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The protein encoded by ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCE1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal ABCE1 Primary Antibody für ICC, IF - ABIN152893
Chen, Dong, Ishimura, Daar, Hinnebusch, Dean: The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors. in The Journal of biological chemistry 2006
Show all 2 Pubmed References
Human Polyclonal ABCE1 Primary Antibody für ELISA, WB - ABIN409078
Shichijo, Ishihara, Azuma, Komatsu, Higashimoto, Ito, Nakamura, Ueno, Harada, Itoh: ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients. in Oncology reports 2005
Induction of ribosome rescue factors PELO and HBS1L is required to support protein synthesis when ABCE1 levels fall in platelets, including for hemoglobin production during blood cell development.
ABCE1 is involved in histone biosynthesis and DNA replication and therefore is essential for normal S phase progression.
The present study reported on the effects of ABCE1 overexpression on lung adenocarcinoma cells in vitro, demonstrating its enhancing effect on cell proliferation and invasiveness with simultaneous downregulation of p27 (zeige PAK2 Antikörper) protein expression.
ABCE1 plays an essential role in the progression and metastasis of lung cancers and may represent a valuable therapeutic target for the management of lung tumor
miR (zeige MLXIP Antikörper)-299-3p promotes the sensibility of lung cancer to doxorubicin through suppression of ABCE1, at least partly. Therefore, the disordered decreased of miR (zeige MLXIP Antikörper)-299-3p and resulting ABCE1 up-expression may contribute to chemoresistance of lung cancer
Expression of the ABCE1-silencing gene, transfected by electrotransfer, could inhibit the proliferation, invasion, and migration of thyroid cancer cells.
Downregulation of ABCE1 via siRNA affects the sensitivity of lung cancer cells against chemotherapeutic agents.
ABCE1 is closely associated with cell proliferation, invasion and migration in esophageal cancer and silencing the ABCE1 gene by electroporation can significantly reduce the proliferation, invasion and migration capacity
ABCE1 is able to suppress RNA silencing in Nicotiana benthamiana plants, in mammalian HEK293 cells and in the worm Caenorhabditis elegans.
ABCE1 is closely connected with the pathogenesis and development of oral cancer, which acts through the cellular pathways of 2-5A/RNase L (zeige RNASEL Antikörper).
Expression of RNase L (zeige RNASEL Antikörper) is a signal generated by NMDA receptor in cortical neurons. RNase L (zeige RNASEL Antikörper) expression and RNA degradation may be events that cause neuronal damage induced by NMDA receptor activation.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
ATP-binding cassette, sub-family E (OABP), member 1
, ABC transporter-related protein
, RNaseL inhibitor-like protein
, ATP-binding cassette, sub-family E, member 1
, ATP-binding cassette sub-family E member 1-like
, RNAse L inhibitor
, RNase L inhibitor
, 2'-5'-oligoadenylate-binding protein
, ATP-binding cassette sub-family E member 1
, ribonuclease 4 inhibitor
, ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
, ATP-binding cassette, subfamily E, member 1
, RNS4l (Eye)
, ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor