Antikörper
  • C17orf41 Antikörper
  • C130052G03Rik Antikörper
  • cb14 Antikörper
  • ELG1 Antikörper
  • FRAG1 Antikörper
  • Gm17 Antikörper
  • im:7138471 Antikörper
  • RGD1561464 Antikörper
  • sb:cb14 Antikörper
  • si:ch211-11k18.10 Antikörper
  • Si:ch211-11k18.10 protein-like Antikörper
  • wu:fi03a11 Antikörper

Bezeichner auf Proteinebene für ATAD5

ATPase family, AAA domain containing 5 , chromosome fragility associated gene 1 , ATPase family AAA domain-containing protein 5-like , ATPase family AAA domain-containing protein 5 , chromosome fragility-associated gene 1 protein , enhanced level of genomic instability 1 homolog , enhanced level of genomic instability gene 1

GENE ID SPEZIES
454559 Pan troglodytes
560591 Danio rerio
100018805 Monodelphis domestica
100058527 Equus caballus
100350844 Oryctolagus cuniculus
100391218 Callithrix jacchus
100471983 Ailuropoda melanoleuca
100219192 Taeniopygia guttata
79915 Homo sapiens
237877 Mus musculus
417408 Gallus gallus
491156 Canis lupus familiaris
100522895 Sus scrofa
513059 Bos taurus
303348 Rattus norvegicus
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